hybrids In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3674-3694DOI: 10.1039/D4MD00580E, Research ArticleJinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin JinOridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3778-3794DOI: 10.1039/D4MD00281D, Research ArticleCarolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. PilliA novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Equity Derivatives and Hybrids Markets, Models and Methods By search.lib.uiowa.edu Published On :: Location: Electronic Resource- Full Article
hybrids Fabrication of MoS2/rGO hybrids as electrocatalyst for water splitting applications By pubs.rsc.org Published On :: RSC Adv., 2024, 14,12742-12753DOI: 10.1039/D4RA00697F, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Muhammad Shahzeb Khan, Tayyaba Noor, Erum Pervaiz, Naseem Iqbal, Neelam ZamanEnvironmental degradation and energy constraint are important risks to long-term sustainability in the modern world.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Polymeric polyiodo-chlorotellurates(IV): new supramolecular hybrids in halometalate chemistry By pubs.rsc.org Published On :: CrystEngComm, 2024, 26,2018-2024DOI: 10.1039/D4CE00088A, PaperNikita A. Korobeynikov, Andrey N. Usoltsev, Maxim N. Sokolov, Alexander S. Novikov, Sergey A. AdoninReaction between TeO2 and I2 in HCl afforded a series of supramolecular hybrids Cat2{[TeCl6](I2)} (1–5) where diiodine fragments are linked to [TeCl6]2− octahedra via halogen bonds (XB).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Design, synthesis, biological evaluation and molecular docking studies of quinoline-anthranilic acid hybrids as potent anti-inflammatory drugs By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00040D, PaperSidra Siddique, Khalid Hussain, Naureen Shehzadi, Muhammad Arshad, Muhammad Nadeem Arshad, Sadaf Iftikhar, Farhat Saghir, Ayisha Shaukat, Muhammad Sarfraz, Nisar AhmedDespite the high global prevalence, rheumatoid arthritis lacks a satisfactory treatment.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Unravelling Structure - Luminescence Relationship in Two Dimensional Antimony(III) Doped Cadmium (II) Halide Hybrids By pubs.rsc.org Published On :: J. Mater. Chem. C, 2024, Accepted ManuscriptDOI: 10.1039/D4TC03543G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ashwath Kudlu, Dhritismita Sarma, Deep K Das, Alisha Basheer Shamla, Rangarajan Bakthavatsalam, Venkatesha R. Hathwar, Arup Mahata, Janardan KunduLuminescent zero dimensional (0D) antimony halide (Sb-X) hybrids showcase emissive properties (emission peak position; photoluminescence quantum yield-PLQY) that are strongly dependent on the local metal halide geometry/site asymmetry. However, controlling...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Design, synthesis, and biological evaluation of pyrazole–ciprofloxacin hybrids as antibacterial and antibiofilm agents against Staphylococcus aureus By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00623B, Research ArticleOjaswitha Ommi, Priyanka Sudhir Dhopat, Shashikanta Sau, Madhu Rekha Estharla, Srinivas Nanduri, Nitin Pal Kalia, Venkata Madhavi YaddanapudiA series of pyrazole–ciprofloxacin hybrids were designed, synthesized, and tested for antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis, aiming to combat antibiotic resistance.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Design, synthesis, and in vitro and in vivo biological evaluation of triazolopyrimidine hybrids as multitarget directed anticancer agents By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35239-35254DOI: 10.1039/D4RA06704E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Heba A. Adawy, Samar S. Tawfik, Abdullah A. Elgazar, Khalid B. Selim, Fatma E. GodaIn response to the urgent need for new anti-proliferative agents, four novel series of triazolopyrimidine compounds (7a–e, 9a–d, 11a–f, and 13a–e) were synthesized and evaluated for in vitro and in vivo anticancer efficacy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids From luxury SUVs to city-smart hybrids, here’s a quick look at the cars that are turning heads this month By www.thehindu.com Published On :: Fri, 25 Aug 2023 19:25:49 +0530 This month has been unusually busy in the Indian automotive industry with most major players dropping new models. Here’s a roundup of what we drove. Full Article Life & Style
hybrids Tripeptide-dopamine fluorescent hybrids: a coassembly-inspired antioxidative strategy By feeds.rsc.org Published On :: Chem. Commun., 2020, Advance ArticleDOI: 10.1039/D0CC01882A, CommunicationJun Guo, Fan Zheng, Bo Song, Feng ZhangCoassembling peptides with dopamine molecules can construct hybrid nanostructures with a large Stokes shift green fluorescence, which is an effective antioxidative strategy for biomolecules.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Zipcar adds Prius plug-in hybrids By www.mnn.com Published On :: Fri, 28 Jan 2011 16:20:07 +0000 Car sharing service Zipcar will be adding Toyota Prius plug-in hybrids to its fleet. Full Article Transportation
hybrids Millennials like hybrids, women like SUVs and self-driving cars get a collective 'meh' By www.mnn.com Published On :: Fri, 17 Jan 2014 18:20:44 +0000 Two new studies decipher who prefers which kind of car, revealing unexpected attitudes that challenge many assumptions. Full Article Transportation
hybrids UPS adds 200 hybrids to U.S. fleet By www.mnn.com Published On :: Thu, 08 Apr 2010 18:49:43 +0000 Next time you see one of UPS' iconic big brown delivery trucks, look closely because it may be one of the 200 new hybrids hitting the streets of American cities Full Article Transportation
hybrids Detroit Auto Show: BMW's hybrids combine muscle and mileage By www.mnn.com Published On :: Thu, 12 Jan 2012 17:19:41 +0000 BMW is fielding an all-new 3-Series, and with it an ActiveHybrid 3 that offers both zero to 60 in 5.6 seconds and about 37 mpg. Up a notch, there's the ActiveHy Full Article Transportation
hybrids For Europe's new plug-in hybrids, price matters (a lot) By www.mnn.com Published On :: Wed, 02 Jul 2014 18:56:52 +0000 Audi and Volvo will roll out luxury electric cars in the U.S. market early next year. Full Article Transportation
hybrids 4 plug-in hybrids making noise at Detroit Auto Show By www.mnn.com Published On :: Tue, 13 Jan 2015 18:02:18 +0000 Despite $2 a gallon gas, automakers are still going green, and the popularity of the gas-electric range extender format is just one example. Full Article Transportation
hybrids Despite $2 gas, Kia shows off 3 new hybrids at Chicago Auto Show By www.mnn.com Published On :: Sat, 13 Feb 2016 18:06:00 +0000 The all-new Niro is joined by revamped versions of the Optima. Full Article Transportation
hybrids Buck Rogers in 2013: Carbon-neutral e-gas cars and hydraulic hybrids By www.mnn.com Published On :: Mon, 04 Mar 2013 19:16:35 +0000 e-gas cars and hydraulic hybrids Full Article Transportation
hybrids For fire-breathing supercars, hybrids are the future By www.mnn.com Published On :: Mon, 21 Oct 2013 19:07:24 +0000 Aston Martin's chief is bad-mouthing hybrids and thinks his "V-12 is something special." I beg to differ. His cars get dismal fuel economy. Full Article Transportation
hybrids Los Angeles Auto Show preview: Hot hatches, hybrids and electric vehicles By www.mnn.com Published On :: Tue, 01 Dec 2009 21:14:29 +0000 The LA show, opening this week, features some intriguing green concept cars...headed for production. Are you ready for a compact hybrid Lexus, a 170-mpg VW and Full Article Transportation
hybrids Explorer vs Pilot, 2020 Genesis G70 review, Camry vs Sonata Hybrids: What's New @ The Car Connection By www.thecarconnection.com Published On :: Wed, 06 May 2020 11:45:00 -0400 2020 Honda Pilot vs. 2020 Ford Explorer: Compare Crossover SUVs Two of the bestselling three-row SUVs, the 2020 Honda Pilot and 2020 Ford Explorer, go about their family business a bit differently. Pickup trucks outsell cars for the first time, and it may not be temporary The Ford F-150, Ram 1500, and Chevy Silverado have been the best-selling... Full Article Today in Car News
hybrids The Transcriptional Aftermath in Two Independently Formed Hybrids of the Opportunistic Pathogen Candida orthopsilosis By msphere.asm.org Published On :: 2020-05-06T07:29:31-07:00 ABSTRACT Interspecific hybridization can drive evolutionary adaptation to novel environments. The Saccharomycotina clade of budding yeasts includes many hybrid lineages, and hybridization has been proposed as a source for new pathogenic species. Candida orthopsilosis is an emerging opportunistic pathogen for which most clinical isolates are hybrids, each derived from one of at least four independent crosses between the same two parental lineages. To gain insight into the transcriptomic aftermath of hybridization in these pathogens, we analyzed allele-specific gene expression in two independently formed hybrid strains and in a homozygous strain representative of one parental lineage. Our results show that the effect of hybridization on overall gene expression is rather limited, affecting ~4% of the genes studied. However, we identified a larger effect in terms of imbalanced allelic expression, affecting ~9.5% of the heterozygous genes in the hybrids. This effect was larger in the hybrid with more extensive loss of heterozygosity, which may indicate a tendency to avoid loss of heterozygosity in these genes. Consistently, the number of shared genes with allele-specific expression in the two independently formed hybrids was higher than random expectation, suggesting selective retention. Some of the imbalanced genes have functions related to pathogenicity, including zinc transport and superoxide dismutase activities. While it remains unclear whether the observed imbalanced genes play a role in virulence, our results suggest that differences in allele-specific expression may add an additional layer of phenotypic plasticity to traits related to virulence in C. orthopsilosis hybrids. IMPORTANCE How new pathogens emerge is an important question that remains largely unanswered. Some emerging yeast pathogens are hybrids originated through the crossing of two different species, but how hybridization contributes to higher virulence is unclear. Here, we show that hybrids selectively retain gene regulation plasticity inherited from the two parents and that this plasticity affects genes involved in virulence. Full Article
hybrids Genetic structure in hybrids and progenitors provides insight into processes underlying an invasive cattail (<i>Typha</i> × <i>glauca</i>) hybrid zone By feeds.nature.com Published On :: 2020-03-18 Full Article
hybrids Toyota Recalls 3.8 Million Vehicles, Including Prius Hybrids By www.treehugger.com Published On :: Wed, 30 Sep 2009 11:41:15 -0400 Photo: Wikipedia, Public domain 2004 to 2009 Prius Included in Toyota's September 2009 Recall Toyota has just announced a huge recall. About 3.8 million vehicles are included, and that includes the 2004 to 2009 Prius hybrid. Since that's probably a Full Article Transportation
hybrids Kaizen Fail: Toyota Recalls 437,000 Hybrids Worldwide, Mostly 2010 Prius Models By www.treehugger.com Published On :: Tue, 09 Feb 2010 11:45:42 -0500 Photo: Toyota Ouch We all knew it was coming, but now it's official. Toyota has formally filed a voluntary recall for 437,000 hybrid vehicles worldwide. Most of those are third generation Prius hybrids, but they're also recalling the few Prius PHEV out Full Article Business
hybrids Zipcar Stops Renting 2010 Prius Hybrids Until Brake Problems are Fixed By www.treehugger.com Published On :: Wed, 10 Feb 2010 12:11:52 -0500 Apologies for the bad Photoshop job... Photo: Zipcar Logo, Toyota Less Than 1% of Zipcar Fleet, But... I'm pretty sure that many TreeHugger readers are also Zipcar customers (car-sharing in general is booming), and chances are that with that crowd, the Full Article Transportation
hybrids Waymo may get a $465 million tax credit for buying 62,000 Chrysler Pacifica hybrids By www.treehugger.com Published On :: Wed, 06 Jun 2018 08:29:33 -0400 They are going to be autonomous taxis. Is this a good idea? Full Article Transportation
hybrids [ASAP] Design and Synthesis of Cyclometalated Iridium(III) Complexes—Chromophore Hybrids that Exhibit Long-Emission Lifetimes Based on a Reversible Electronic Energy Transfer Mechanism By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT Inorganic ChemistryDOI: 10.1021/acs.inorgchem.0c00363 Full Article
hybrids Unravelling the nucleation, growth, and faceting of magnetite–gold nanohybrids By pubs.rsc.org Published On :: J. Mater. Chem. B, 2020, 8,3886-3895DOI: 10.1039/C9TB02721A, PaperYulia A. Nalench, Igor V. Shchetinin, Alexander S. Skorikov, Pavel S. Mogilnikov, Michael Farle, Alexander G. Savchenko, Alexander G. Majouga, Maxim A. Abakumov, Ulf WiedwaldThe nucleation, growth and faceting of Fe3O4–Au nanoparticles is systematically monitored using liquid probes during reaction. Two consecutive processes are obtained, the growth of Fe3O4 spheres on Au seeds and faceting towards octahedral motifs.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Molecular transport in ionic liquid/nanomembrane hybrids By feeds.rsc.org Published On :: Phys. Chem. Chem. Phys., 2020, 22,9808-9814DOI: 10.1039/D0CP01233E, PaperDaniil Naberezhnyi, Petr DementyevMolecular transport in ultrathin membranes changes upon surface functionalization.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids [ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00669 Full Article
hybrids Nonlinear organic–inorganic halide hybrids containing unprecedented linear [MIX2]− coordination units and quasi-two-dimensional lone pairs By feeds.rsc.org Published On :: Chem. Commun., 2020, 56,4894-4897DOI: 10.1039/D0CC01532F, CommunicationQi Wu, Xian Liu, Yeshuang Du, Chunlin Teng, Fei LiangA first example of monovalent-metal-based hybrid halides [N(CH3)4]MCl2 (M = Ga+, In+) with zero-dimensional configuration containing unprecedented linear [GaCl2]/[InCl2] units have been designed and synthesized.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids An expedient synthesis of new imino-thiazolidinone grafted dispiro-pyrrolidine-oxindole/indeno hybrids via a multicomponent [3+2] cycloaddition reaction in a deep eutectic solvent By feeds.rsc.org Published On :: New J. Chem., 2020, Advance ArticleDOI: 10.1039/D0NJ00801J, PaperRuby Singh, Munna Ram Saini, Diksha Bhardwaj, Aakash SinghA facile and selective synthesis of novel factionalized dispiro-pyrrolidines via a three component [3+2] cycloaddition reaction using a deep eutectic solvent.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Nanohybrids in environmental & biomedical applications / edited by Surender Kumar Sharma By library.mit.edu Published On :: Sun, 2 Feb 2020 06:24:06 EST Online Resource Full Article
hybrids Nitro-graphene oxide in iridium oxide hybrids: electrochemical modulation of N-graphene redox states and charge capacities By pubs.rsc.org Published On :: Mater. Chem. Front., 2020, 4,1421-1433DOI: 10.1039/C9QM00752K, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.E. Pérez, N. M. Carretero, S. Sandoval, A. Fuertes, G. Tobias, N. Casañ-PastorElectrochemical modulation of N-graphene oxide in IrOx hybrids results in an oxidizing range of graphenes and large charge capacities.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Reversible changes in the electronic structure of carbon nanotube-hybrids upon NO2 exposure under ambient conditions By pubs.rsc.org Published On :: J. Mater. Chem. A, 2020, Advance ArticleDOI: 10.1039/D0TA02749A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Filippo Fedi, Oleg Domanov, Hidetsugu Shiozawa, Kazuhiro Yanagi, Paolo Lacovig, Silvano Lizzit, Andrea Goldoni, Thomas Pichler, Paola AyalaSingle-walled carbon nanotubes have enormous potential for gas sensing. This study shows that cluster filling is a key to high sensitivity and it opens the possibility for a very high desorption at ambient temperature.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Correlation between crystal structures and polar (ferroelectric) properties of hybrids of haloantimonates(III) and halobismuthates(III) By pubs.rsc.org Published On :: Inorg. Chem. Front., 2020, Advance ArticleDOI: 10.1039/D0QI00265H, Review ArticleR. Jakubas, M. Rok, K. Mencel, G. Bator, A. Piecha-BisiorekHalogenoantimonates(III) and halogenobismuthates(III) are a highly versatile class of organic–inorganic hybrid materials, applicable in optoelectronics and switchable dielectric devices.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
hybrids Podcast: The rise of skeletons, species-blurring hybrids, and getting rightfully ditched by a taxi By traffic.omny.fm Published On :: Thu, 17 Nov 2016 12:00:00 -0500 This week we chat about why it’s hard to get a taxi to nowhere, why bones came onto the scene some 550 million years ago, and how targeting bacteria’s predilection for iron might make better vaccines, with Online News Editor Catherine Matacic. Plus, Science’s Alexa Billow talks with news writer Elizabeth Pennisi about the way hybrids muck up the concept of species and turn the evolutionary tree into a tangled web. Listen to previous podcasts [Image: Raul González Alegría; Music: Jeffrey Cook] Full Article Scientific Community
hybrids [ASAP] Self-Enhanced Chemiluminescence of Tris(bipyridine) Ruthenium(II) Derivative Nanohybrids: Mechanism Insight and Application for Sensitive Silver Ions Detection By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Analytical ChemistryDOI: 10.1021/acs.analchem.0c00897 Full Article
hybrids [ASAP] Development of Au and 1D Hydroxyapatite Nanohybrids Supported on 2D Boron Nitride Sheets as Highly Efficient Catalysts for Dehydrogenating Glycerol to Lactic Acid By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT ACS Sustainable Chemistry & EngineeringDOI: 10.1021/acssuschemeng.9b06997 Full Article