evaluation

New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation

RSC Med. Chem., 2024, 15,3759-3777
DOI: 10.1039/D4MD00498A, Research Article
Lucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. Enriz
A diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.
The content of this RSS Feed (c) The Royal Society of Chemistry




evaluation

Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation

RSC Med. Chem., 2024, 15,3778-3794
DOI: 10.1039/D4MD00281D, Research Article
Carolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. Pilli
A novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




evaluation

Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation

RSC Med. Chem., 2024, 15,3880-3888
DOI: 10.1039/D4MD00414K, Research Article
Phuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. Vo
Novel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.
The content of this RSS Feed (c) The Royal Society of Chemistry




evaluation

Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABAA receptors

RSC Adv., 2024, 14,36352-36369
DOI: 10.1039/D4RA07074G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Mingxing Qian, Yuanjian Xu, Hong-Jin Shu, Zi-Wei Chen, Lei Wang, Charles F. Zorumski, Alex S. Evers, Steven Mennerick, Douglas F. Covey
Photoaffinity labels (PALs) for sulfated steroid binding sites on GABAA and NMDA receptors. The PALs have varying profiles of positive and negative modulatory (PAM and NAM) actions.
The content of this RSS Feed (c) The Royal Society of Chemistry




evaluation

Evaluation and optimization of acid processing procedures for the extraction of conodont elements from calcareous rock

Gallotta, C; Gouwy, S A; Komaromi, L. Geological Survey of Canada, Open File 8792, 2021, 50 pages, https://doi.org/10.4095/328273
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_328273.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_328273.jpg" title="Geological Survey of Canada, Open File 8792, 2021, 50 pages, https://doi.org/10.4095/328273" height="150" border="1" /></a>




evaluation

Evaluation of automatic borehole-log identification, selection, and data capture from PDF files

Amini, A; Benoit, N; Russell, H A J. Geological Survey of Canada, Open File 9065, 2023, 17 pages, https://doi.org/10.4095/332258
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332258.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332258.jpg" title="Geological Survey of Canada, Open File 9065, 2023, 17 pages, https://doi.org/10.4095/332258" height="150" border="1" /></a>




evaluation

Correction: Design, synthesis, pharmacological evaluation, and in silico studies of the activity of novel spiro pyrrolo[3,4-d]pyrimidine derivatives

RSC Adv., 2024, 14,36351-36351
DOI: 10.1039/D4RA90128B, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Abdullah Y. A. Alzahrani, Wesam S. Shehab, Asmaa H. Amer, Mohamed G. Assy, Samar M. Mouneir, Maged Abdelaziz, Atef M. Abdel Hamid
The content of this RSS Feed (c) The Royal Society of Chemistry




evaluation

An OCR Free Method for Word Spotting in Printed Documents: the Evaluation of Different Feature Sets

An OCR free word spotting method is developed and evaluated under a strong experimental protocol. Different feature sets are evaluated under the same experimental conditions. In addition, a tuning process in the document segmentation step is proposed which provides a significant reduction in terms of processing time. For this purpose, a complete OCR-free method for word spotting in printed documents was implemented, and a document database containing document images and their corresponding ground truth text files was created. A strong experimental protocol based on 800 document images allows us to compare the results of the three feature sets used to represent the word image.




evaluation

The Synthesis of LSE Classifiers: From Representation to Evaluation

This work presents a first approach to the synthesis of Spanish Sign Language's (LSE) Classifier Constructions (CCs). All current attempts at the automatic synthesis of LSE simply create the animations corresponding to sequences of signs. This work, however, includes the synthesis of the LSE classification phenomena, defining more complex elements than simple signs, such as Classifier Predicates, Inflective CCs and Affixal classifiers. The intelligibility of our synthetic messages was evaluated by LSE natives, who reported a recognition rate of 93% correct answers.




evaluation

Algorithms for the Evaluation of Ontologies for Extended Error Taxonomy and their Application on Large Ontologies

Ontology evaluation is an integral and important part of the ontology development process. Errors in ontologies could be catastrophic for the information system based on those ontologies. As per our experiments, the existing ontology evaluation systems were unable to detect many errors (like, circulatory error in class and property hierarchy, common class and property in disjoint decomposition, redundancy of sub class and sub property, redundancy of disjoint relation and disjoint knowledge omission) as defined in the error taxonomy. We have formulated efficient algorithms for the evaluation of these and other errors as per the extended error taxonomy. These algorithms are implemented (named as OntEval) and the implementations are used to evaluate well-known ontologies including Gene Ontology (GO), WordNet Ontology and OntoSem. The ontologies are indexed using a variant of already proposed scheme Ontrel. A number of errors and warnings in these ontologies have been discovered using the OntEval. We have also reported the performance of our implementation, OntEval.




evaluation

Risk evaluation method of electronic bank investment based on random forest

Aiming at the problems of high error rate, low evaluation accuracy and low investment return in traditional methods, a random forest-based e-bank investment risk evaluation method is proposed. First, establish a scientific e-bank investment risk evaluation index system. Then, G1-COWA combined weighting method is used to calculate the weights of each index. Finally, the e-bank investment risk evaluation index data is taken as the input vector, and the e-bank investment risk evaluation result is taken as the output vector. The random forest model is established and the result of e-banking investment risk evaluation is obtained. The experimental results show that the maximum relative error rate of this method is 4.32%, the evaluation accuracy range is 94.5~98.1%, and the maximum return rate of e-banking investment is 8.32%. It shows that this method can accurately evaluate the investment risk of electronic banking.




evaluation

Evaluation on stock market forecasting framework for AI and embedded real-time system

Since its birth, the stock market has received widespread attention from many scholars and investors. However, there are many factors that affect stock prices, including the company's own internal factors and the impact of external policies. The extent and manner of fundamental impacts also vary, making stock price predictions very difficult. Based on this, this article first introduces the research significance of the stock market prediction framework, and then conducts academic research and analysis on two key sentences of stock market prediction and artificial intelligence in stock market prediction. Then this article proposes a constructive algorithm theory, and finally conducts a simulation comparison experiment and summarises and discusses the experiment. Research results show that the neural network prediction method is more effective in stock market prediction; the minimum training rate is generally 0.9; the agency's expected dilution rate and the published stock market dilution rate are both around 6%.




evaluation

Using Wikis to Enhance Website Peer Evaluation in an Online Website Development Course: An Exploratory Study




evaluation

Self-regulated Mobile Learning and Assessment: An Evaluation of Assessment Interfaces




evaluation

Teaching Quality Evaluation: Online vs. Manually, Facts and Myths

Aim/Purpose: This study aimed to examine whether there is a difference between manual feedback and online feedback with regard to feedback quality, respondents’ percentage, reliability and the amount of verbal comments written by students. Background: The quality of teaching is an important component of academic work. There are various methods for testing the quality of teaching; one of these methods is through students’ feedback. Methodology: This study used a quantitative approach, including the quantification of qualitative verbal data collected through an open question in the questionnaire. A sample of 180 courses was randomly chosen, 90 courses were evaluated manually and 90 were evaluated online. The number of students ranges from 7 to 60 students per course. In total 4678 students participated in the study. Contribution: The findings show that there is almost an identical pattern of feedback of manual and online course teaching evaluation. These findings encourage a continued use of this evaluation method. Findings: No significant differences were found between manual feedback and online feedback in the students’ evaluation of the lecturer/course. The percentage of respondents was significantly higher in the manual feedback than in the online feedback. The number of qualitative comments was significantly greater in the online feedback than in the manual feedback. Impact on Society: The findings of this study refute the claims with regard to the unreliability of an online teaching evaluation. These findings reflect the advantages of using online feedback, such as cost savings, granting more time to students in order to provide feedback, and reducing disturbance during lectures. Future Research: The gender aspect was not taken into account in the study. Therefore, we recommend conducting a follow-up study that will examine gender differences in directions of- difference between male and female lecturers, and differences between male and female students in teaching evaluation.




evaluation

Evaluation criteria for information quality research

Evaluation of research artefacts (such as models, frameworks and methodologies) is essential to determine their quality and demonstrate worth. However, in the information quality (IQ) research domain there is no existing standard set of criteria available for researchers to use to evaluate their IQ artefacts. This paper therefore describes our experience of selecting and synthesising a set of evaluation criteria used in three related research areas of information systems (IS), software products (SP) and conceptual models (CM), and analysing their relevance to different types of IQ research artefact. We selected and used a subset of these criteria in an actual evaluation of an IQ artefact to test whether they provide any benefit over a standard evaluation. The results show that at least a subset of the criteria from the other domains of IS, SP and CM are relevant for IQ artefact evaluations, and the resulting set of criteria, most importantly, enabled a more rigorous and systematic selection of what to evaluate.




evaluation

Application of artificial intelligence in enterprise human resource management and employee performance evaluation

With the rapid development of Artificial Intelligence (AI) technology, significant breakthroughs have been made in its application in many fields. Especially, in the field of enterprise human resource management and employee performance evaluation, AI has demonstrated its powerful ability to optimise and improve performance. This study explores the application of AI in enterprise human resource management and how to use AI to evaluate employee performance. The research includes analysing and comparing existing AI-driven human resource management models, evaluating how AI can help improve employee performance and leadership styles, and designing and developing human resource management computer systems for enterprise employees. Through empirical research and case analysis, this study proposes a new AI-optimised employee performance evaluation model and explores its application and effect in practice. In general, the application of AI can improve the efficiency and accuracy of enterprise human resource management, and provide new possibilities for employee performance evaluation. At present, artificial intelligence technology has been widely used in various fields of daily life, especially in corporate human resource management, providing better support for the development of enterprises.




evaluation

Evaluation method for the effectiveness of online course teaching reform in universities based on improved decision tree

Aiming at the problems of long evaluation time and poor evaluation accuracy of existing evaluation methods, an improved decision tree-based evaluation method for the effectiveness of college online course teaching reform is proposed. Firstly, the teaching mode of college online course is analysed, and an evaluation system is constructed to ensure the applicability of the evaluation method. Secondly, AHP entropy weight method is used to calculate the weights of evaluation indicators to ensure the accuracy and authority of evaluation results. Finally, the evaluation model based on decision tree algorithm is constructed and improved by fuzzy neural network to further optimise the evaluation results. The parameters of fuzzy neural network are adjusted and gradient descent method is used to optimise the evaluation results, so as to effectively evaluate the effect of college online course teaching reform. Through experiments, the evaluation time of the method is less than 5 ms, and the evaluation accuracy is more than 92.5%, which shows that the method is efficient and accurate, and provides an effective evaluation means for the teaching reform of online courses in colleges and universities.




evaluation

Evaluation method of teaching reform quality in colleges and universities based on big data analysis

Research on the quality evaluation of teaching reforms plays an important role in promoting improvements in teaching quality. Therefore, an evaluation method of teaching reform quality in colleges and universities based on big data analysis is proposed. A multivariate logistic model is used to select the evaluation indicators for the quality evaluation of teaching reforms in universities. And clustering and cleaning of the evaluation indicator data are performed through big data analysis. The evaluation indicator data is used as input vectors, and the results of the teaching reform quality evaluation are used as output vectors. A support vector machine model based on the whale algorithm is built to obtain the relevant evaluation results. Experimental results show that the proposed method achieves a minimum recall rate of 98.7% for evaluation indicator data, the minimum data processing time of 96.3 ms, the accuracy rate consistently above 97.1%.




evaluation

A method for evaluating the quality of teaching reform based on fuzzy comprehensive evaluation

In order to improve the comprehensiveness of evaluation results and reduce errors, a teaching reform quality evaluation method based on fuzzy comprehensive evaluation is proposed. Firstly, on the premise of meeting the principles of indicator selection, factor analysis is used to construct an evaluation indicator system. Then, calculate the weights of various evaluation indicators through fuzzy entropy, establish a fuzzy evaluation matrix, and calculate the weight vector of evaluation indicators. Finally, the fuzzy cognitive mapping method is introduced to improve the fuzzy comprehensive evaluation method, obtaining the final weight of the evaluation indicators. The weight is multiplied by the fuzzy evaluation matrix to obtain the comprehensive evaluation result. The experimental results show that the maximum relative error of the proposed method's evaluation results is about 2.0, the average comprehensive evaluation result is 92.3, and the determination coefficient is closer to 1, verifying the application effect of this method.




evaluation

An evaluation of English distance information teaching quality based on decision tree classification algorithm

In order to overcome the problems of low evaluation accuracy and long evaluation time in traditional teaching quality evaluation methods, a method of English distance information teaching quality evaluation based on decision tree classification algorithm is proposed. Firstly, construct teaching quality evaluation indicators under different roles. Secondly, the information gain theory in decision tree classification algorithm is used to divide the attributes of teaching resources. Finally, the rough set theory is used to calculate the index weight and establish the risk evaluation index factor set. The result of teaching quality evaluation is obtained through fuzzy comprehensive evaluation method. The experimental results show that the accuracy rate of the teaching quality evaluation of this method can reach 99.2%, the recall rate of the English information teaching quality evaluation is 99%, and the time used for the English distance information teaching quality evaluation of this method is only 8.9 seconds.




evaluation

Quantitative evaluation method of ideological and political teaching achievements based on collaborative filtering algorithm

In order to overcome the problems of large error, low evaluation accuracy and long evaluation time in traditional evaluation methods of ideological and political education, this paper designs a quantitative evaluation method of ideological and political education achievements based on collaborative filtering algorithm. First, the evaluation index system is constructed to divide the teaching achievement evaluation index data in a small scale; then, the quantised dataset is determined and the quantised index weight is calculated; finally, the collaborative filtering algorithm is used to generate a set with high similarity, construct a target index recommendation list, construct a quantitative evaluation function and solve the function value to complete the quantitative evaluation of teaching achievements. The results show that the evaluation error of this method is only 1.75%, the accuracy can reach 98%, and the time consumption is only 2.0 s, which shows that this method can improve the quantitative evaluation effect.




evaluation

The performance evaluation of teaching reform based on hierarchical multi-task deep learning

The research goal is to solve the problems of low accuracy and long time existing in traditional teaching reform performance evaluation methods, a performance evaluation method of teaching reform based on hierarchical multi-task deep learning is proposed. Under the principle of constructing the evaluation index system, the evaluation indicator system should be constructed. The weight of the evaluation index is calculated through the analytic hierarchy process, and the calculation result of the evaluation weight is taken as the model input sample. A hierarchical multi-task deep learning model for teaching reform performance evaluation is built, and the final teaching reform performance score is obtained. Through relevant experiments, it is proved that compared with the experimental comparison method, this method has the advantages of high evaluation accuracy and short time, and can be further applied in relevant fields.




evaluation

Research on evaluation method of e-commerce platform customer relationship based on decision tree algorithm

In order to overcome the problems of poor evaluation accuracy and long evaluation time in traditional customer relationship evaluation methods, this study proposes a new customer relationship evaluation method for e-commerce platform based on decision tree algorithm. Firstly, analyse the connotation and characteristics of customer relationship; secondly, the importance of customer relationship in e-commerce platform is determined by using decision tree algorithm by selecting and dividing attributes according to the information gain results. Finally, the decision tree algorithm is used to design the classifier, the weighted sampling method is used to obtain the training samples of the base classifier, and the multi-period excess income method is used to construct the customer relationship evaluation function to achieve customer relationship evaluation. The experimental results show that the accuracy of the customer relationship evaluation results of this method is 99.8%, and the evaluation time is only 51 minutes.




evaluation

Evaluation method of cross-border e-commerce supply chain innovation mode based on blockchain technology

In view of the low evaluation accuracy of the effectiveness of cross-border e-commerce supply chain innovation model and the low correlation coefficient of innovation model influencing factors, the evaluation method of cross-border e-commerce supply chain innovation model based on blockchain technology is studied. First, analyse the operation mode of cross-border e-commerce supply chain, and determine the key factors affecting the innovation mode; Then, the comprehensive integration weighting method is used to analyse the factors affecting innovation and calculate the weight value; Finally, the blockchain technology is introduced to build an evaluation model for the supply chain innovation model and realise the evaluation of the cross-border e-commerce supply chain innovation model. The experimental results show that the evaluation accuracy of the proposed method is high, and the highest correlation coefficient of the influencing factors of innovation mode is about 0.99, which is feasible.




evaluation

An evaluation of customer trust in e-commerce market based on entropy weight analytic hierarchy process

In order to solve the problems of large generalisation error, low recall rate and low retrieval accuracy of customer evaluation information in traditional trust evaluation methods, an evaluation method of customer trust in e-commerce market based on entropy weight analytic hierarchy process was designed. Firstly, build an evaluation index system of customer trust in e-commerce market. Secondly, the customer trust matrix is established, and the index weight is calculated by using the analytic hierarchy process and entropy weight method. Finally, five-scale Likert method is used to analyse the indicator factors and establish a comment set, and the trust evaluation value is obtained by combining the indicator membership. The experiment shows that the maximum generalisation error of this method is only 0.029, the recall rate is 97.5%, and the retrieval accuracy of customer evaluation information is closer to 1.




evaluation

The Evaluation of a Computer Ethics Program




evaluation

Evaluation of Web Pages as a Tool in Public Relations




evaluation

Teaching and Learning with BlueJ: an Evaluation of a Pedagogical Tool




evaluation

CAB - Collaboration across Borders: Peer Evaluation for Collaborative Learning




evaluation

End-to-End Performance Evaluation of Selected TCP Variants across a Hybrid Wireless Network 




evaluation

Processes for Ex-ante Evaluation of IT Projects - Case Studies in Brazilian Companies




evaluation

The Development, Use and Evaluation of a Program Design Tool in the Learning and Teaching of Software Development




evaluation

Interactive On-line Formative Evaluation of Student Assignments




evaluation

Warranty and the Risk of Misinforming: Evaluation of the Degree of Acceptance




evaluation

Evaluation of a Suite of Metrics for Component Based Software Engineering (CBSE)




evaluation

Evaluation of Web Based Information Systems: Users’ Informing Criteria




evaluation

The Adoption of Single Sign-On and Multifactor Authentication in Organisations: A Critical Evaluation Using TOE Framework




evaluation

A Collaborative Writing Approach to Wikis: Design, Implementation, and Evaluation




evaluation

Evaluation of a Team Project Based Learning Module for Developing Employability Skills




evaluation

Combining Summative and Formative Evaluation Using Automated Assessment

Aim/Purpose: Providing both formative and summative assessment that allows students to learn from their mistakes is difficult in large classes. This paper describes an automated assessment system suitable for courses with even 100 or more students. Background: Assessment is a vital part of any course of study. Ideally students should be given formative assessment with feedback during the course so students and tutors can identify weaknesses and focus on what needs improvement before summative assessment, which results in a grade. This paper describes and automated assessment system that lessens the burden of providing formative assessment in large classes. Methodology: We used Checkpoint, a web-based automated assessment system, to grade assignments in a number of different computer science courses. Contribution: The students come from diverse backgrounds, with a wide range of ages, previous qualifications and technical skills, and our approach allows the students to work at their own pace according to their individual needs, submitting their solutions as many times as they wish up to a deadline, using feedback provided by the system to help identify and correct their mistakes before trying again. Findings: Use of automated assessment allows us to achieve the goals of both summative and formative assessment: we allow students to learn from their mistakes without incurring a penalty, while at the same time awarding them a grade to validate their efforts. The students have an overwhelmingly positive view about our use of automated assessment, and their comments support our views on the assessment process. Recommendations for Practitioners: Because of the increasing number of students in today’s courses, we recommend using automated assessment wherever possible.




evaluation

Criteria for the Evaluation of Business Process Simulation Tools




evaluation

Estimating the Accuracy of the Return on Investment (ROI) Performance Evaluations

Return on Investment (ROI) is one of the most popular performance measurement and evaluation metrics. ROI analysis (when applied correctly) is a powerful tool in comparing solutions and making informed decisions on the acquisitions of information systems. The purpose of this study is to provide a systematic research of the accuracy of the ROI evaluations in the context of information systems implementations. Measurements theory and error analysis, specifically propagation of uncertainties methods, were used to derive analytical expressions for ROI errors. Monte Carlo simulation methodology was used to design and deliver a quantitative experiment to model costs and returns estimating errors and calculate ROI accuracies. Spreadsheet simulation (Microsoft Excel spreadsheets enhanced with Visual Basic for Applications) was used to implement Monte Carlo simulations. The main contribution of the study is that this is the first systematic effort to evaluate ROI accuracy. Analytical expressions have been derived for estimating errors of the ROI evaluations. Results of the Monte Carlo simulation will help practitioners in making informed decisions based on explicitly stated factors influencing the ROI uncertainties.




evaluation

A Study of the Design and Evaluation of a Learning Object and Implications for Content Development




evaluation

Evaluation of Learning Objects from the User's Perspective: The Case of the EURIDICE Service




evaluation

Using the Interactive White Board in Teaching and Learning – An Evaluation of the SMART CLASSROOM Pilot Project




evaluation

Assessing Online Learning Objects: Student Evaluation of a Guide on the Side Interactive Learning Tutorial Designed by SRJC Libraries




evaluation

Developing a Conceptual Framework for Evaluation of E-Content of Virtual Courses: E-Learning Center of an Iranian University Case Study




evaluation

Internal Data Market Services: An Ontology-Based Architecture and Its Evaluation




evaluation

Evaluation of the Human Impact of Password Authentication