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Cooperativa Ceramica d'Imola North America Debuts 5 New Programs

Cooperativa Ceramica d’Imola, North America introduces five new programs under the Imola Ceramica brand known for Italian design and artistry, and spanning multiple segments and formats.




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Jul 26 - Hieromartyrs Hermolaus, Hermippus And Hermocrates and Righteous Martyr Paraskeve




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Holy Hieromartyrs Hermolaus, Hermippus, and Hermocrates at Nicomedia




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Holy Hieromartyrs Hermolaus, Hermippus, and Hermocrates at Nicomedia




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Holy Hieromartyrs Hermolaus, Hermippus, and Hermocrates at Nicomedia




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Holy Hieromartyrs Hermolaus (305), Hermippus, and Hermocrates at Nicomedia




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Holy Hieromartyrs Hermolaus (305), Hermippus, and Hermocrates at Nicomedia

They were priests in Nicomedia; it was Hermolaus who converted St Panteleimon (July 27) to Christ. When St Panteleimon, interrogated by Maximian, was asked who had turned him from the idols, he named Hermolaus. (The Great Horologion notes that it had been revealed to Panteleimon that the time of Hermolaus' martyrdom was near at hand). St Hermolaus was arrested allong with Sts Hermippus and Hermocrates and, when they proclaimed Christ to be the only true God, all were beheaded. St Hermolaus, along with his disciple St Panteleimon, is counted as one of the Unmercenary Physicians.




mola

Holy Hieromartyrs Hermolaus (305), Hermippus, and Hermocrates at Nicomedia

They were priests in Nicomedia; it was Hermolaus who converted St Panteleimon (July 27) to Christ. When St Panteleimon, interrogated by Maximian, was asked who had turned him from the idols, he named Hermolaus. (The Great Horologion notes that it had been revealed to Panteleimon that the time of Hermolaus' martyrdom was near at hand). St Hermolaus was arrested allong with Sts Hermippus and Hermocrates and, when they proclaimed Christ to be the only true God, all were beheaded. St Hermolaus, along with his disciple St Panteleimon, is counted as one of the Unmercenary Physicians.




mola

International Molasses powdered sweetener made from fresh-squeezed cane juice

International Molasses (IM) has introduced CaneRite Panela, an all-natural, free-flowing powder sweetener made from the freshly squeezed juice of the entire sugar cane plant.




mola

Joseph Ryan Smolarz, MD, MBA, Honored for Expertise in the Health Care Industry

Joseph Ryan Smolarz, MD, MBA, is a physician at Virgin Islands Ear, Nose and Throat




mola

We Are Lady Parts: cuatro tipas londinenses musulmanas con un grupo de punk-rock que molan muchísimo

Muchos ejecutivos televisivos ante semejante idea sólo saben decir que no. No hay nadie que la haya visto y no le diga sí. Leer




mola

Aislamiento obligatorio ahora será progresivo con enfoque regional: Molano




mola

Otra vez el ministro Diego Molano metiéndonos en líos diplomáticos, ahora con Rusia: El personaje del día de Melquisedec Torres en La Luciér




mola

Se va “Otoniel”, se queda Molano y todo sigue caro

En este episodio, La Luciérnaga se enciende para hablar de la sorprendente extradición de alias “Otoniel”. También, se cayó la moción de censura contra el ministro de Defensa, Diego Molano, tras el cuestionado operativo en Putumayo.

La Luciérnaga un espacio de humo análisis y opinión de Caracol Radio que acompaña a sus oyentes en el regreso a casa.




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Diego Molano en #SinAnestesia

Escuche el programa de este martes 26 de septiembre. La Luciérnaga, un espacio de humor y opinión de Caracol Radio que acompaña desde hace más de 30 años a sus oyentes en el regreso a casa.




mola

Mamola Petro, salario mínimo y operación éxodo

Escuche el programa de este viernes 22 de diciembre. La Luciérnaga, un espacio de humor y opinión de Caracol Radio que acompaña por más de 30 años a sus oyentes en el regreso a casa.




mola

News24 | Ronald Lamola denies ANC is protecting 'its friend Frelimo' ahead of more protests in Mozambique

International Relations and Cooperation Minister Ronald Lamola threw diplomacy out the window on Tuesday and responded angrily when he was asked whether South Africa and the ANC were "protecting its friend" Frelimo in troubled Mozambique.




mola

Old Town Road [Electronic book] / Chris Molanphy.

Durham : Duke University Press, [2023]




mola

Regulating water decontamination and food safety by a reusable, nano-sized MOF@cotton@chitosan composite through nanomolar detection of the drug nitroxinil and organoarsenic feed additive p-arsanilic acid

Environ. Sci.: Nano, 2024, Advance Article
DOI: 10.1039/D4EN00066H, Paper
Subhrajyoti Ghosh, Debjit Mal, Shyam Biswas
MOF@cotton@chitosan composite for nanomolar fluorescence sensing of nitroxinil drug and p-arsanilic acid in real samples is presented.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mola

Aghori’s self-immolation bid triggers tension in Srikalahasti

Aghori accuses the police of behaving rudely with her, forcing her to take the extreme step




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Self-immolative polydisulfides and their use as nanoparticles for drug delivery systems

RSC Adv., 2024, 14,35568-35577
DOI: 10.1039/D4RA07228F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katharina Völlmecke, Maurice Kramer, Corinna Horky, Oliver Dückmann, Dennis Mulac, Klaus Langer, Dirk Kuckling
Polydisulfide based nanoparticles can be degraded by glutathione (GSH) to deliver hydrophobic drugs.
The content of this RSS Feed (c) The Royal Society of Chemistry




mola

Bifunctional catalysts based on PdZn/ZnO and hierarchical zeolites in the direct synthesis of dimethyl ether from CO-rich syngas: influence of the support and the Zn/Pd molar ratio

Catal. Sci. Technol., 2024, Advance Article
DOI: 10.1039/D4CY00860J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Bing Wang, Nicola Da Roit, Michael Zimmermann, Markus Boese, Thomas Zevaco, Silke Behrens
Pd/Zn-nanoparticles were used as precursors to study the influence of the molar Zn/Pd ratio and hierarchical HZSM-5 zeolites in the syngas-to-dimethyl ether process.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry





mola

Processivity of dextransucrases synthesizing very-high-molar-mass dextran is mediated by sugar-binding pockets in domain V [Glycobiology and Extracellular Matrices]

The dextransucrase DSR-OK from the Gram-positive bacterium Oenococcus kitaharae DSM17330 produces a dextran of the highest molar mass reported to date (∼109 g/mol). In this study, we selected a recombinant form, DSR-OKΔ1, to identify molecular determinants involved in the sugar polymerization mechanism and that confer its ability to produce a very-high-molar-mass polymer. In domain V of DSR-OK, we identified seven putative sugar-binding pockets characteristic of glycoside hydrolase 70 (GH70) glucansucrases that are known to be involved in glucan binding. We investigated their role in polymer synthesis through several approaches, including monitoring of dextran synthesis, affinity assays, sugar binding pocket deletions, site-directed mutagenesis, and construction of chimeric enzymes. Substitution of only two stacking aromatic residues in two consecutive sugar-binding pockets (variant DSR-OKΔ1-Y1162A-F1228A) induced quasi-complete loss of very-high-molar-mass dextran synthesis, resulting in production of only 10–13 kg/mol polymers. Moreover, the double mutation completely switched the semiprocessive mode of DSR-OKΔ1 toward a distributive one, highlighting the strong influence of these pockets on enzyme processivity. Finally, the position of each pocket relative to the active site also appeared to be important for polymer elongation. We propose that sugar-binding pockets spatially closer to the catalytic domain play a major role in the control of processivity. A deep structural characterization, if possible with large-molar-mass sugar ligands, would allow confirming this hypothesis.




mola

Erin Molan calls out anti-vax WAGs for making ‘incredibly dangerous’ comparison

Tune into our new show Fox League Live on Channel 502 Monday to Friday at 6.30pm and on Saturday at 3pm and Sunday at 5pm.




mola

Erin Molan shuts down anti-vaxxer NRL WAG for comparing herself to Holocaust victim Anne Frank

Shanelle Cartwright, the wife of Gold Coast Titans forward Bryce Cartwright, posted the image of the teenage Holocaust victim to her Instagram story on Friday.




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Man addicted to nicotine immolates self




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U.S. shutdown slows Hawaii molasses probe

U.S. authorities have largely suspended their investigation of the molasses spill that fouled Hawaiian waters last month.



  • Wilderness & Resources

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Molasses binder

A binder based predominantly on molasses which incorporates both polymeric and monomeric polycarboxylic acid components to form a composite including both melanoidin and polyester polymeric structures. The binder incorporates the chemical profile of molasses with a mixture of polycarboxylic acids which combines to form a strong and weatherable binder composition which may be used to bind loosely or non-assembled matter.




mola

Blackstrap molasses helped normalize bowel habits


One reader reports success with molasses for normalizing bowel movements.




mola

GOULD, G.: String Quartet / GULDA, F.: String Quartet in F-Sharp Minor (Acies Quartett) (Gramola99028)

Review by Guy Rickards
Gramophone, May 2020




mola

MAHLER, G.: Symphony No. 5 / TCHAIKOVSKY, P.I.: Piano Concerto No. 1 (Live aus der Elbphilharmonie) (SoRyang, Yutaka Sado) (NTSC) (Gramola20004)




mola

Piano Recital: Józsa, Peter - HAYDN, J. / SCHUBERT, F. / CHOPIN, F. / LISZT, F. / BRAHMS, J. (Portrait) (Gramola99213)




mola

HAYDN, J.: 6 Original Canzonettas, Books 1 and 2 / Lieder (Britain's Glory) (Horak, R. Fuller) (Gramola99212)




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Cello Quartet Recital: Kolophonistinnen (Die) - BRAMBÖCK, F. / STRAUSS I, J. / STRAUSS II, J. / SHOSTAKOVICH, D. / TANSMAN, A. (Heldinnenleben) (Gramola99218)




mola

Erin Molan: ‘Marriage is the last thing on our minds’

Erin Molan will never forget her very first day working at the Nine Network. As she sat in the newsroom, intimidated by the powerful environment, a young reporter who was doing her first live cross came up on the television screen.




mola

Erin Molan lifts lid on feud with NRL great Andrew Johns

Erin Molan has put to rest her rumoured feud with rugby league great Andrew Johns.





mola

Grower lathers crops in molasses to protect produce as South Australia endures consecutive frosts

A South Australian citrus grower is lathering his crops in molasses in an attempt to protect the produce from damaging frosts.




mola

People v Molano

(Supreme Court of California) - Affirmed. Automatic death penalty appeal. Defendant convicted of first degree murder with the special circumstances for rape. Jury returned a verdict of death and the court imposed that sentence.




mola

Processivity of dextransucrases synthesizing very-high-molar-mass dextran is mediated by sugar-binding pockets in domain V [Glycobiology and Extracellular Matrices]

The dextransucrase DSR-OK from the Gram-positive bacterium Oenococcus kitaharae DSM17330 produces a dextran of the highest molar mass reported to date (∼109 g/mol). In this study, we selected a recombinant form, DSR-OKΔ1, to identify molecular determinants involved in the sugar polymerization mechanism and that confer its ability to produce a very-high-molar-mass polymer. In domain V of DSR-OK, we identified seven putative sugar-binding pockets characteristic of glycoside hydrolase 70 (GH70) glucansucrases that are known to be involved in glucan binding. We investigated their role in polymer synthesis through several approaches, including monitoring of dextran synthesis, affinity assays, sugar binding pocket deletions, site-directed mutagenesis, and construction of chimeric enzymes. Substitution of only two stacking aromatic residues in two consecutive sugar-binding pockets (variant DSR-OKΔ1-Y1162A-F1228A) induced quasi-complete loss of very-high-molar-mass dextran synthesis, resulting in production of only 10–13 kg/mol polymers. Moreover, the double mutation completely switched the semiprocessive mode of DSR-OKΔ1 toward a distributive one, highlighting the strong influence of these pockets on enzyme processivity. Finally, the position of each pocket relative to the active site also appeared to be important for polymer elongation. We propose that sugar-binding pockets spatially closer to the catalytic domain play a major role in the control of processivity. A deep structural characterization, if possible with large-molar-mass sugar ligands, would allow confirming this hypothesis.




mola

Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome

Guillermo E. Umpierrez
Jan 1, 2002; 15:
Articles




mola

Processivity of dextransucrases synthesizing very-high-molar-mass dextran is mediated by sugar-binding pockets in domain V [Glycobiology and Extracellular Matrices]

The dextransucrase DSR-OK from the Gram-positive bacterium Oenococcus kitaharae DSM17330 produces a dextran of the highest molar mass reported to date (∼109 g/mol). In this study, we selected a recombinant form, DSR-OKΔ1, to identify molecular determinants involved in the sugar polymerization mechanism and that confer its ability to produce a very-high-molar-mass polymer. In domain V of DSR-OK, we identified seven putative sugar-binding pockets characteristic of glycoside hydrolase 70 (GH70) glucansucrases that are known to be involved in glucan binding. We investigated their role in polymer synthesis through several approaches, including monitoring of dextran synthesis, affinity assays, sugar binding pocket deletions, site-directed mutagenesis, and construction of chimeric enzymes. Substitution of only two stacking aromatic residues in two consecutive sugar-binding pockets (variant DSR-OKΔ1-Y1162A-F1228A) induced quasi-complete loss of very-high-molar-mass dextran synthesis, resulting in production of only 10–13 kg/mol polymers. Moreover, the double mutation completely switched the semiprocessive mode of DSR-OKΔ1 toward a distributive one, highlighting the strong influence of these pockets on enzyme processivity. Finally, the position of each pocket relative to the active site also appeared to be important for polymer elongation. We propose that sugar-binding pockets spatially closer to the catalytic domain play a major role in the control of processivity. A deep structural characterization, if possible with large-molar-mass sugar ligands, would allow confirming this hypothesis.




mola

Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome

Guillermo E. Umpierrez
Jan 1, 2002; 15:
Articles




mola

Clinical Outcomes in Patients With Isolated or Combined Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State: A Retrospective, Hospital-Based Cohort Study

OBJECTIVE

Many patients with hyperglycemic crises present with combined features of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). The implications of concomitant acidosis and hyperosmolality are not well known. We investigated hospital outcomes in patients with isolated or combined hyperglycemic crises.

RESEARCH DESIGN AND METHODS

We analyzed admissions data listing DKA or HHS at two academic hospitals. We determined 1) the frequency distributions of HHS, DKA, and combined DKA-HHS (DKA criteria plus elevated effective osmolality); 2) the relationship of markers of severity of illness and clinical comorbidities with 30-day all-cause mortality; and 3) the relationship of hospital complications associated with insulin therapy (hypoglycemia and hypokalemia) with mortality.

RESULTS

There were 1,211 patients who had a first admission with confirmed hyperglycemic crises criteria, 465 (38%) who had isolated DKA, 421 (35%) who had isolated HHS, and 325 (27%) who had combined features of DKA-HHS. After adjustment for age, sex, BMI, race, and Charlson Comorbidity Index score, subjects with combined DKA-HHS had higher in-hospital mortality compared with subjects with isolated hyperglycemic crises (adjusted odds ratio [aOR] 2.7; 95% CI 1.4, 4.9; P = 0.0019). In all groups, hypoglycemia (<40 mg/dL) during treatment was associated with a 4.8-fold increase in mortality (aOR 4.8; 95% CI 1.4, 16.8). Hypokalemia ≤3.5 mEq/L was frequent (55%). Severe hypokalemia (≤2.5 mEq/L) was associated with increased inpatient mortality (aOR 4.9; 95% CI 1.3, 18.8; P = 0.02).

CONCLUSIONS

Combined DKA-HHS is associated with higher mortality compared with isolated DKA or HHS. Severe hypokalemia and severe hypoglycemia are associated with higher hospital mortality in patients with hyperglycemic crises.




mola

Only Petty Criminals Will Be Released to Combat Spread of COVID-19 in Prisons - Lamola

[News24Wire] Only offenders who committed petty crimes will be eligible to be included in the 19 000 inmates who will be released on parole to combat the spread of Covid-19 in prisons.




mola

Layering and structural inheritance controls on fault zone structure in three dimensions: a case study from the northern Molasse Basin, Switzerland

Mechanical heterogeneity of a sedimentary sequence exerts a primary control on the geometry of fault zones and the proportion of offset accommodated by folding. The Wildensbuch Fault Zone in the Swiss Molasse Basin, with a maximum throw of 40 m, intersects a Mesozoic section containing a thick (120 m) clay-dominated unit (Opalinus Clay) over- and underlain by more competent limestone units. Interpretation of a 3D seismic reflection survey indicates that the fault zone formed by upward propagation of an east–west-trending basement structure, through the Mesozoic section, in response to NE–SW Miocene extension. This configuration formed an array of left-stepping normal fault segments above and below the Opalinus Clay. In cross-section a broad monoclinal fold is observed in the Opalinus Clay. Folding, however, is not ubiquitous and occurs in the Opalinus Clay where fault segments above and below are oblique to one another; where they are parallel the fault passes through the Opalinus Clay with little folding. These observations demonstrate that, even in strongly heterogeneous sequences, here a four-fold difference in both Young's modulus and cohesion between layers, the occurrence of folding may depend on the local relationship between fault geometry and applied stress field rather than rheological properties alone.




mola

Molar element ratio analysis of lithogeochemical data: a toolbox for use in mineral exploration and mining

Molar element ratio analysis of element concentrations consists of four basic tools that provide substantial insight into the lithogeochemistry (and mineralogy) of rocks under examination. These tools consist of: (1) conserved element ratio analysis; (2) Pearce element ratio analysis; (3) general element ratio analysis; and (4) lithogeochemical mineral mode analysis. Conserved element ratio analysis is useful in creating a chemostratigraphic model for the host rocks to mineral deposits, whereas Pearce element ratio analysis and general element ratio analysis are primarily used to identify mineralogical and metasomatic controls on rock compositions and to investigate and quantify the extent of the material transfers that formed the host rocks and mineralization. Lithogeochemical mineral mode analysis converts element concentrations into mineral concentrations using a matrix-based change-of-basis operation, allowing lithogeochemical data to be interpreted in terms of mineral modes. It can be used to provide proper names to rocks, an important activity for an exploration geologist because of the implications that rock names have on genetic processes and mineral deposit models.

This paper provides a review of the theoretical foundations of each of these four tools and then illustrates how these techniques have been used in a variety of exploration applications to assist in the search for, evaluation and planning of, and the mining of mineral deposits. Examples include the evaluation of total digestion lithogeochemical datasets from mineral deposits hosted by igneous and sedimentary rocks and formed by hydrothermal and igneous processes. In addition, this paper illustrates a more recent geometallurgical application of these methods, whereby the mineral proportions determined by lithogeochemical mineral mode analysis are used to predict rock properties and obtain the ore body knowledge critical for resource evaluation, mine planning, mining and mine remediation.

Thematic collection: This article is part of the Exploration 17 collection available at: https://www.lyellcollection.org/cc/exploration-17




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Clinical and radiographic evaluation of indirect pulp treatment of young permanent molars using photo-activated oral disinfection versus calcium hydroxide: a randomized controlled pilot trial




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Nanomolar-scale, high throughput chemical synthesis of drug-like molecules

A high throughput, miniaturized chemical synthesis platform could enable rapid discovery of lead compounds.