The Discoidin, CUB, and LCCL domain-containing protein (DCBLD) family consists of two type-I transmembrane scaffolding receptors, DCBLD1 and DCBLD2, which play important roles in development and cancer. The nonreceptor tyrosine kinases FYN and ABL are known to drive phosphorylation of tyrosine residues in YXXP motifs within the intracellular domains of DCBLD family members, which leads to the recruitment of the Src homology 2 (SH2) domain of the adaptors CT10 regulator of kinase (CRK) and CRK-like (CRKL). We previously characterized the FYN- and ABL-driven phosphorylation of DCBLD family YXXP motifs. However, we have identified additional FYN- and ABL-dependent phosphorylation sites on DCBLD1 and DCBLD2. This suggests that beyond CRK and CRKL, additional DCBLD interactors may be regulated by FYN and ABL activity. Here, we report a quantitative proteomics approach in which we map the FYN- and ABL-regulated interactomes of DCBLD family members. We found FYN and ABL regulated the binding of several signaling molecules to DCBLD1 and DCBLD2, including members of the 14-3-3 family of adaptors. Biochemical investigation of the DCBLD2/14-3-3 interaction revealed ABL-induced binding of 14-3-3 family members directly to DCBLD2.

AN3453 - Sensored 3-Phase BLDC Motor Control Using Sinusoidal Drive

Voter's names missing from lists is not unusual any more. But, in Bhendi Bazaar, an entire building full of voters has vanished from the list, leaving around 100 residents without their right to vote in this election.

Salam Khan, a 32-year-old businessman, has been casting his vote for years. On Monday, however, he got the shock of his life when he was informed that his name was missing from the voters' list. When he returned home, miffed, he discovered that all the residents of his building, Zainabiya, were not on the list for some reason.

"When I reached the polling booth, I was told that my name was not on it. I was very upset. Then when I reached home, my neighbours, too, start complaining about the same thing. Later, we got to know that the name of the building had gone missing from the list. This is such a big mistake, they have lost so many voters," said Khan.

Also Read: Election 2019: Mumbai scrapes through in voting report card

The residents alleged that they heard that because the building was old, the election officer was told that the structure had been demolished for redevelopment. "We cast our last vote during the BMC election in 2017. There was no problem then. But now, the whole building has gone missing. How is it possible?" asked Rasheed Sheikh.

Election 2019: Prominent personalities, other Mumbaikars come out to caste vote!

Crèches at polling booths

The Election Commission roped in Aanganwadi Sevikas on voting day to take care of children coming with their parents to voting centres. While several such Sevikas were seen standing near the polling stations to take care of children so that they don't enter polling booths, other arrangements were made in rooms inside various schools where parents could leave their kids for a short while to vote.

Also Read: Elections 2019: Regular voters find their name missing at polling booths

In Prabhadevi, 147 Aanganwadi workers were roped in for this. A municipal school at Prabhadevi saw about 40 children taken care by these workers throughout the day. Even at Malad, the crèche was a big hit. Vandana Kothekar, who was on election duty and taking care of these kids from Prabhadevi, said, "We saw a good turnout and parents were willing to keep their children as it was just a matter of a few minutes."

Salman Khan, SRK, Ranveer Singh, Kangana, Bachchans step out for voting

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Imports - Machines & Devices To The Equip. Of Bldg. in Switzerland increased to 195.08 CHF Million in March from 183.92 CHF Million in February of 2020. Imports - Machines & Devices To The Equip. Of Bldg in Switzerland averaged 185.61 CHF Million from 2014 until 2020, reaching an all time high of 234.78 CHF Million in July of 2019 and a record low of 138.88 CHF Million in January of 2015. This page includes a chart with historical data for Switzerland Imports of Machines & Devices to The Equip. of Bl.

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