Title: COPD (Chronic Obstructive Pulmonary Disease)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 5/6/2022 12:00:00 AM

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In what has been a long period of relative low activity, FDA’s OPDP has taken the opportunity to remind us that low enforcement does not mean no enforcement when it comes to promotional speech by pharmaceutical companies. This past June … Continue reading →

For the second time this month and the third time this year, FDA’s OPDP has posted notice that it has taken an enforcement action. Last week, a Warning Letter was posted regarding a sales aid. This week it action came … Continue reading →

While enforcement has been at a low ebb for quite some time with FDA’s Office of Prescription Drug Promotion (OPDP), this week took a different turn with the posting of two new untitled letters sent October 31. That brings the … Continue reading →

Last week FDA’s Office of Prescription Drug Promotion issued its first regulatory action letter of the year. This was an Untitled Letter – a/k/a Notice of Violation Letter (NOV) – sent by the agency to Novartis in relation to promotional … Continue reading →

Villejuif, France – Frequent use of workplace disinfectants may increase health care workers’ risk of developing chronic obstructive pulmonary disease, suggest researchers from France’s National Institute of Health and Medical Research.

Villejuif, France — Frequent use of common cleaning products and disinfectants at work may increase female nurses’ risk of developing chronic obstructive pulmonary disease by up to 38%, results of a recent study led by researchers from France’s National Institute of Health and Medical Research suggest.

London — Workers who use cleaning and disinfecting products may be more likely to develop asthma and chronic obstructive pulmonary disease – 50% and 43%, respectively – than those who don’t, results of a recent study led by British and Italian researchers show.

Silver Spring, MD — Workers in construction trades are at “significantly” higher risk for chronic obstructive pulmonary disease than non-construction workers, according to the results of a recent study.

London — Workers exposed to pesticides may face a higher risk of developing chronic obstructive pulmonary disease, results of a recent study led by British researchers suggest.

Atlanta — An elevated risk of death linked to chronic obstructive pulmonary disease among workers in certain industries and occupations highlights the need for better employee health policies and targeted interventions, according to a new report from the Centers for Disease Control and Prevention.

This Partnership is a significant milestone in 1st Class Medical's commitment to advancing respiratory health awareness, education, and support for individuals affected by chronic obstructive pulmonary disease (COPD) and other lung conditions.

Title: Early COPD Treatment Slows Disease
Category: Health News
Created: 8/28/2009 12:00:00 AM
Last Editorial Review: 8/28/2009 12:00:00 AM

Title: Health Tip: Recognizing COPD
Category: Health News
Created: 8/25/2010 10:10:00 AM
Last Editorial Review: 8/25/2010 12:00:00 AM

Title: Health Tip: Help Keep COPD in Check
Category: Health News
Created: 8/31/2012 8:05:00 AM
Last Editorial Review: 8/31/2012 12:00:00 AM

BACKGROUND:Home noninvasive ventilation (NIV) may improve chronic hypercarbia in COPD and patient-important outcomes. The efficacy of home high-flow nasal cannula (HFNC) as an alternative is unclear.METHODS:We searched MEDLINE, Embase, Cochrane CENTRAL, Scopus, and ClinicalTrials.gov for randomized trials of subjects from inception to March 31, 2023, and updated the search on July 14, 2023. We performed a frequentist network meta-analysis and assessed the certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation approach. We analyzed randomized controlled trials (RCTs) comparing NIV, HFNC, or standard care in adult subjects with COPD with chronic hypercapnic respiratory failure. Outcomes included mortality, COPD exacerbations, hospitalizations, and quality of life (St George Respiratory Questionnaire [SGRQ]).RESULTS:We analyzed 24 RCTs (1,850 subjects). We found that NIV may reduce the risk of death compared to standard care (relative risk 0.82 [95% CI 0.66–1.00]) and probably reduces exacerbations (relative risk 0.71 [95% CI 0.58–0.87]). HFNC probably reduces exacerbations compared to standard care (relative risk 0.77 [0.68–0.88]), but its effect on mortality is uncertain (relative risk 1.20 [95% CI 0.63–2.28]). HFNC probably improves SGRQ scores (mean difference −7.01 [95% CI −12.27 to −1.77]) and may reduce hospitalizations (relative risk 0.87 [0.69–1.09]) compared to standard care. No significant difference was observed between HFNC and NIV in reducing exacerbations.CONCLUSIONS:Both NIV and HFNC reduce exacerbation risks in subjects with COPD compared to standard care. HFNC may offer advantages in improving quality of life.

Introduction

Exacerbation of COPD complicated by respiratory acidaemia is the commonest indication for noninvasive ventilation (NIV). The NIV outcomes (NIVO) score offers the best estimate of survival for those ventilated. Unfortunately, two-thirds of cases of COPD are unrecognised, and patients may present without COPD having been confirmed by spirometry.

COPD is a heterogeneous condition, with tobacco smoking being the main environmental risk factor. The presence of type 2 (T2) inflammation is a well-recognised feature of asthma; however, it is now apparent that a subset of COPD patients also displays evidence of T2 inflammation with respect to elevated eosinophil counts and altered gene and protein expression of several T2 inflammatory mediators. T2 inflammatory mediators represent an attractive therapeutic target in both COPD and asthma; however, the efficacy of pharmaceutical interventions varies between diseases. Furthermore, the nature of some shared clinical features also differs. We provide a narrative review of differences in the nature of T2 inflammation between COPD and asthma, which may partly explain phenotypic differences between diseases. We focus on evidence from studies of pulmonary histopathology, sputum and epithelial gene and protein expression, and response to pharmacological interventions targeted at T2 inflammation.

Of the 251 IT, manufacturing, pharma, engineering, financial and other companies studied, only 40 were providing out-patient department (OPD) benefits in 2019, per the latest report by AON India

Chronic obstructive pulmonary disease, COPD, is a progressive lung disease that makes breathing hard. It can turn fatal if not properly treated. Smoking and exposure to air pollution are considered as some of the main causes of COPD. Some

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Acute exacerbations of chronic obstructive pulmonary disease, or COPD, are associated with significant long-term lung function loss, according to research published online, ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

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Individuals with Severe COPD Encouraged to Inquire About Participation in the Study

On February 27, in Antigua, Guatemala, OPDAT hosted an Operation Regional Shield meeting with prosecutors, investigators, and analysts from Honduras, El Salvador, Guatemala, and Mexico.

On March 4, in Kuala Lumpur, Malaysia, the country’s first Manual on Courtroom Security in Terrorism Cases was presented to the Chair of Malaysia’s National Judicial Security Committee (NJSC) for consideration and adoption.

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A simple method of replacing all text with images in a single level dropdown menu with rollover.

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A dropdown version of the previous multi-line flyout menu

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