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Albert "Al" E. Depew, MSFS, AEP, Featured in the December 2023/January 2024 Issue of Fortune Magazine

Albert "Al" E. Depew, MSFS, AEP, shared his professional achievements and industry expertise in Fortune magazine




msf

Albert "Al" E. Depew, MSFS, AEP, Featured in the December 2023/January 2024 Issue of Forbes magazine

Albert "Al" E. Depew, MSFS, AEP, shared his professional achievements and industry expertise in Forbes magazine





msf

Fast Quantitative Analysis of timsTOF PASEF Data with MSFragger and IonQuant [Technological Innovation and Resources]

Ion mobility brings an additional dimension of separation to LC–MS, improving identification of peptides and proteins in complex mixtures. A recently introduced timsTOF mass spectrometer (Bruker) couples trapped ion mobility separation to TOF mass analysis. With the parallel accumulation serial fragmentation (PASEF) method, the timsTOF platform achieves promising results, yet analysis of the data generated on this platform represents a major bottleneck. Currently, MaxQuant and PEAKS are most used to analyze these data. However, because of the high complexity of timsTOF PASEF data, both require substantial time to perform even standard tryptic searches. Advanced searches (e.g. with many variable modifications, semi- or non-enzymatic searches, or open searches for post-translational modification discovery) are practically impossible. We have extended our fast peptide identification tool MSFragger to support timsTOF PASEF data, and developed a label-free quantification tool, IonQuant, for fast and accurate 4-D feature extraction and quantification. Using a HeLa data set published by Meier et al. (2018), we demonstrate that MSFragger identifies significantly (~30%) more unique peptides than MaxQuant (1.6.10.43), and performs comparably or better than PEAKS X+ (~10% more peptides). IonQuant outperforms both in terms of number of quantified proteins while maintaining good quantification precision and accuracy. Runtime tests show that MSFragger and IonQuant can fully process a typical two-hour PASEF run in under 70 min on a typical desktop (6 CPU cores, 32 GB RAM), significantly faster than other tools. Finally, through semi-enzymatic searching, we significantly increase the number of identified peptides. Within these semi-tryptic identifications, we report evidence of gas-phase fragmentation before MS/MS analysis.




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Signature Global to deliver 16 msf houses over next two years

The real estate developer is targeting collections of ₹3800 crore in the current fiscal year




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Genmab A/S (GNMSF) CEO Jan van de Winkel on Q1 2020 Results - Earnings Call Transcript




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Genmab A/S (GNMSF) CEO Jan van de Winkel on Q1 2020 Results - Earnings Call Transcript




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MSFD implementation: strengths and barriers assessed across European marine regions

There are adequate resources to implement the Marine Strategy Framework Directive (MSFD) in Europe, a recent study concludes. However, more clarity is needed on the roles of different institutions at EU, regional and national levels in implementing the Directive.




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Médecins Sans Frontières (MSF) Awarded 2015 Chatham House Prize

13 October 2015

Médecins Sans Frontières, the medical humanitarian organization, has been awarded the Chatham House Prize 2015 for its life-saving work in combating the outbreak of Ebola in West Africa.

Médecins Sans Frontières (MSF) has been awarded the Chatham House Prize 2015.

The Chatham House Prize is presented annually to the person or organization deemed by members of the Royal Institute of International Affairs to have made the most significant contribution to the improvement of international relations in the previous year.

This year, members voted for MSF in recognition of its work in combating the 2014 Ebola outbreak in West Africa. MSF was among the first groups to respond to the epidemic in March of that year and remained engaged on the ground throughout the crisis, caring for the majority of patients in Liberia, Guinea and Sierra Leone. MSF leaders and staff were persistent and forceful in their action to halt the spread of the epidemic and, as a result, were instrumental in saving thousands of lives. 

Dr Joanne Liu, MSF’s international president, will represent MSF at the Chatham House Prize award ceremony in London where she will be presented with a crystal award and a scroll, signed by Her Majesty The Queen, patron of the institute. Previous recipients of the Prize include former president Lula of Brazil, Burmese democracy campaigner Aung San Suu Kyi, former US secretary of state Hillary Clinton, and Melinda Gates, co-founder of the Bill and Melinda Gates Foundation.

Dr Robin Niblett CMG, director of Chatham House, said: 

'I warmly congratulate Médecins Sans Frontières on being voted the recipient of this year's Chatham House Prize. This is the first time an organization has been awarded the Prize and I am delighted that their vital work has been recognized in this way. MSF led the fight against Ebola by sounding an early alarm on its dangers. It put into place a highly effective operation that saved thousands of lives, and helped prevent a more wide-spread catastrophe, risking and, in some cases, losing the lives of its own staff.'

Dr Joanne Liu, international president of MSF said:

'I am honoured that MSF will be the recipient of this year’s Chatham House Prize and I look forward to accepting this award on behalf of the thousands of people who worked in the Ebola outbreak. This includes the doctors, nurses and logisticians who volunteered from around the world, and the thousands more national staff in Guinea, Liberia, Mali, Nigeria and Sierra Leone who made our work possible. Knowing that they did this while coping with the fear of Ebola in their communities and in the face of incredible stigma makes their contribution even more remarkable. While we continue to work on the ground, our focus is also trying to ensure that next time there is an outbreak, that patients get the care and treatment they need, on time, before it spreads and turns into a killer epidemic. But we all still have a long way to go and it is important that we work together to respond to these challenges and opportunities.'

Members Event

Chatham House Prize 2015: In Conversation with Dr Joanne Liu of Médecins Sans Frontières
13 October 2015 - 17:00 - 18:00

Sponsors

Chatham House gratefully acknowledges the support of our lead sponsor Royal Dutch Shell, and other sponsors AIG, BHP Billiton, Chevron and DTCC.

Nominees

There were three other nominees for the Chatham House Prize 2015:

  • Mahamadou Issoufou, President, Republic of Niger (2011-) 
  • Juan Manuel Santos, President, Republic of Colombia (2010-)
  • Angela Merkel, Chancellor, Federal Republic of Germany (2005-)

About the Chatham House Prize

The annual Chatham House Prize, launched in 2005, is awarded to the person or organization that is deemed by Chatham House members to have made the most significant contribution to the improvement of international relations in the previous year.

The selection process draws on the expertise of Chatham House's research teams and three presidents, who nominate candidates. Our members are then invited to vote for the winner in a ballot.

Further information about the Chatham House Prize




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Important Issues about SMSFs for Family Lawyers - Slides - S Wild.




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MSF-XB11.rar

MSF eXploit Builder is a Windows GUI to build Metasploit Framework exploit modules. It will help you to edit/modify/create/test exploit modules for the Metasploit Framework. Full source release. It includes a built-in fuzzer, a win32 debugger, and a lot of tools used in the process of exploit development.




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Bishop of Chelmsford Stephen Cottrell is named the next Archbishop of York 

Stephen Cottrell, the current Bishop of Chelmsford who has three children with his wife Rebecca (pictured today), a potter, will take over from Dr John Sentamu who stands down in June.




msf

Determination of total and bioavailable of As and Sb in children’s paints using MSFIA system coupled to HG-AFS

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/C9AY02779C, Paper
Dayara Virginia Lino Ávila, Sidnei OLIVEIRA Souza, Victor Cerdà, Rennan Geovanny Oliveira Araujo
In this work, the application of Doehlert design for the optimisation aiming the determination of As and Sb in gouache and tempera children's paints, using multi-syringe flow injection analysis (MSFIA)...
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