axon Dinoflagellate cyst taxonomy of the Late Cretaceous Smoking Hills Formation (Horton-Anderson Plains, NWT) By geoscan.nrcan.gc.ca Published On :: Tue, 01 Sep 2020 00:00:00 EDT Bringué, M; Fensome, R A; Galloway, J M. Geoconvention 2020 abstracts; 2020 p. 1-2<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20190494.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20190494.jpg" title="Geoconvention 2020 abstracts; 2020 p. 1-2" height="150" border="1" /></a> Full Article
axon Algorithms for the Evaluation of Ontologies for Extended Error Taxonomy and their Application on Large Ontologies By www.jucs.org Published On :: 2011-07-20T10:20:31+02:00 Ontology evaluation is an integral and important part of the ontology development process. Errors in ontologies could be catastrophic for the information system based on those ontologies. As per our experiments, the existing ontology evaluation systems were unable to detect many errors (like, circulatory error in class and property hierarchy, common class and property in disjoint decomposition, redundancy of sub class and sub property, redundancy of disjoint relation and disjoint knowledge omission) as defined in the error taxonomy. We have formulated efficient algorithms for the evaluation of these and other errors as per the extended error taxonomy. These algorithms are implemented (named as OntEval) and the implementations are used to evaluate well-known ontologies including Gene Ontology (GO), WordNet Ontology and OntoSem. The ontologies are indexed using a variant of already proposed scheme Ontrel. A number of errors and warnings in these ontologies have been discovered using the OntEval. We have also reported the performance of our implementation, OntEval. Full Article
axon A Return on Investment as a Metric for Evaluating Information Systems: Taxonomy and Application By Published On :: Full Article
axon PRATO: An Automated Taxonomy-Based Reviewer-Proposal Assignment System By Published On :: 2018-10-20 Aim/Purpose: This paper reports our implementation of a prototype system, namely PRATO (Proposals Reviewers Automated Taxonomy-based Organization), for automatic assignment of proposals to reviewers based on categorized tracks and partial matching of reviewers’ profiles of research interests against proposal keywords. Background: The process of assigning reviewers to proposals tends to be a complicated task as it involves inspecting the matching between a given proposal and a reviewer based on different criteria. The situation becomes worse if one tries to automate this process, especially if a reviewer partially matches the domain of the paper at hand. Hence, a new controlled approach is required to facilitate the matching process. Methodology: Proposals and reviewers are organized into categorized tracks as defined by a tree of hierarchical research domains which correspond to the university’s colleges and departments. In addition, reviewers create their profiles of research interests (keywords) at the time of registration. Initial assignment is based on the matching of categorized sub-tracks of proposal and reviewer. Where the proposal and a reviewer fall under different categories (sub-tracks), assignment is done based on partial matching of proposal content against re-viewers’ research interests. Jaccard similarity coefficient scores are calculated of proposal keywords and reviewers’ profiles of research interest, and the reviewer with highest score is chosen. The system was used to automate the process of proposal-reviewer assignment at the Umm Al-Qura University during the 2017-2018 funding cycle. The list of proposal-reviewer assignments generated by the system was sent to human experts for voting and subsequently to make final assignments accordingly. With expert votes and final decisions as evaluation criteria, data system-expert agreements (in terms of “accept” or “reject”) were collected and analyzed by tallying frequencies and calculating rejection/acceptance ratios to assess the system’s performance. Contribution: This work helped the Deanship of Scientific Research (DSR), a funding agency at Umm Al-Qura University, in managing the process of reviewing proposals submitted for funding. We believe the work can also benefit any organizations or conferences to automate the assignment of papers to the most appropriate reviewers. Findings: Our developed prototype, PRATO, showed a considerable impact on the entire process of reviewing proposals at DSR. It automated the assignment of proposals to reviewers and resulted in 56.7% correct assignments overall. This indicates that PRATO performed considerably well at this early stage of its development. Recommendations for Practitioners: It is important for funding agencies and publishers to automate reviewing process to obtain better reviewing quality in a timely manner. Recommendation for Researchers: This work highlighted a new methodology to tackle the proposal-reviewer assignment task in an automated manner. More evaluation might be needed with consideration of different categories, especially for partially matched candidates. Impact on Society: The new methodology and knowledge about factors influencing the implementation of automated proposal-reviewing systems will help funding agencies and publishers to improve the quality of their internal processes. Future Research: In the future, we plan to examine PRATO’s performance on different classification schemes where specialty areas can be represented in graphs rather than trees. With graph representation, the scope for reviewer selection can be widened to include more general fields of specialty. Moreover, we will try to record the reasons for rejection to identify accurately whether the rejection was due to improper assignment or other reasons. Full Article
axon Taxonomy of Students’ Use of The iPad in Education: A Pilot By Published On :: 2015-06-11 This study attempts to present the variety of possible uses for iPads, in the learning process. The objective is to evaluate a unique implementation model that was tried out at a teacher training college in Israel. The methodology is based on a qualitative research paradigm. The findings show that students’ use the iPads in various contexts: (a) for ongoing personal use; (b) for planning lessons; (c) for active integration in the classroom; and (d) for reading and developing content and games. These findings are summarized in a chart that shows the different uses as levels in a hierarchical taxonomy. Analysis of the iPad’s pedagogical uses may shed light on the various skills students need to acquire in order to become teachers in 21st century. In addition, understanding the various iPad uses and their frequency can affect decision-making at the level of policy in the field of implementation of the use of mobile technologies in educational institutions. Full Article
axon An I-Based Taxonomy of Virtual Organisations and the Implications for Effective Management By Published On :: Full Article
axon FishBase and Fish Taxonomy Training Course 2014: Call for Traineeship By www.eubon.eu Published On :: Fri, 11 Oct 2013 10:39:59 +0300 The Royal Museum for Central Africa (RMCA) in Tervuren (Belgium) is part of the FishBase Consortium and responsible for the information on the fresh- and brackish water fishes of Africa. Through an agreement with the Belgian Development Cooperation and as part of the FishBase programme, the RMCA has five grants available for a 3-month training programme in the use of FishBase and the taxonomy of African fishes. The training includes three subsets: A detailed explanation of FishBase in all its aspects; A training in the taxonomy of African fishes; and A case study based on data from FishBase or on taxa for which taxonomic problems have been encountered. The main focus of the training is on fish biodiversity data and their integration into FishBase, and on how to use and contribute data to FishBase. The context of these contributions may vary and can also include the knowledge on common names, fish ecology, fisheries statistics, aquaculture and many other areas of fish biology. After the training, the participants should be able to make their own contribution to fish biology and continue to work on FishBase. They are encouraged to teach their newly apprehended skills to new/local users, to help in completing the database and keeping it up to date, and to spread the use of FishBase as a source of information and a fisheries tool. This course has been offered annually since 2005 and is held at the Royal Museum for Central Africa (Leuvensesteenweg 13, B-3080 Tervuren, Belgium). To apply for traineeship and for more information, go to:http://www.africamuseum.be/research/collaborations/training/group?set_language=en&cl=en Please note that for 2014, this course will be given in French only. Contact: Dimitri Geelhand de Merxem (dimitri.geelhand@africamuseum.be) Full Article News
axon Next-generation global e-infrastructure for taxon names registry By www.eubon.eu Published On :: Mon, 04 Nov 2013 17:55:00 +0200 Zookeys, the first zoological journal to introduce automatic registration in ZooBank The latest issue of ZooKeys - no. 346 - has been automatically registered in ZooBank on its day of publication last Friday. This marks the successful deployment of an automated registration-to-publication pipeline for taxonomic names for animals. The innovative workflow was jointly funded by the EU FP7 funded project pro-iBiosphere and a U.S. National Science Foundation project to develop the Global Names Architecture (DBI-1062441). The process of post-publication recording and indexing of species names has a long tradition, in some cases dating as far back as the middle of 19th century. But now in the 21st century with the advance of modern technologies and the opportunity to publish taxonomic novelties online, the process of post-publication recording brought into focus the concept of automated pre-publication registration. Why is this important? The proportion of 'turbo-taxonomic' papers describing hundreds of new species increases. Registration of hundreds of new species is an issue, however it is even more important that the final publication data of the pre-registered names are reported back to ZooBank on the day of publication. Launched as an open access peer reviewed journal in 2008, to coincide and adopt from inception the International Code of Zoological Nomenclature changes for electronic publications, ZooKeys was the first journal to provide a mandatory in-house registration in ZooBank. Since 2008, it has contributed about one third of all names currently registered in ZooBank. With the adoption of the automated ZooBank registration, ZooKeys continues its mission to set novel trends in biodiversity publishing. Implementation of automated workflows and invention of XML-based tools will facilitate the process of publication and dissemination of biodiversity information. It will pave the way for unification and streamlining the registration process, even more to building the next-generation e-infrastructure for a common global taxon names registry. Within the pro-iBiosphere project and in cooperation with Plazi that have created the TaxPub XML schema, an automated registration workflow for plants has already been established between the International Plant Names Index (IPNI) and the PhytoKeys journal, to be applied soon also for fungi between Index Fungorum and the journal MycoKeys. Full Article News
axon Memorandum of understanding signed between EU BON and CETAF (Consortium of European Taxonomic Facilities) By www.eubon.eu Published On :: Wed, 04 Jun 2014 14:49:00 +0300 A memorandum of understanding has been signed between EU BON and CETAF (Consortium of European Taxonomic Facilities, AISBL). The document was signed by EU BON project coordinator Christoph Häuser and the Chair of CETAF, Dr. Michelle J. Price, during the 35th CETAF General Meeting in Oslo, 6-7 May, 2014. CETAF is a networked consortium of scientific institutions in Europe formed to promote training, research and understanding of systematic biology and palaeobiology, Together, CETAF institutions hold very substantial biological (zoological and botanical), palaeobiological, and geological collections and provide the resources necessary for the work of thousands of researchers in a variety of scientific disciplines. Meanwhile the list of MoU signed by EU BON has grown with further institutions/projects joining: http://www.eubon.eu/showpage.php?storyid=10373 Full Article News
axon Distributed European School of Taxonomy (DEST) approaching training courses By www.eubon.eu Published On :: Thu, 19 Jun 2014 13:28:00 +0300 The Distributed European School of Taxonomy (DEST) has been established by prominent taxonomists and other international partners during the EU funded project European Distributed Institute of Taxonomy (EDIT). The major aim of DEST is to transfer knowledge between current and future generations of taxonomists by providing high quality education and prepare students for future taxonomic careers. Overall, DEST involves a network of around 100 training providers from 60 institutions. Within the framework of the EDIT project, DEST organised training sessions in 30 European institutions for 185 students from all over the world (116 of which EDIT-granted). Since March 2011, the Royal Belgian Institute of Natural Sciences remains responsible for the continued management of DEST, organization of courses and related logistical matters. During the academic year 2011-2012, DEST provided training to 100 students through 16 courses, while 130 students participated in 19 training courses during 2012-2013. DEST continues to provide high-quality training to future taxonomists. Below are the deadline for registration for several approaching courses in Modern Taxonomy:Philosophy of Biological Systematics (8-12 September 2014)Course venue: Royal Belgian Institute of Natural Sciences, Brussels, BelgiumTraining provider: Dr. Kirk Fitzhugh, Natural History Museum of Los Angeles County, U.S.A.Registration deadline is being extended untilFriday 20 June 2014 Zoological Nomenclature training course (22-26 September 2014)Course venue: Muséum national d'Histoire naturelle, Paris, FrancTraining provider: Prof. Alain Dubois, Muséum national d'Histoire naturelle, ParisRegistration deadline is being extended untilFriday 20 June 2014Botanical Nomenclature training course (26-30 January 2015)Course venue: Royal Botanic Gardens Kew, U.K.Training provider: Katherine Challis, Royal Botanic Gardens, KewRegistration deadline: 10 October 2014 To read more about the courses and to register, visit the official DEST webpage: http://www.taxonomytraining.eu/content/modern-taxonomy-course-programme-2013-2014 Full Article News
axon European Journal of Taxonomy #100 By www.eubon.eu Published On :: Tue, 28 Oct 2014 12:04:11 +0200 The European Journal of Taxonomy is a peer-reviewed international journal in descriptive taxonomy, covering the eukaryotic world. The content range from descriptions of new species to large inventories of different groups - so far more than 400 new species are described in EJT. Its content is fully electronic and Open Access. It is published and funded by a consortium of European natural history institutions. Neither authors nor readers have to pay fees.The 100th issue of EJT, which was published 24 October 2014, comprises a beautifully illustrated monograph on African millipedes, adding 20 new species to our list of new taxa. Author is Professor Henrik Enghoff from The Natural History Museum of Denmark, University of Copenhagen.No 100 (2014): A mountain of millipedes I: An endemic species-group of the genus Chaleponcus Attems, 1914, from the Udzungwa Mountains, Tanzania (Diplopoda, Spirostreptida, Odontopygidae). Henrik EnghoffEJT normally is an e-only journal, but on this occasion the editorial team has decided to print a limited number of hard copies, to be distributed amongst the Natural History Institutions around the world. Professor Henrik Enghoff represents EU BON partner UCPH. Full Article News
axon FishBase and Fish Taxonomy Training Session 2015 By www.eubon.eu Published On :: Tue, 18 Nov 2014 07:30:56 +0200 The Royal Museum for Central Africa (RMCA) in Tervuren (Belgium) is part of the FishBase Consortium and responsible for the information on the fresh- and brackish water fishes of Africa. Through an agreement with the Belgian Development Cooperation and as part of the FishBase program, the RMCA has five grants available for a 3-month training program in the use of FishBase and the taxonomy of African fishes. The training includes three subsets: A detailed explanation of FishBase in all its aspects; A training in the taxonomy of African fishes; A case study based on data from FishBase or on taxa for which taxonomic problems have been encountered. This course has been offered annually since 2005 and is held at the Royal Museum for Central Africa (Leuvensesteenweg 13, B-3080 Tervuren, Belgium). To apply for traineeship and for more information, please click HERE or HERE. Please note that for 2015, this course will be given in English only. Questions? Contact Dimitri Geelhand de Merxem (dimitri.geelhand@africamuseum.be). Full Article News
axon New life for old data: Integrating and visualizing primary biodiversity data from prospective and legacy taxonomic literature By www.eubon.eu Published On :: Mon, 18 May 2015 15:38:00 +0300 XML markup of taxonomic research and specimen data is a valuable tool for structuring the incessantly accumulating biodiversity knowledge. It allows for the opportunity to collectively use the currently fragmented information for more detailed analysis. A new research paper, published in theBiodiversity Data Journal, demonstrates how XML markup using GoldenGATE can address the challenges presented by unstructured legacy data, like those presented in the widely used PDF format. The paper demonstrates how structured primary biodiversity data can be extracted from such legacy sources and aggregated with and jointly queried with data from other Darwin Core-compatible sources, to present a visualization of these data that can communicate key information contained in biodiversity literature. Specimen data in taxonomic literature are among the highest quality primary biodiversity data. Innovative cybertaxonomic journals such as the Biodiversity Data Journal are using workflows that preserve the data's structure and semantic specificity and disseminate electronic content to aggregators and other users that makes these data reusable. Such structure however is lost in traditional taxonomic publishing and currently, access to that resource is cumbersome, especially for non-specialist data consumers. The question is: how do you manage this vast distributed repository of knowledge about biodiversity to make it easily available reusable for future research? To answer this challenge this project queried XML structured articles published in Biodiversity Data Journal along with historical taxonomic literature marked up using GoldenGATE, and represents the results as a series of standard charts. XML structured documents are maintained by the Swiss NGO Plazi and are freely available online. In such form, data associated with specimens becomes much more valuable as it can reveal key information about a particular species, and even about the scientists who investigate them. Charts indicate at a glance, for example, what time of year and elevation range a species is likely to be found at, useful information if you want to search for it in the field. Our accumulated biodiversity knowledge includes an estimated 2-3 billion specimens in natural history collections and 500 million pages of printed text. These are the data we need to answer questions that are relevant to our world today, like setting conservation priorities and anticipating the effects of climate change on biodiversity and ecosystem functions that affect the lives of people. "In short, we have half a billion pages worth of biodiversity knowledge and are just learning how to query it. The real power comes when data from many articles are combined, queried, and reused for new purposes. Potential applications span the scientific, policy, and public spheres. When we all have better access to the information that already exists in the global corpus of biodiversity literature, this helps us do a better job of exploring what we don't know and wisely applying what we do." explains the lead author Dr Jeremy Miller, Naturalis Biodiversity Center. ### This project was supported by pro-iBiosphere and EU BON, two FP-7 (European Union Seventh Framework Programme, 2007-2013) grants (No 312848 and 308454). Original source: Miller J, Agosti D, Penev L, Sautter G, Georgiev T, Catapano T, Patterson D, King D, Pereira S, Vos R, Sierra S (2015) Integrating and visualizing primary data from prospective and legacy taxonomic literature. Biodiversity Data Journal 3: e5063. doi: 10.3897/BDJ.3.e5063 Full Article News
axon DEST course ‘BASICS of TAXONOMY’ By www.eubon.eu Published On :: Tue, 19 May 2015 10:09:00 +0300 The 4th edition of the DEST course ‘BASICS of TAXONOMY’ will take place from 5 to16 October 2015 at the Sven Lovén Centre for Marine Sciences, Kristineberg, Sweden. Taught by renowned experts in their field, the course topics are: - DELTA- Digital drawing- Scientific illustration- Scientific writing and communication- Scratchpads, a tool to build, publish and share information on the web Target audience: MSc students, PhD students, early career researchers Thanks to funding of the Royal Swedish Academy of Sciences, this 2-weeks course is offered at a discounted rate of 550 EUR. Fee includes accommodation and meals. More info: http://taxonomytraining.eu/content/basics-taxonomy-describing-illustrating-and-communicating-biodiversity Full Article News
axon Pan-European Species-directories Infrastructure: Basis for handling big taxonomic data By www.eubon.eu Published On :: Wed, 30 Sep 2015 18:39:00 +0300 Looked down on with scepticism by many taxonomists, handling big data efficiently is a huge challenge that can only be met with thorough and multi-layered efforts from both scientists and technological developers. Projects like the Pan-European Species-directories Infrastructure (PESI), started in 2009, prove that harmonised taxonomic reference systems and high-quality data sets are possible through dynamic, expertly created and managed online tools. The methods, results and future prospects of PESI are available in the open access Biodiversity Data Journal. With environmental changes occurring at an unprecedented rate around the world, biological communication needs to be left off the pace at no point. Phenomena such as species' migration, extinction, intrusion; ecosystem stability; decline of pollinators and pest invasion have to be monitored closely and identified momentarily. In order to do so, proper identification based on reliable and easily accessible data is crucial. Therefore, the three key objectives of PESI include standardisation in taxonomic reference systems, enhancement of the quality and completeness of taxonomic data sets and creation of integrated access to taxonomic information. The five pillars of biological community networks, Zoology, Botany, Marine Biota, Mycology and Phycology, have been integrated in five infrastructural components: knowledge, consensus, standards, data and dissemination. As a result, PESI did not only merge data from a range of sources and published a total of nearly 450,000 scientific names online. It also maintains networks of outstanding experts and national focal points, so that it makes sure that the taxonomic information, it relies on, is always at its finest, while simultaneously takes care about delivering persistent standards and easily accessible up-to-date biodiversity data. PESI results will also feed as an essential part for the advancement of relevant EU projects, such as Building the European Biodiversity Observation Network (EU BON). In the EU BON project, the PESI Backbone will be advanced to satisfy the needs of the GEO BON / GEOSS system, also serving as a taxonomic backbone for the projected EU BON Biodiversity Portal. Aiming at standardisation and integration of taxonomic data across platforms PESI also works in close collaboration with other relevant projects including GBIF, LifeWatch, the Catalogue of Life, the Encyclopedia of Life, the Global Names Architecture, GÉANT, ViBRANT, OpenUp!,BioVeL, iMarine , EU BON and BiodiversityKnowledge . "Scientific names are key carriers of biodiversity information. Therefore, for the efficient exploring and integration of biodiversity data, the development of a functional taxonomic resolution system, including the establishment of a shared taxonomic standard (as a core component), is essential for all sorts of biodiversity assessments. PESI provides such an infrastructure for Europe, integrating the relevant technical (informatics) and social (knowledge & users) networks into a common work program, serving a wide community of biodiversity workers," says Dr. Yde de Jong, coordinator of the Pan-European Species-directories Infrastructure (PESI) project. "The PESI Taxonomic Backbone serves as a taxonomic data standard resource, facilitating and optimising the integration and sharing of European biodiversity data, supporting a wide range of European services, major biodiversity programs and stakeholders on nature conservation and biodiversity management," conclude their results the scientists. Original Source: de Jong Y, et al. (2015) PESI - a taxonomic backbone for Europe. Biodiversity Data Journal 3: e5848.doi: 10.3897/BDJ.3.e5848 Additional Information: The Pan-European Species-directories Infrastructure (PESI) provides standardised and authoritative taxonomic information by integrating and securing Europe's taxonomically authoritative species name registers and nomenclators (name databases) and associated expert(ise) networks that underpin the management of biodiversity in Europe. PESI kicked-off as an EC-FP7 project, running from 2009 to 2011. PESI proceeded from the EC-FP6 Networks of Excellence EDIT, on developing a European Distributed Institute of Taxonomy, and MarBEF, on Marine Biodiversity and Ecosystem Functioning. Building the European Biodiversity Observation Network (EU BON) is a European research project, financed by the 7th EU framework programme for research and development (FP7). EU BON seeks ways to better integrate biodiversity information and implement into policy and decision-making of biodiversity monitoring and management in the EU. Full Article News
axon Call for Applications (Traineeship): FishBase and Fish Taxonomy Training Session 2016 By www.eubon.eu Published On :: Mon, 26 Oct 2015 12:50:53 +0200 The Royal Museum for Central Africa (RMCA) in Tervuren (Belgium) is part of the FishBase Consortium and responsible for the information on the fresh- and brackish water fishes of Africa in the FishBase database. Through an agreement with the Belgian Development Cooperation and as part of the FishBase program, the RMCA has five (5) grants available for a 3-month training program in the use of FishBase and the taxonomy of African fishes. The training will have three subsets: A detailed explanation of FishBase in all its aspects; A training in the taxonomy of African fishes; A case study based on data from FishBase or on taxa for which taxonomic problems have been encountered. This course has been offered annually since 2005 and is held at the Royal Museum for Central Africa (Leuvensesteenweg 13, B-3080 Tervuren, Belgium). For more information and to apply for this three-month training grant, see: http://fishbase.africamuseum.be or www.fishbaseforafrica.org. Please note that for 2016, this course will be given in French only. Questions? Contact Dimitri Geelhand de Merxem (dimitri.geelhand@africamuseum.be). Full Article News
axon Streamlined import of specimen & occurrence records into taxonomic manuscripts By www.eubon.eu Published On :: Fri, 30 Oct 2015 10:55:00 +0200 Substantial amount of documented occurrence records is awaiting publication stored in repositories and data indexing platforms, such as the Global Biodiversity Information Facility (GBIF), Barcode of Life Data Systems (BOLD Systems), or Integrated Digitized Biocollections (iDigBio). In order to streamline the authoring process, save taxonomists time, and provide a workflow for peer-review and quality checks, Pensoft has introduced an innovative feature that makes it possible to easily import occurrence records into a taxonomic manuscript. Prior to this development, Pensoft's ARPHA Writing Tool (AWT) only used the "upload from Excel" approach for this workflow. Although this method significantly simplified the process of importing materials and is actively used by the authors, it still required one extra transposition step. Now, we added a new even more user-friendly option. By simply specifying an identifier (ID) in the relevant box, the new import plugin allows for occurrence data, stored at GBIF, BOLD systems, or iDigBio, to be be directly inserted into the manuscript. It all happens in the user-friendly environment of the AWT, where the imported data can be then edited before submission to the Biodiversity Data Journal. Not having to retype or copy/paste species occurrence records, the authors save a lot of efforts. Moreover, they automatically import them in a structured Darwin Core format, which can be easily downloaded from the article text into structured data by anyone who needs the data for reuse after publication. Another important aspect of the workflow is that it will serve as a platform for peer-review, publication and curation of raw data, that is of unpublished individual data records coming from collections or observations stored at GBIF, BOLD and iDigBio. The work has been partially supported by the EC-FP7 EU BON project (ENV 308454, Building the European Biodiversity Observation Network) and the ITN Horizon 2020 project BIG4(Biosystematics, informatics and genomics of the big 4 insect groups: training tomorrow's researchers and entrepreneurs), under Marie Sklodovska-Curie grant agreement No. 542241. Full Article News
axon The DEST taxonomy training programme 2015-2016 By www.eubon.eu Published On :: Mon, 23 Nov 2015 09:44:00 +0200 The Distributed European School of Taxonomy (DEST), an initiative under the CETAF umbrella and managed by RBINS, has launched its training programme for 2015-2016. Check out the Expert-in-training programme enabling trainees to develop and strengthen their taxonomic research skills through on-the-job-training and the Modern Taxonomy programme offering intensive theoretical courses in various subjects. The Distributed European School of Taxonomy (DEST) was established within the framework of the EU funded project European Distributed Institute of Taxonomy (EDIT) and under the umbrella of the Consortium of European Taxonomic Facilities (CETAF). The EDIT consortium agreement lasted from March 2006 until March 2011. Since then, the Royal Belgian Institute of Natural Sciences (RBINS) remains responsible for the continued management of DEST, organization of courses and related logistical matters. The DEST currently includes a network of around 100 training providers from 60 institutions. Full Article News
axon Article Alert: How Aphia Can Serve Both the Taxonomic Community and the Field of Biodiversity Informatics By www.eubon.eu Published On :: Tue, 22 Dec 2015 18:26:00 +0200 A new article published in the Journal of Marine Science and Engineering looks at how Aphia, the core platform that underpins the World Register of Marine Species (WoRMS), can Serve the taxonomic community and the field of biodiversity informatics. Abstract The Aphia platform is an infrastructure designed to capture taxonomic and related data and information, and includes an online editing environment. The latter allows easy access to experts so they can update the content of the database in a timely fashion. Aphia is the core platform that underpins the World Register of Marine Species (WoRMS) and its more than 80 related global, regional and thematic species databases, but it also allows the storage of non-marine data. The content of Aphia can be consulted online, either by individual users or via machine-to-machine interactions. Aphia uses unique and stable identifiers for each available name in the database through the use of Life Science Identifiers (LSIDs). The system not only allows the storage of accepted and unaccepted names, but it also documents the relationships between names. This makes it a very powerful tool for taxonomic quality control, and also allows the linking of different pieces of information through scientific names, both within the Aphia platform and in relation to externally hosted databases. Through these LSIDs, Aphia has become an important player in the field of (marine) biodiversity informatics, allowing interactions between its own taxonomic data and e.g., biogeographic databases. Some applications in the field of biodiversity informatics encompass the coupling of species traits and taxonomy, as well as the creation of diverse, expert validated data products that can be used by policy makers, for example. Aphia also supplies (part of) its content to other data integrators and the infrastructure can be used to host orphan databases in danger of being lost. Original Source: http://www.mdpi.com/2077-1312/3/4/1448/htm Full Article News
axon Article Alert: Linking Earth Observation and taxonomic, structural and functional biodiversity: Local to ecosystem perspectives By www.eubon.eu Published On :: Fri, 01 Jul 2016 18:23:00 +0300 A new research paper Linking Earth Observation and taxonomic, structural and functional biodiversity: Local to ecosystem perspectives published in the journal Ecological Indicators looks at the ways in which earth observation (EO) techniques may provide a solution to overcome shortcomings in biodiversity monitoring by measuring entities of interest at different spatial and temporal scales. Abstract: Impacts of human civilization on ecosystems threaten global biodiversity. In a changing environment, traditional in situ approaches to biodiversity monitoring have made significant steps forward to quantify and evaluate BD at many scales but still, these methods are limited to comparatively small areas. Earth observation (EO) techniques may provide a solution to overcome this shortcoming by measuring entities of interest at different spatial and temporal scales. This paper provides a comprehensive overview of the role of EO to detect, describe, explain, predict and assess biodiversity. Here, we focus on three main aspects related to biodiversity taxonomic diversity, functional diversity and structural diversity, which integrate different levels of organization molecular, genetic, individual, species, populations, communities, biomes, ecosystems and landscapes. In particular, we discuss the recording of taxonomic elements of biodiversity through the identification of animal and plant species. We highlight the importance of the spectral traits (ST) and spectral trait variations (STV) concept for EO-based biodiversity research. Furthermore we provide examples of spectral traits/spectral trait variations used in EO applications for quantifying taxonomic diversity, functional diversity andstructural diversity. We discuss the use of EO to monitor biodiversity and habitat quality using differ-ent remote-sensing techniques. Finally, we suggest specifically important steps for a better integrationof EO in biodiversity research.EO methods represent an affordable, repeatable and comparable method for measuring, describing,explaining and modelling taxonomic, functional and structural diversity. Upcoming sensor developmentswill provide opportunities to quantify spectral traits, currently not detectable with EO, and will surelyhelp to describe biodiversity in more detail. Therefore, new concepts are needed to tightly integrate EOsensor networks with the identification of biodiversity. This will mean taking completely new directionsin the future to link complex, large data, different approaches and models. Original reseach: A. Lausch, L. Bannehr, M. Beckmann, C. Boehm, H. Feilhauer, J.M. Hacker, M. Heurich, A. Jung, R. Klenke, C. Neumann, M. Pause, D. Rocchini, M.E. Schaepman, S. Schmidtlein, K. Schulz, P. Selsam, J. Settele, A.K. Skidmore, A.F. Cord, Linking Earth Observation and taxonomic, structural and functional biodiversity: Local to ecosystem perspectives, Ecological Indicators, Volume 70, November 2016, Pages 317-339, ISSN 1470-160X, http://dx.doi.org/10.1016/j.ecolind.2016.06.022 Full Article News
axon FishBase and Fish Taxonomy Training Course 2014 By www.eubon.eu Published On :: Fri, 11 Oct 2013 10:23:38 +0300 The Royal Museum for Central Africa (RMCA) in Tervuren (Belgium) is part of the FishBase Consortium and responsible for the information on the fresh- and brackish water fishes of Africa. Through an agreement with the Belgian Development Cooperation and as part of the FishBase programme, the RMCA has five grants available for a 3-month training programme in the use of FishBase and the taxonomy of African fishes. The training includes three subsets: A detailed explanation of FishBase in all its aspects; A training in the taxonomy of African fishes; and A case study based on data from FishBase or on taxa for which taxonomic problems have been encountered. The main focus of the training is on fish biodiversity data and their integration into FishBase, and on how to use and contribute data to FishBase. The context of these contributions may vary and can also include the knowledge on common names, fish ecology, fisheries statistics, aquaculture and many other areas of fish biology. After the training, the participants should be able to make their own contribution to fish biology and continue to work on FishBase. They are encouraged to teach their newly apprehended skills to new/local users, to help in completing the database and keeping it up to date, and to spread the use of FishBase as a source of information and a fisheries tool. This course has been offered annually since 2005 and is held at the Royal Museum for Central Africa (Leuvensesteenweg 13, B-3080 Tervuren, Belgium). To apply for traineeship and for more information, go to:http://www.africamuseum.be/research/collaborations/training/group?set_language=en&cl=en Please note that for 2014, this course will be given in French only. Full Article Events
axon Distributed European School of Taxonomy (DEST) Course: Philosophy of Biological Systematics By www.eubon.eu Published On :: Thu, 19 Jun 2014 13:52:00 +0300 Distributed European School of Taxonomy (DEST) is organizing a course in Philosophy of Biological Systematics targeted at MSc students, PhD students, early career researchers, professional systematists/taxonomists and anyone who is interested in the philosophy of Biological Systematics. The course has a duration of one week and will take place between 8-12 September 2014. Deadline for registration: 16 June 2014, extended until Friday 20 June 2014. To register and to learn more about the course visit the official webpage: http://www.taxonomytraining.eu/content/philosophy-biological-systematics Approaching the subject from the perspective of the philosophical foundations of scientific inquiry, this course offers critical examinations of the principles required to judge the scientific merits of systematic/taxonomic procedures by way of the following topics: • The goal of science• The goal of biological systematics• Causal relationships in systematics• The nature of why-questions• Three forms of reasoning: deduction, induction, abduction• The uses of deduction, induction, and abduction in science• Evidence and reasoning• Fact, theory & hypothesis• Theory & hypothesis testing• Systematics involves abductive reasoning• Inferences of systematics hypotheses, i.e. taxa• Implications for ‘phylogenetic’ methods• Causal explanations, not ‘trees’ or cladograms• Parsimony, likelihood, Bayesianism: are they relevant to abductive reasoning, thus phylogenetic inference?• The requirement of total evidence• The errors of cladogram comparisons & character mapping• Homology, homogeny & homoplasy• Character coding• Mechanics of hypothesis testing: implications for cladograms• Character data cannot test phylogenetic hypotheses• The nature evidential support• The proper testing of phylogenetic hypotheses• The myths of bootstrap, jack-knife & Bremer ‘support’• Implications for nomenclature• Defining biodiversity and conservation Participants will be provided reprints covering the topics in the course, as well as a PDF file with all course slides (>800) and associated notes. Full Article Events
axon Distributed European School of Taxonomy (DEST): Zoological Nomenclature training course By www.eubon.eu Published On :: Thu, 19 Jun 2014 14:00:00 +0300 Distributed European School of Taxonomy (DEST) is organizing a Zoological Nomenclature training course targeted at MSc students, PhD students, early career researchers, professional systematists/taxonomists and anyone who is interested in the philosophy of Biological Systematics. The course has a duration of one 5 days and will take place between 22-26 September 2014 at the Muséum national d'Histoire naturelle, Paris, France. Deadline for registration: 16 June 2014, extended until Friday 20 June 2014. To register and to learn more about the course visit the official webpage: http://www.taxonomytraining.eu/content/zoological-nomenclature-3 Course description: Taxonomists need a common language worldwide. This is provided by the international codes of nomenclature. Although several codes exist, according to the organisms at stake, they all follow a similar mode of allocation of names to taxa (through "types") and of establishment of the valid name for a taxon (priority, first-reviser, usage). As biological nomenclature is rarely taught in academic formations, many taxonomists have difficulties mastering it. This training will provide an overview of the history and epistemology of biological nomenclature, and a discussion of the relationships between phylogeny, taxonomy and nomenclature. The zoological code will be presented in detail, the other codes (including the botanical one) more briefly. The recent problems and projects of nomenclature, including alternative systems, will be discussed. Lecture topics: • What is taxonomy? What is nomenclature? Name, taxon, nomenclatural rank, taxonomic category. Species and supraspecific taxa. The relationships between phylogeny, taxonomy and nomenclature• History and epistemology of the international codes of nomenclature• The international code of zoological nomenclature• The other international codes (plants and fungi, bacteria, viruses, cultivated plants)• The alternative nomenclatural systems Seminar topics: • Nomenclature of higher taxa in zoology• The Phylocode and other phylogenetic nomenclatural systems• Zoobank and electronic publications Practical experiences will include: exercises in zoological nomenclature and transforming phylogenetic data into a taxonomy and a nomenclature. Full Article Events
axon Distributed European School of Taxonomy (DEST): Botanical Nomenclature training course By www.eubon.eu Published On :: Thu, 19 Jun 2014 14:08:00 +0300 Distributed European School of Taxonomy (DEST) is organizing a Botanical Nomenclature training course targeted at MSc students, PhD students, early career researchers, professional systematists/taxonomists and anyone who is interested in the philosophy of Biological Systematics. The course has a duration of one week and will take place between 26-30 January 2015 at the Royal Botanic Gardens, Kew, UK. Deadline for registrationis 10 October 2014. Participants will receive notification by 24 October 2014 whether accepted to the course. To register and to learn more about the course visit the official webpage: http://www.taxonomytraining.eu/content/botanical-nomenclature-3 Course descriptionThis in-depth course will teach the principles of plant nomenclature according to the International Code of Nomenclature for algae, fungi and plants (ICN) so that participants can apply good nomenclatural practice when undertaking taxonomic revisions, compiling checklists etc. This will be achieved by lectures illustrated with examples from the ICN, workshop sessions applying what has been learned to "real life" cases, and by encouraging participants to discuss nomenclatural problems they have encountered. Participants will have time to pursue their own research interests using the collections at Kew, with the emphasis on identifying and solving nomenclatural problems.Short seminars will give participants the opportunity to present nomenclatural problems relevant to their own research. Full Article Events
axon FishBase and Fish Taxonomy Training Session 2015 (Continues until 26 June) By www.eubon.eu Published On :: Tue, 18 Nov 2014 07:12:00 +0200 The Royal Museum for Central Africa (RMCA) in Tervuren (Belgium) is part of the FishBase Consortium and responsible for the information on the fresh- and brackish water fishes of Africa. Through an agreement with the Belgian Development Cooperation and as part of the FishBase program, the RMCA has five grants available for a 3-month training program in the use of FishBase and the taxonomy of African fishes. The training includes three subsets: A detailed explanation of FishBase in all its aspects; A training in the taxonomy of African fishes; A case study based on data from FishBase or on taxa for which taxonomic problems have been encountered. This course has been offered annually since 2005 and is held at the Royal Museum for Central Africa (Leuvensesteenweg 13, B-3080 Tervuren, Belgium). To apply for traineeship and for more information, please click here or here. Please note that for 2015, this course will be given in English only. Questions? Contact Dimitri Geelhand de Merxem (dimitri.geelhand@africamuseum.be). Full Article Events
axon DEST course ‘BASICS of TAXONOMY’ 4th edition By www.eubon.eu Published On :: Tue, 19 May 2015 10:02:00 +0300 The 4th edition of the DEST course ‘BASICS of TAXONOMY’ will take place from 5 to16 October 2015 at the Sven Lovén Centre for Marine Sciences, Kristineberg, Sweden. Taught by renowned experts in their field, the course topics are: - DELTA- Digital drawing- Scientific illustration- Scientific writing and communication- Scratchpads, a tool to build, publish and share information on the web Target audience: MSc students, PhD students, early career researchers Thanks to funding of the Royal Swedish Academy of Sciences, this 2-weeks course is offered at a discounted rate of 550 EUR. Fee includes accommodation and meals. More info: http://taxonomytraining.eu/content/basics-taxonomy-describing-illustrating-and-communicating-biodiversity Full Article Events
axon FishBase and Fish Taxonomy Training Session 2016 By www.eubon.eu Published On :: Mon, 26 Oct 2015 12:54:39 +0200 The Royal Museum for Central Africa (RMCA) in Tervuren (Belgium), member of the FishBase Consortium and responsible for the information on the fresh- and brackish water fishes of Africa in the FishBase database, is organizing the 'FishBase and Fish Taxonomy Training Session 2016'. This course has been offered annually since 2005 and held regularly in the RMCA located at Leuvensesteenweg 13, B-3080 Tervuren, Belgium. Through an agreement with the Belgian Development Cooperation and as part of the FishBase program, the RMCA has five (5) grants available for this year's 3-month training program (from 07 March up to 27 May 2016) in the use of FishBase and the taxonomy of African fishes. To apply for traineeship and for more information, see: http://fishbase.africamuseum.be or www.fishbaseforafrica.org. The training course will have three (3) subsets: A detailed explanation of FishBase in all its aspects; A training in the taxonomy of African fishes; A case study based on data from FishBase or on taxa for which taxonomic problems have been encountered. *For 2016, this course will be given in French only. Questions? Contact Dimitri Geelhand de Merxem (dimitri.geelhand@africamuseum.be). Full Article Events
axon Basics of Taxonomy: describing, illustrating and communicating biodiversity, a DEST course By www.eubon.eu Published On :: Mon, 13 Jun 2016 09:40:00 +0300 The 5th edition of the DEST course "Basics of Taxonomy" is co-organised with the Scandinavian Research School in Biosystematics (ForBio). The course will take place from 10 to 21 October 2016 at the Sven Lovén Centre for Marine Sciences, Kristineberg. Course topics covered: DELTA, digital drawing, scientific illustration, scientific writing and communication, Scratchpads. For more infromation and to register, please go to: http://taxonomytraining.eu/content/basics-taxonomy-describing-illustrating-and-communicating-biodiversity-0 Full Article Events
axon Integrating and visualizing primary data from prospective and legacy taxonomic literature By www.eubon.eu Published On :: Wed, 13 May 2015 11:28:42 +0300 Full Article Events
axon PESI - a taxonomic backbone for Europe By www.eubon.eu Published On :: Fri, 02 Oct 2015 15:08:37 +0300 Full Article Events
axon Utilizing online resources for taxonomy: a cybercatalog of Afrotropical apiocerid flies (Insecta: Diptera: Apioceridae) By www.eubon.eu Published On :: Mon, 12 Oct 2015 14:47:21 +0300 Full Article Events
axon How Aphia—The Platform behind Several Online and Taxonomically Oriented Databases—Can Serve Both the Taxonomic Community and the Field of Biodiversity Informatics By www.eubon.eu Published On :: Tue, 22 Dec 2015 09:07:40 +0200 Full Article Events
axon Linking Earth Observation and taxonomic, structural and functional biodiversity: Local to ecosystem perspectives By www.eubon.eu Published On :: Tue, 27 Sep 2016 14:55:40 +0300 Full Article Events
axon D1.4 Summary report of operational EU BON services and data provision for the European taxonomic backbone By www.eubon.eu Published On :: Tue, 22 Nov 2016 14:46:00 +0200 Full Article Events
axon Taxonomic sufficiency and indicator taxa reduce sampling costs and increase monitoring effectiveness for ants By www.eubon.eu Published On :: Mon, 15 May 2017 15:36:34 +0300 Full Article Events
axon Axon Completes Deal to Acquire Dedrone By www.sdmmag.com Published On :: Sun, 06 Oct 2024 19:06:59 -0400 Axon said the transaction will enable it to advance drone as first responder programs and safeguard against unauthorized threats posed by unmanned aircraft systems. Full Article
axon Axon Announces Campbell P.D. Secured Waiver for 24/7 DFR Operations By www.sdmmag.com Published On :: Sat, 19 Oct 2024 17:00:00 -0400 According to the announcement, DFR programs are changing how emergencies are handled by providing real-time situational awareness that improves response times and safety. Full Article
axon Anglo-Saxons' plans for Afghanistan have never changed By english.pravda.ru Published On :: Fri, 01 Oct 2021 19:40:00 +0300 At the beginning of the last century, the news about the death of Afghan Emir Abdur-Rahman made headlines all over the world. It was reported that his death could lead to most unpleasant consequences for both Russia and England, and, consequently, for the whole world politics. Kabul - Russia - Kabul Everything flows, but nothing changes. The topic of the Afghanistan crisis has become important again, especially for Russia. England is no longer the same, and the successor - the United States - is a far cry from the current rulers of Afghanistan. After Shir Ali Khan's accession to the throne in 1864, Abdur-Rahman participated in the troops of his father, Afzul Khan, and uncle Azim Khan in the fight against his other uncle, the powerful Emir Shir Ali. He conquered Kabul in 1866, where his father established himself. Full Article History traditions
axon Society for Scholarly Publishing picks Access Innovations, Inc. for taxonomy and auto tagging services By www.kmworld.com Published On :: Fri, 05 Jan 2024 11:00:52 EST Tagging the content at the article and sub-article level will make it easier to surface content more precisely relevant to the SSP community Full Article
axon SE Radio 592: Jaxon Repp on Distributed Data Infrastructure By se-radio.net Published On :: Thu, 30 Nov 2023 00:57:00 +0000 Jaxon Repp of HarperDB speaks with Brijesh Ammanath about distributed data infrastructure, including what it is and why it's important. They discuss the key factors that make distributed data infrastructure attractive, as well as challenges to implementing it. The episode explores the architecture and design principles, the key security considerations, and the transition factors for distributed data Infrastructure. Brought to you by IEEE Computer Society and IEEE Software. Full Article
axon SE Radio 594: Sean Moriarity on Deep Learning with Elixir and Axon By se-radio.net Published On :: Thu, 14 Dec 2023 22:49:00 +0000 Sean Moriarity, creator of the Axon deep learning framework, co-creator of the Nx library, and author of Machine Learning in Elixir and Genetic Algorithms in Elixir, published by the Pragmatic Bookshelf, speaks with SE Radio host Gavin Henry about what deep learning (neural networks) means today. Using a practical example with deep learning for fraud detection, they explore what Axon is and why it was created. Moriarity describes why the Beam is ideal for machine learning, and why he dislikes the term “neural network.” They discuss the need for deep learning, its history, how it offers a good fit for many of today’s complex problems, where it shines and when not to use it. Moriarity goes into depth on a range of topics, including how to get datasets in shape, supervised and unsupervised learning, feed-forward neural networks, Nx.serving, decision trees, gradient descent, linear regression, logistic regression, support vector machines, and random forests. The episode considers what a model looks like, what training is, labeling, classification, regression tasks, hardware resources needed, EXGBoost, Jax, PyIgnite, and Explorer. Finally, they look at what’s involved in the ongoing lifecycle or operational side of Axon once a workflow is put into production, so you can safely back it all up and feed in new data. Brought to you by IEEE Computer Society and IEEE Software magazine. This episode sponsored by Miro. Full Article
axon Axonis Therapeutics bags $115m for neuromedicine development By www.siliconrepublic.com Published On :: Thu, 31 Oct 2024 11:08:56 +0000 The funds will also enable the development of next generation compounds, according to the company. Read more: Axonis Therapeutics bags $115m for neuromedicine development Full Article Start-ups biotech funding and investment medicine neuroscience
axon Nuclear, gas and green finance taxonomies in the EU and UK By www.chathamhouse.org Published On :: Thu, 20 Jan 2022 17:07:14 +0000 Nuclear, gas and green finance taxonomies in the EU and UK 23 February 2022 — 10:00AM TO 11:00AM Anonymous (not verified) 20 January 2022 Online Experts discuss EU, UK, and international perspectives on green taxonomy. This event will address the controversial additions to the EU green finance taxonomy, including the labelling of some nuclear and gas power sources as “green”. Hear perspectives from the UK, EU and international experts. The UK has committed to creating a green taxonomy to provide a shared understanding of which economic activities count as sustainable. It should be robust and evidence-based, taking an objective and science-based approach to assessing sustainability. Technical Screening Criteria (TSCs) for the climate change mitigation, and climate change adaptation objectives within the UK green taxonomy will be based on those in the EU Taxonomy. The Government is currently reviewing these and expects to consult on UK draft TSCs in the first quarter of 2022, ahead of legislating by the end of 2022. In recent weeks the European Commission has proposed controversial additional TSCs for the EU taxonomy, most notably the inclusion of nuclear and natural gas in power generation, which are currently being discussed by Member States and the European Parliament. The inclusion of controversial power sources not only risks affecting investment and deployment patterns in the net-zero transition, but may also be a threat to the authority of the taxonomy as a whole Key questions for the UK now include whether and how to address these issues in its own taxonomy, and how to promote a science-based ‘race to the top’ between jurisdictions that can lead to robust international standards. This Environment and Society Discussion Series event brings expert voices together to discuss EU, UK, and international perspectives, and is co-organized with E3G. Full Article
axon Proteomics and Metaproteomics Add Functional, Taxonomic and Biomass Dimensions to Modeling the Ecosystem at the Mucosal-luminal Interface [Review] By www.mcponline.org Published On :: 2020-09-01T00:05:24-07:00 Recent efforts in gut microbiome studies have highlighted the importance of explicitly describing the ecological processes beyond correlative analysis. However, we are still at the early stage of understanding the organizational principles of the gut ecosystem, partially because of the limited information provided by currently used analytical tools in ecological modeling practices. Proteomics and metaproteomics can provide a number of insights for ecological studies, including biomass, matter and energy flow, and functional diversity. In this Mini Review, we discuss proteomics and metaproteomics-based experimental strategies that can contribute to studying the ecology, in particular at the mucosal-luminal interface (MLI) where the direct host-microbiome interaction happens. These strategies include isolation protocols for different MLI components, enrichment methods to obtain designated array of proteins, probing for specific pathways, and isotopic labeling for tracking nutrient flow. Integration of these technologies can generate spatiotemporal and site-specific biological information that supports mathematical modeling of the ecosystem at the MLI. Full Article
axon On Myelinated Axon Plasticity and Neuronal Circuit Formation and Function By www.jneurosci.org Published On :: 2017-10-18 Rafael G. AlmeidaOct 18, 2017; 37:10023-10034Viewpoints Full Article
axon Neuritin Controls Axonal Branching in Serotonin Neurons: A Possible Mediator Involved in the Regulation of Depressive and Anxiety Behaviors via FGF Signaling By www.jneurosci.org Published On :: 2024-10-09T09:30:20-07:00 Abnormal neuronal morphological features, such as dendrite branching, axonal branching, and spine density, are thought to contribute to the symptoms of depression and anxiety. However, the role and molecular mechanisms of aberrant neuronal morphology in the regulation of mood disorders remain poorly characterized. Here, we show that neuritin, an activity-dependent protein, regulates the axonal morphology of serotonin neurons. Male neuritin knock-out (KO) mice harbored impaired axonal branches of serotonin neurons in the medial prefrontal cortex and basolateral region of the amygdala (BLA), and male neuritin KO mice exhibited depressive and anxiety-like behaviors. We also observed that the expression of neuritin was decreased by unpredictable chronic stress in the male mouse brain and that decreased expression of neuritin was associated with reduced axonal branching of serotonin neurons in the brain and with depressive and anxiety behaviors in mice. Furthermore, the stress-mediated impairments in axonal branching and depressive behaviors were reversed by the overexpression of neuritin in the BLA. The ability of neuritin to increase axonal branching in serotonin neurons involves fibroblast growth factor (FGF) signaling, and neuritin contributes to FGF-2-mediated axonal branching regulation in vitro. Finally, the oral administration of an FGF inhibitor reduced the axonal branching of serotonin neurons in the brain and caused depressive and anxiety behaviors in male mice. Our results support the involvement of neuritin in models of stress-induced depression and suggest that neuronal morphological plasticity may play a role in controlling animal behavior. Full Article
axon TRIM46 Is Required for Microtubule Fasciculation In Vivo But Not Axon Specification or Axon Initial Segment Formation By www.jneurosci.org Published On :: 2024-10-16T09:30:18-07:00 Vertebrate nervous systems use the axon initial segment (AIS) to initiate action potentials and maintain neuronal polarity. The microtubule-associated protein tripartite motif containing 46 (TRIM46) was reported to regulate axon specification, AIS assembly, and neuronal polarity through the bundling, or fasciculation, of microtubules in the proximal axon. However, these claims are based on TRIM46 knockdown in cultured neurons. To investigate TRIM46 function in vivo, we examined male and female TRIM46 knock-out mice. Contrary to previous reports, we find that TRIM46 is dispensable for axon specification and AIS formation. TRIM46 knock-out mice are viable, have normal behavior, and have normal brain structure. Thus, TRIM46 is not required for AIS formation, axon specification, or nervous system function. However, we confirm that TRIM46 is required for microtubule fasciculation. We also show TRIM46 enrichment in the first ~100 μm of axon occurs independently of ankyrinG (AnkG) in vivo, although AnkG is required to restrict TRIM46 only to the AIS. Our results highlight the need for further investigation of the mechanisms by which the AIS and microtubules interact to shape neuronal structure and function. Full Article
axon Synaptotagmin 4 Supports Spontaneous Axon Sprouting after Spinal Cord Injury By www.jneurosci.org Published On :: 2024-10-23T09:30:30-07:00 Injuries to the central nervous system (CNS) can cause severe neurological deficits. Axonal regrowth is a fundamental process for the reconstruction of compensatory neuronal networks after injury; however, it is extremely limited in the adult mammalian CNS. In this study, we conducted a loss-of-function genetic screen in cortical neurons, combined with a Web resource-based phenotypic screen, and identified synaptotagmin 4 (Syt4) as a novel regulator of axon elongation. Silencing Syt4 in primary cultured cortical neurons inhibits neurite elongation, with changes in gene expression involved in signaling pathways related to neuronal development. In a spinal cord injury model, inhibition of Syt4 expression in cortical neurons prevented axonal sprouting of the corticospinal tract, as well as neurological recovery after injury. These results provide a novel therapeutic approach to CNS injury by modulating Syt4 function. Full Article