Bioethicist and Orthodox Christian Wesley J. Smith joins Fr. Barnabas to discuss medical ethics, end of life issues, and societal trending in the world of bioethics.

According to his contemporary, Jerome, Augustine "established anew the ancient Faith." In his early years he was heavily influenced by Manichaeism and afterward by the Neo-Platonism of Plotinus. After his conversion to Christianity and baptism in AD 387, Augustine developed his own approach to philosophy and theology, accommodating a variety of methods and different perspectives. He believed that the grace of Christ was indispensable to human freedom, and he framed the concepts of original sin and just war. -- When the Western Roman Empire was starting to disintegrate, Augustine developed the concept of the Catholic Church as a spiritual City of God (in a book of the same name), distinct from the material Earthly City. His thoughts profoundly influenced the medieval worldview. Augustine's City of God was closely identified with the Church, the community that worshipped God. In the Catholic Church and the Anglican Communion, he is a saint and pre-eminent Doctor of the Church, and the patron of the Augustinian religious order; his memorial is celebrated 28 August, the day of his death. ... Works: Augustine was one of the most prolific Latin authors in terms of surviving works, and the list of his works consists of more than one hundred separate titles. They include apologetic works against the heresies of the Arians, Donatists, Manichaeans and Pelagians, texts on Christian doctrine, notably De Doctrina Christiana (On Christian Doctrine), exegetical works such as commentaries on Book of Genesis, the Psalms and Paul's Letter to the Romans, many sermons and letters, and the Retractationes, a review of his earlier works which he wrote near the end of his life. Apart from those, Augustine is probably best known for his Confessiones (Confessions), which is a personal account of his earlier life, and for De civitate dei (Of the City of God, consisting of 22 books), which he wrote to restore the confidence of his fellow Christians, which was badly shaken by the sack of Rome by the Visigoths in 410. His De trinitate (On the Trinity), in which he developed what has become known as the 'psychological analogy' of the Trinity, is also among his masterpieces, and arguably one of the greatest theological works of all time. He also wrote On Free Choice Of The Will (De libero arbitrio), addressing why God gives humans free will that can be used for evil. ... Influence on St. Thomas Aquinas: For quotations of St. Augustine by St. Thomas Aquinas see Aquinas and the Sacraments and Thought of Thomas Aquinas. On the topic of original sin: Aquinas proposed a more optimistic view of man than that of Augustine in that his conception leaves to the reason, will, and passions of fallen man their natural powers even after the Fall. Influence on Protestant reformers: While in his pre-Pelagian writings Augustine taught that Adam's guilt as transmitted to his descendants much enfeebles, though does not destroy, the freedom of their will, Protestant reformers Martin Luther and John Calvin affirmed that Original Sin completely destroyed liberty (see total depravity). Abortion and ensoulment: Like other Church Fathers such as Athenagoras St Augustine "vigorously condemned the practice of induced abortion" as a crime, in any stage of pregnancy.

Hippolytus of Rome (170 - 235) was the most important 3rd-century theologian in the Christian Church in Rome, where he was probably born. Photios I of Constantinople describes him in his Bibliotheca (cod. 121) as a disciple of Irenaeus, who was said to be a disciple of Polycarp, and from the context of this passage it is supposed that he suggested that Hippolytus himself so styled himself. However, this assertion is doubtful. He came into conflict with the popes of his time and seems to have headed a schismatic group as a rival bishop of Rome. For that reason he is sometimes considered the first Antipope. He opposed the Roman bishops who softened the penitential system to accommodate the large number of new pagan converts. However, he was very probably reconciled to the Church when he died as a martyr. He is the person usually understood to be meant by Saint Hippolytus. Starting in the 4th century, various legends arose about him, identifying him as a priest of the Novatianist Schism or as a soldier converted by Saint Laurence. He has also been confused with another martyr of the same name.

Denver SHRM July 2016 Volunteer Spotlight - Aubrey Whippo - Frontline Source Group Temporary Agency.

He was the pagan jailkeeper who guarded St Laurence (see August 10); seeing his prisoner's holiness and the wonders wrought by him, Hippolytus was convinced of the truth of the Faith and became a Christian. When St Laurence baptized him, he was granted a vision of heaven and said 'I see innocent souls in great joy.' He took Laurence into his own home, and his entire household were baptized, nineteen in all.   When St Laurence was martyred, Hippolytus retrieved his body by night and buried it. He was detected and brought before the Emperor Valerian on the third day after Laurence's death. Despite severe beatings he would not renounce his faith. The Emperor ordered that he be stripped and flayed but, standing naked before the emperor, Hippolytus said 'You have not stripped me, but have begun to clothe me.' Despite all torments, neither Hippolytus nor any of his household would deny Christ. All of his household were slain, one by one, before Hippolytus. Finally Hippolytus himself was bound behind a wild horse and dragged to death.

He was the pagan jailkeeper who guarded St Laurence (see August 10); seeing his prisoner's holiness and the wonders wrought by him, Hippolytus was convinced of the truth of the Faith and became a Christian. When St Laurence baptized him, he was granted a vision of heaven and said 'I see innocent souls in great joy.' He took Laurence into his own home, and his entire household were baptized, nineteen in all.   When St Laurence was martyred, Hippolytus retrieved his body by night and buried it. He was detected and brought before the Emperor Valerian on the third day after Laurence's death. Despite severe beatings he would not renounce his faith. The Emperor ordered that he be stripped and flayed but, standing naked before the emperor, Hippolytus said 'You have not stripped me, but have begun to clothe me.' Despite all torments, neither Hippolytus nor any of his household would deny Christ. All of his household were slain, one by one, before Hippolytus. Finally Hippolytus himself was bound behind a wild horse and dragged to death.

He was the pagan jailkeeper who guarded St Laurence (see August 10); seeing his prisoner's holiness and the wonders wrought by him, Hippolytus was convinced of the truth of the Faith and became a Christian. When St Laurence baptized him, he was granted a vision of heaven and said 'I see innocent souls in great joy.' He took Laurence into his own home, and his entire household were baptized, nineteen in all.   When St Laurence was martyred, Hippolytus retrieved his body by night and buried it. He was detected and brought before the Emperor Valerian on the third day after Laurence's death. Despite severe beatings he would not renounce his faith. The Emperor ordered that he be stripped and flayed but, standing naked before the emperor, Hippolytus said 'You have not stripped me, but have begun to clothe me.' Despite all torments, neither Hippolytus nor any of his household would deny Christ. All of his household were slain, one by one, before Hippolytus. Finally Hippolytus himself was bound behind a wild horse and dragged to death. Our Holy Mother the Empress Irene (Xenia in Monasticism) (12th c.) She was the pious wife of the Emperor John II Comnenus (reigned 1118-1143), but retired into monastic life. She founded the Monastery of the Pantokrator in Constantinople.

He was the pagan jailkeeper who guarded St Laurence (see August 10); seeing his prisoner's holiness and the wonders wrought by him, Hippolytus was convinced of the truth of the Faith and became a Christian. When St Laurence baptized him, he was granted a vision of heaven and said 'I see innocent souls in great joy.' He took Laurence into his own home, and his entire household were baptized, nineteen in all.   When St Laurence was martyred, Hippolytus retrieved his body by night and buried it. He was detected and brought before the Emperor Valerian on the third day after Laurence's death. Despite severe beatings he would not renounce his faith. The Emperor ordered that he be stripped and flayed but, standing naked before the emperor, Hippolytus said 'You have not stripped me, but have begun to clothe me.' Despite all torments, neither Hippolytus nor any of his household would deny Christ. All of his household were slain, one by one, before Hippolytus. Finally Hippolytus himself was bound behind a wild horse and dragged to death. Our Holy Mother the Empress Irene (Xenia in Monasticism) (12th c.) She was the pious wife of the Emperor John II Comnenus (reigned 1118-1143), but retired into monastic life. She founded the Monastery of the Pantokrator in Constantinople.

Fr. Gregory Hallam draws on St. Augustine for his sermon on the Ascension.

We chat to Gavin Adams and Desmonda Cathabel AKA Aladdin and Jasmine.

Loss of megaherbivores such as elephants and hippos can allow woody plants and non-grassy herbs and flowering plants to encroach on grasslands in African national parks, according to a new University of Utah study, published Sept. 12 in Scientific Reports. The study used isotopes in hippopotamus teeth to find a shift in the diet of hippos over the course of a decade in Uganda's Queen Elizabeth National Park following widespread elephant poaching in the 1970s.

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Insurer provides complimentary smart home kit, premium discount to customers.

Baby pygmy hippo Toni’s underwater debut delights Berlin Zoo visitors

Meet Haggis, a newborn pygmy hippo at Edinburgh's zoo

Verve Festival of Poetry and Spoken Word brings top events to the city.

Festivals and photography exhibition set to celebrate the city's poetry and spoken word scene.

Opportunities for West Midlands theatre makers.

Free activities in the Bullring to accompany festive favourite.

Guo-qiang Bi
Dec 15, 1998; 18:10464-10472
Articles

The GluN3A subunit of N-methyl-D-aspartate receptors (NMDARs) plays an established role in synapse development, but its contribution to neural circuits in the adult brain is less clear. Recent work has demonstrated that in select cell populations, GluN3A assembles with GluN1 to form GluN1/GluN3A receptors that are insensitive to glutamate and instead serve as functional excitatory glycine receptors (eGlyRs). Our understanding of these eGlyRs, and how they contribute to intrinsic excitability and synaptic communication within relevant networks of the developing and the mature brain, is only beginning to be uncovered. Here, using male and female mice, we demonstrate that GluN3A subunits are enriched in the adult ventral hippocampus (VH), where they localize to synaptic and extrasynaptic sites and can assemble as functional eGlyRs on CA1 pyramidal cells. GluN3A expression was barely detectable in the adult dorsal hippocampus (DH). We also observed a high GluN2B content in the adult VH, characterized by slow NMDAR current decay kinetics and a high sensitivity to the GluN2B-containing NMDAR antagonist ifenprodil. Interestingly, the GluN2B enrichment in the adult VH was dependent on GluN3A as GluN3A deletion accelerated NMDAR decay and reduced ifenprodil sensitivity in the VH, suggesting that GluN3A expression can regulate the balance of conventional NMDAR subunit composition at synaptic sites. Lastly, we found that GluN3A knock-out also enhanced both NMDAR-dependent calcium influx and NMDAR-dependent long-term potentiation in the VH. Together, these data reveal a novel role for GluN3A and eGlyRs in the control of ventral hippocampal circuits in the mature brain.

We used virus-mediated anterograde and retrograde tracing, optogenetic modulation, immunostaining, in situ hybridization, and patch-clamp recordings in acute brain slices to study the release mechanism and μ-opioid modulation of the dual glutamatergic/GABAergic inputs from the ventral tegmental area and supramammillary nucleus to the granule cells of the dorsal hippocampus of male and female mice. In keeping with previous reports showing that the two transmitters are released by separate active zones within the same terminals, we found that the short-term plasticity and pharmacological modulation of the glutamatergic and GABAergic currents are indistinguishable. We further found that glutamate and GABA release at these synapses are both virtually completely mediated by N- and P/Q-type calcium channels. We then investigated μ-opioid modulation of these synapses and found that activation of μ-opioid receptors (MORs) strongly inhibits the glutamate and GABA release, mostly through inhibition of presynaptic N-type channels. However, the modulation by MORs of these dual synapses is complex, as it likely includes also a disinhibition due to downmodulation of local GABAergic interneurons which make direct axo-axonic contacts with the dual glutamatergic/GABAergic terminals. We discuss how this opioid modulation may enhance LTP at the perforant path inputs, potentially contributing to reinforce memories of drug-associated contexts.

Plasticity in the subcortical motor basal ganglia–thalamo–cerebellar network plays a key role in the acquisition and control of long-term memory for new procedural skills, from the formation of population trajectories controlling trained motor skills in the striatum to the adaptation of sensorimotor maps in the cerebellum. However, recent findings demonstrate the involvement of a wider cortical and subcortical brain network in the consolidation and control of well-trained actions, including a brain region traditionally associated with declarative memory—the hippocampus. Here, we probe which role these subcortical areas play in skilled motor sequence control, from sequence feature selection during planning to their integration during sequence execution. An fMRI dataset (N = 24; 14 females) collected after participants learnt to produce four finger press sequences entirely from memory with high movement and timing accuracy over several days was examined for both changes in BOLD activity and their informational content in subcortical regions of interest. Although there was a widespread activity increase in effector-related striatal, thalamic, and cerebellar regions, in particular during sequence execution, the associated activity did not contain information on the motor sequence identity. In contrast, hippocampal activity increased during planning and predicted the order of the upcoming sequence of movements. Our findings suggest that the hippocampus preorders movements for skilled action sequences, thus contributing to the higher-order control of skilled movements that require flexible retrieval. These findings challenge the traditional taxonomy of episodic and procedural memory and carry implications for the rehabilitation of individuals with neurodegenerative disorders.

The precise regulation of Ca²⁺ signals plays a crucial role in the physiological functions of neurons. Here, we investigated the rapid effect of glucocorticoids on Ca²⁺ signals in cultured hippocampal neurons from both female and male rats. In cultured hippocampal neurons, glucocorticoids inhibited the spontaneous somatic Ca²⁺ spikes generated by Kv2.1-organized Ca²⁺ microdomains. Furthermore, glucocorticoids rapidly reduced the cell surface expressions of Kv2.1 and Ca_V1.2 channels in hippocampal neurons. In HEK293 cells transfected with Kv2.1 alone, glucocorticoids significantly reduced the surface expression of Kv2.1 with little effect on K⁺ currents. In HEK293 cells transfected with Ca_V1.2 alone, glucocorticoids inhibited Ca_V1.2 currents but had no effect on the cell surface expression of Ca_V1.2. Notably, in the presence of wild-type Kv2.1, glucocorticoids caused a decrease in the surface expression of Ca_V1.2 channels in HEK293 cells. However, this effect was not observed in the presence of nonclustering Kv2.1S586A mutant channels. Live-cell imaging showed that glucocorticoids rapidly decreased Kv2.1 clusters on the plasma membrane. Correspondingly, Western blot results indicated a significant increase in the cytoplasmic level of Kv2.1, suggesting the endocytosis of Kv2.1 clusters. Glucocorticoids rapidly decreased the intracellular cAMP concentration and the phosphorylation level of PKA in hippocampal neurons. The PKA inhibitor H89 mimicked the effect of glucocorticoids on Kv2.1, while the PKA agonist forskolin abrogated the effect. In conclusion, glucocorticoids rapidly suppress Ca_V1.2-mediated Ca²⁺ signals in hippocampal neurons by promoting the endocytosis of Kv2.1 channel clusters through reducing PKA activity.

Four decades ago, Pablo Escobar brought to his Medellín hideaway four hippopotamuses, the centerpieces of a menagerie that included llamas, cheetahs, lions, tigers, ostriches and other exotic fauna. After Colombian police shot Escobar dead in December 1993, veterinarians removed the animals—except the hippos, which were deemed too dangerous to approach. The hippos fled to the nearby Magdalena River and multiplied.  Today, the descendants of Escobar’s hippos are believed to number nearly 200. Their uncontrolled growth threatens the region’s fragile waterways. Smithsonian contributor Joshua Hammer joins us to recount this strange history and explain why Colombian conservationists have embarked upon an unusual program to sterilize these hippos in the wild via “invasive surgical castration,” a procedure that is, as he has written (https://www.smithsonianmag.com/science-nature/pablo-escobar-abandoned-hippos-wreaking-havoc-colombian-jungle-180984494/) for Smithsonian magazine, “medically complicated, expensive and sometimes dangerous for hippos as well as for the people performing it.” Then, ecologist Rebecca Lewison tells us how her long-term study of hippo populations in Africa offers hints of how these creatures will continue to alter the Colombian ecosystem—and what authorities can do about it. Let us know what you think of our show, and how we can make it better, by completing our There's More to That listener survey here (https://docs.google.com/forms/d/e/1FAIpQLSfS90zjBZ2oGa9JxVa-R5affKcOHaR2-ib1_KZeWm3HDQXJIA/viewform) . Read Josh Hammer's Smithsonian story about Escobar's hippos and their descendants here (https://www.smithsonianmag.com/science-nature/pablo-escobar-abandoned-hippos-wreaking-havoc-colombian-jungle-180984494/) . Learn more about Rebecca Lewison and her work here (https://cmi.sdsu.edu/rebecca-lewison/) . Find prior episodes of our show here (https://www.smithsonianmag.com/podcast/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Rye Dorsey, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Fact-checking by Stephanie Abramson. Episode artwork by Emily Lankiewicz  Music by APM Music.

The baby pygmy hippopotamus in a Thailand zoo has taken the internet by storm, and keepers hope she will help gain momentum for conservation efforts

Born October 30 to parents Gloria and Otto at the Edinburgh Zoo in Scotland, the hippo is already gaining popularity, following in the footsteps of viral sensation Moo Deng

Memory formation is contingent on molecular and structural changes in neurons in response to learning stimuli—a process known as neuronal plasticity. The initiation step of mRNA translation is a gatekeeper of long-term memory by controlling the production of plasticity-related proteins in the brain. The mechanistic target of rapamycin complex 1 (mTORC1) controls mRNA translation, mainly through phosphorylation of the eukaryotic initiation factor 4E (eIF4E)-binding proteins (4E-BPs) and ribosomal protein S6 kinases (S6Ks). mTORC1 signaling decreases throughout brain development, starting from the early postnatal period. Here, we discovered that in mice, the age-dependent decrease in mTORC1 signaling occurs selectively in excitatory but not inhibitory neurons. Using a gene conditional knockout (cKO) strategy, we demonstrate that either up- or downregulating the mTORC1-4E-BP2 axis in GAD65 inhibitory interneurons, but not excitatory neurons, results in long-term object recognition and object location memory deficits. Our data indicate that the mTORC1 pathway in inhibitory but not excitatory neurons plays a key role in memory formation.

Jibit George, the young filmmaker who made his directorial debut with the recent movie Kozhipporu, passed away. The 31-year-old breathed his last due to cardiac arrest on May 9, 2020 evening. According to the reports, Jibit George was suffering from chest

Jibit George, the young filmmaker who made his directorial debut with the recent movie Kozhipporu, passed away. The 31-year-old breathed his last due to cardiac arrest on May 9, 2020 evening. According to the reports, Jibit George was suffering from chest

Scott J. Neal, Qingxiang Zhou, and Francesca Pignoni

The specification of organs, tissues and cell types results from cell fate restrictions enacted by nuclear transcription factors under the control of conserved signaling pathways. The progenitor epithelium of the Drosophila compound eye, the eye imaginal disc, is a premier model for the study of such processes. Early in development, apposing cells of the eye disc are established as either retinal progenitors or support cells of the peripodial epithelium (PE), in a process whose genetic and mechanistic determinants are poorly understood. We have identified Protein Phosphatase 2A (PP2A), and specifically a STRIPAK-PP2A complex that includes the scaffolding and substrate-specificity components Cka, Strip and SLMAP, as a critical player in the retina-PE fate choice. We show that these factors suppress ectopic retina formation in the presumptive PE and do so via the Hippo signaling axis. STRIPAK-PP2A negatively regulates Hpo kinase, and consequently its substrate Wts, to release the transcriptional co-activator Yki into the nucleus. Thus, a modular higher-order PP2A complex refines the activity of this general phosphatase to act in a precise specification of cell fate.

Pablo Escobar’s legacy of mayhem continues by way of a thriving population of giant African mammals.

Olive Oil Organically Grown and Pure Enough to Carry the Name of the Father of Medicine

Rakesh Khurana, Harvard Business School professor.

Augmented reality used to bring the stories behind the portraits to life.

Zookeepers in Adelaide are farewelling one of their star attractions — the much-loved hippopotamus Brutus, who was euthanased this morning at the ripe old age of 54.

Scientists published the first assessment of the impact that invasive hippos imported by drug lord Pablo Escobar are having on Colombian aquatic ecosystems. The hippos are changing the area's water quality by importing large amounts of nutrients and organic material from the surrounding landscape.

Contes de fées aux enfants - Hippocampus l'hippocampe.

Hippo and Crocodile CruiseToday the VESA group got the opportunity to enjoy a hippo and crocodile cruise along Lake St. Lucia. St. Lucia estuary park is home to around 1200 Nile Crocodiles and 800 hippopotamus. I find hippos intimidating as the

Hippo pathway signaling limits cell growth and proliferation and maintains the stem-cell niche. These cellular events result from the coordinated activity of a core kinase cassette that is regulated, in part, by interactions involving Hippo, Salvador, and dRassF. These interactions are mediated by a conserved coiled-coil domain, termed SARAH, in each of these proteins. SARAH domain–mediated homodimerization of Hippo kinase leads to autophosphorylation and activation. Paradoxically, SARAH domain–mediated heterodimerization between Hippo and Salvador enhances Hippo kinase activity in cells, whereas complex formation with dRassF inhibits it. To better understand the mechanism by which each complex distinctly modulates Hippo kinase and pathway activity, here we biophysically characterized the entire suite of SARAH domain–mediated complexes. We purified the three SARAH domains from Drosophila melanogaster and performed an unbiased pulldown assay to identify all possible interactions, revealing that isolated SARAH domains are sufficient to recapitulate the cellular assemblies and that Hippo is a universal binding partner. Additionally, we found that the Salvador SARAH domain homodimerizes and demonstrate that this interaction is conserved in Salvador's mammalian homolog. Using native MS, we show that each of these complexes is dimeric in solution. We also measured the stability of each SARAH domain complex, finding that despite similarities at both the sequence and structural levels, SARAH domain complexes differ in stability. The identity, stoichiometry, and stability of these interactions characterized here comprehensively reveal the nature of SARAH domain–mediated complex formation and provide mechanistic insights into how SARAH domain–mediated interactions influence Hippo pathway activity.

Hippo pathway signaling limits cell growth and proliferation and maintains the stem-cell niche. These cellular events result from the coordinated activity of a core kinase cassette that is regulated, in part, by interactions involving Hippo, Salvador, and dRassF. These interactions are mediated by a conserved coiled-coil domain, termed SARAH, in each of these proteins. SARAH domain–mediated homodimerization of Hippo kinase leads to autophosphorylation and activation. Paradoxically, SARAH domain–mediated heterodimerization between Hippo and Salvador enhances Hippo kinase activity in cells, whereas complex formation with dRassF inhibits it. To better understand the mechanism by which each complex distinctly modulates Hippo kinase and pathway activity, here we biophysically characterized the entire suite of SARAH domain–mediated complexes. We purified the three SARAH domains from Drosophila melanogaster and performed an unbiased pulldown assay to identify all possible interactions, revealing that isolated SARAH domains are sufficient to recapitulate the cellular assemblies and that Hippo is a universal binding partner. Additionally, we found that the Salvador SARAH domain homodimerizes and demonstrate that this interaction is conserved in Salvador's mammalian homolog. Using native MS, we show that each of these complexes is dimeric in solution. We also measured the stability of each SARAH domain complex, finding that despite similarities at both the sequence and structural levels, SARAH domain complexes differ in stability. The identity, stoichiometry, and stability of these interactions characterized here comprehensively reveal the nature of SARAH domain–mediated complex formation and provide mechanistic insights into how SARAH domain–mediated interactions influence Hippo pathway activity.

Hippo pathway signaling limits cell growth and proliferation and maintains the stem-cell niche. These cellular events result from the coordinated activity of a core kinase cassette that is regulated, in part, by interactions involving Hippo, Salvador, and dRassF. These interactions are mediated by a conserved coiled-coil domain, termed SARAH, in each of these proteins. SARAH domain–mediated homodimerization of Hippo kinase leads to autophosphorylation and activation. Paradoxically, SARAH domain–mediated heterodimerization between Hippo and Salvador enhances Hippo kinase activity in cells, whereas complex formation with dRassF inhibits it. To better understand the mechanism by which each complex distinctly modulates Hippo kinase and pathway activity, here we biophysically characterized the entire suite of SARAH domain–mediated complexes. We purified the three SARAH domains from Drosophila melanogaster and performed an unbiased pulldown assay to identify all possible interactions, revealing that isolated SARAH domains are sufficient to recapitulate the cellular assemblies and that Hippo is a universal binding partner. Additionally, we found that the Salvador SARAH domain homodimerizes and demonstrate that this interaction is conserved in Salvador's mammalian homolog. Using native MS, we show that each of these complexes is dimeric in solution. We also measured the stability of each SARAH domain complex, finding that despite similarities at both the sequence and structural levels, SARAH domain complexes differ in stability. The identity, stoichiometry, and stability of these interactions characterized here comprehensively reveal the nature of SARAH domain–mediated complex formation and provide mechanistic insights into how SARAH domain–mediated interactions influence Hippo pathway activity.

Paris : Germer-Bailliere, 1856-1857.

Rockville, Maryland : National Institute on Drug Abuse, 1988.

WD Knowles
Nov 1, 1981; 1:1236-1241
Articles