artemis

Denmark becomes 48th nation to sign Artemis Accords for space exploration

Denmark is a founding member of the European Space Agency and on Wednesday formally committed to safe and responsible space exploration that benefits humanity by signing the Artemis Accords.





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Artemis – CERT Polska bada bezpieczeństwo polskiego internetu

Nowy Rok przyniósł kolejne rozwiązania poprawiające bezpieczeństwo polskiego internetu. Jednym z nich jest Artemis – narzędzie rozwijane przez zespół CERT Polska, które pomaga sprawdzać poziom zabezpieczeń stron internetowych. Weryfikacji podlegają podmioty, w przypadku których, zgodnie z ustawą o krajowym systemie cyberbezpieczeństwa, obsługa incydentów koordynowana jest przez CSIRT NASK.




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Artemis działa już rok - sprawdź efekty

Rok 2023 to kolejne działania CERT Polska poprawiające bezpieczeństwo polskiego internetu. Jednym z zainicjowanych w tym czasie projektów był Artemis. Dwanaście miesięcy działania dało imponujące efekty - przeskanowaliśmy ponad 50 tys. domen i adresów IP, odkrywając blisko 180 tys. podatności lub błędnych konfiguracji.




artemis

S. Korea, US to Conduct Joint Studies for Artemis Moon Exploration Program

[Science] :
South Korea and the United States will conduct joint studies related to the Artemis moon exploration program. According to the Korea AeroSpace Administration on Wednesday, it has signed a study agreement on the Artemis program with U.S. National Aeronautics and Space Administration(NASA). The agreement ...

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artemis

NASA Artemis Moon landing delayed by 'several years' as costs go 'underreported'

NASA Artemis Moon landing delayed by 'several years' as costs go 'underreported'




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Астроновости: сюрприз микроквазара SS433, подробности миссии Artemis 3, пик солнечной активности…

Группа радиоастрономов под руководством Сергея Тюльбашева, работающая в Пущинской обсерватории, обнаружила необычный радиоимпульс длительностью 211 мс с показателем дисперсии около 134,4 пк/см³ на частоте 111 МГц. Этому импульсу присвоено обозначение FRB 20190203.
28 октября NASA предоставила обновленный список из девяти возможных мест посадки на Луне для миссии Artemis 3. Каждый из этих объектов отличается своим уникальным геологическим разнообразием, что открывает новые горизонты для изучения лунных ресурсов и истории нашей Солнечной системы.
В новом исследовании, проведенном с помощью космического телескопа «Джеймс Уэбб» международной группой ученых, ведомой астрономами из Университета штата Пенсильвания, было выяснено, что некоторые из протопланетных дисков, изначально обнаруженных «Хабблом», окружают коричневые карлики — звездные объекты, которые слишком малы и холодны, чтобы в них происходил синтез водорода. Новые результаты, полученные «Уэббом», помогут астрономам лучше понять, как формируются коричневые карлики, как они связаны с другими звездами и планетами и есть ли у них быть собственные спутники.
В ходе телеконференции с журналистами Национальное управление океанических и атмосферных исследований США (NOAA) и Международная группа по прогнозированию солнечных циклов объявили о достижении Солнцем периода максимума, который продлится в течение следующего года. Каждый из 11-летних циклов характеризуется сменой магнитных полюсов Солнца, что приводит к переходу звезды из спокойного состояния в активное. Затем активность постепенно снижается до минимума, однако ученые не могут точно предсказать, в какой именно момент это произойдет.
Изображение номера — микроквазар SS433.

Сообщение Астроновости: сюрприз микроквазара SS433, подробности миссии Artemis 3, пик солнечной активности… появились сначала на Троицкий вариант — Наука.




artemis

NASA’s Artemis I moon rocket finally launches

NASA’s massive SLS rocket and Orion spacecraft kick off a series of missions to put humans back on the Moon.




artemis

Cyprus signs NASA's Artemis Accords, becoming 46th nation to commit to safe space exploration

The Mediterranean island nation of Cyprus signed the U.S.-led Artemis Accords on Wednesday, becoming the 46th signatory to the agreement that establishes principles for the safe exploration of space.




artemis

NASA identifies nine possible landing regions for Artemis III moon mission

NASA has identified nine possible landing sites for its Artemis III mission in September 2026 that will return astronauts to the moon for the first time in more than 50 years, the space agency announced Monday.




artemis

Inside the Epic Artemis Moon Missions

The Artemis program represents the pinnacle of NASA's mind-boggling technological capabilities. Learn about the groundbreaking achievements and breathtaking lunar landscapes that await us in this new era of space exploration. --- For more videos from Smithsonian Magazine: https://www.smithsonianmag.com/videos/ Digital Editorial Director: Brian Wolly Supervising Producer & Scriptwriter: Michelle Mehrtens Video Editor: Sierra Theobald




artemis

Total synthesis of artemisinin

The present invention provides a method for manufacturing artemisinin and its congeners from cyclohexenone as a starting material.




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Sir Ben Ainslie gets Land Rover BAR back on track with win over Artemis Racing

Sir Ben Ainslie steered Land Rover BAR back to winning ways in the America's Cup Qualifiers on Tuesday by comfortably beating Sweden's Artemis Racing in Bermuda.




artemis

Significant efficacy of single low dose primaquine compared to stand alone artemisinin combination therapy in reducing gametocyte carriage in Cambodian patients with uncomplicated multidrug resistant Plasmodium falciparum malaria [Epidemiology and Surveil

Since 2012, single low dose of primaquine (SLDPQ, 0.25mg/kg) has been recommended with artemisinin-based combination therapies, as first-line treatment of acute uncomplicated Plasmodium falciparum malaria, to interrupt its transmission, especially in low transmission settings of multidrug, including artemisinin, resistance. Policy makers in Cambodia have been reluctant to implement this recommendation due to primaquine safety concerns and lack of data on its efficacy.

In this randomized controlled trial, 109 Cambodians with acute uncomplicated P. falciparum malaria received dihydroartemisinin-piperaquine (DP) alone or combined with SLDPQ on the first treatment day. Transmission-blocking efficacy of SLDPQ was evaluated on Days 0, 1, 2, 3, 7, 14, 21, 28 and recrudescence by reverse transcriptase polymerase chain reaction (RT-PCR) (gametocyte prevalence) and membrane-feeding assays with Anopheles minimus mosquitoes (gametocyte infectivity). Without the influence of recrudescent infections, DP+SLDPQ reduced gametocyte carriage 3 fold compared to DP. Of 48 patients tested on Day 0, only three patients were infectious to mosquitoes (~6%). Post-treatment, three patients were infectious: on D14 (3.5%, 1/29), and on the first and seventh day of recrudescence (8.3%, 1/12 for each); this overall low infectivity precluded our ability to assess its transmission blocking efficacy.

Our study confirms effective gametocyte clearance of SLDPQ when combined with DP in multidrug resistant P. falciparum and the negative impact of recrudescent infections due to poor DP efficacy. Artesunate-mefloquine (ASMQ) has replaced DP and ASMQ-SLDPQ has been deployed to treat all P. falciparum symptomatic patients to further support the elimination of multidrug resistant P. falciparum in Cambodia.




artemis

Experimentally engineered mutations in a ubiquitin hydrolase, UBP-1, modulate in vivo susceptibility to artemisinin and chloroquine in Plasmodium berghei. [Mechanisms of Resistance]

As resistance to artemisinins (current frontline drugs in malaria treatment) emerges in south East Asia, there is an urgent need to identify the genetic determinants and understand the molecular mechanisms underpinning such resistance. Such insights could lead to prospective interventions to contain resistance and prevent the eventual spread to other malaria endemic regions. Artemisinin reduced susceptibility in South East Asia (SEA) has been primarily linked to mutations in P. falciparum Kelch-13, which is currently widely recognised as a molecular marker of artemisinin resistance. However, 2 mutations in a ubiquitin hydrolase, UBP-1, have been previously associated with artemisinin reduced susceptibility in a rodent model of malaria and some cases of UBP-1 mutation variants associating with artemisinin treatment failure have been reported in Africa and SEA. In this study, we have employed CRISPR-Cas9 genome editing and pre-emptive drug pressures to test these artemisinin susceptibility associated mutations in UBP-1 in P. berghei sensitive lines in vivo. Using these approaches, we have shown that the V2721F UBP-1 mutation results in reduced artemisinin susceptibility, while the V2752F mutation results in resistance to chloroquine and moderately impacts tolerance to artemisinins. Genetic reversal of the V2752F mutation restored chloroquine sensitivity in these mutant lines while simultaneous introduction of both mutations could not be achieved and appears to be lethal. Interestingly, these mutations carry a detrimental growth defect, which would possibly explain their lack of expansion in natural infection settings. Our work has provided independent experimental evidence on the role of UBP-1 in modulating parasite responses to artemisinin and chloroquine under in vivo conditions.




artemis

Exclusive: Trump administration drafting 'Artemis Accords' pact for moon mining - sources

The Trump administration is drafting a legal blueprint for mining on the moon under a new U.S.-sponsored international agreement called the Artemis Accords, people familiar with the proposed pact told Reuters.




artemis

University of Washington wins NASA grant to create spacey contest for Artemis Student Challenges

NASA has awarded the University of Washington a $499,864 grant to develop a competition that calls on students to turn a simulated lava tube into a habitat suitable for harboring humans on the moon or Mars. The exploration and habitation skills competition will be funded as part of NASA's Artemis Student Challenges program, which plays off the themes of the Artemis moon program to inspire the next generation of explorers and engineers. The competition will involve navigating a rover through a facsimile lava tube and surface structures, generating maps, identifying valuable resources and deploying an airtight barrier to seal the… Read More





artemis

Artemis Accords: Trump to draft legal space pact to allow mining on the moon

The agreement would be the latest effort to cultivate allies around NASA’s plan to put humans and space stations on the moon within the next decade, and comes as the civilian space agency plays a growing role in implementing American foreign policy.




artemis

The mysterious Artemis Accords describe US interests in space resources

NASA added the name of the goddess Artemis to new missions. TWH examines some possible implications of the secretive "Artemis Accords" and how they relate to previous treaties and agreements that pertain to space and celestial bodies.

Continue reading The mysterious Artemis Accords describe US interests in space resources at The Wild Hunt.




artemis

More Antimalarial Artemisinin can Be Extracted from Chinese Shrubs

iArtemisia annua/i herb has now been genetically engineered to produce more Artemisinin. Anti-Malarial benefits of Artemisinin compound can only be




artemis

The Voice: Thunderstorm Artemis scores four-chair turn with Beatles cover and chooses John Legend

Hawaiian singer Thunderstorm Artis scored a four-chair turn on Monday's episode of The Voice wowing the coaches with his moving rendition of Blackbird by the Beatles.




artemis

NASA releases defiant video outlining details of Artemis moon mission

The US national space agency asked for $1.4 billion to create the lunar lander that would take astronauts to the surface of the moon by 2024 - they've been given $600 million.




artemis

A group of new astronauts join NASA under the Artemis program and could be the first to step on Mars

It's been more than two years in the making, but 13 astronauts have finally joined NASA under the mission that will bring the first female to the moon and some may be the first humans to step on Mars.




artemis

NASA reveals plans for 'Artemis Base Camp' on the moon that help astronauts get ready for Mars

NASA has released a detailed plan for an 'Artemis Base Camp' that will be home to first woman and next man on the moon in 2024, which will help the crew prepare for the journey to Mars.




artemis

NASA chooses SpaceX, Blue Origin and Dynetics to design human landing systems for Artemis mission

NASA 's Artemis mission has turned into a space race between billionaires, as Jeff Bezos' Blue Origin and Elon Musk's SpaceX have been chosen to develop human landing systems for mission.




artemis

NASA Lunar Gateway For Artemis Program To Be Ready By 2023

NASA Artemis Program is one of the much-anticipated missions to explore the Moon. As part of the mission, NASA is working on the Lunar Gateway project, which will serve as a space station for scientific experiments on the Moon. The NASA




artemis

The trials of spring / Fork Films presents ; producer, Beth Levison ; director, Gini Reticker ; a co-production of ZAG Line Pictures, LLC and Independent Television Service (ITVS) ; in association with Fork Films, Artemis Rising Foundation and Center For

Rotch Library - JQ1850.A91 T75 2015




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Ethical issues in clinical forensic psychiatry Artemis Igoumenou, editor

Online Resource




artemis

[ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00669




artemis

[ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00131




artemis

[ASAP] A Chemically Stable Fluorescent Mimic of Dihydroartemisinin, Artemether, and Arteether with Conserved Bioactivity and Specificity Shows High Pharmacological Relevance to the Antimalarial Drugs

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00430




artemis

[ASAP] <italic toggle="yes">Plasmodium falciparum</italic> Artemisinin Resistance: The Effect of Heme, Protein Damage, and Parasite Cell Stress Response

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00527




artemis

In vivo and in vitro evaluation of dihydroartemisinin prodrug nanocomplexes as a nano-drug delivery system: characterization, pharmacokinetics and pharmacodynamics

RSC Adv., 2020, 10,17270-17279
DOI: 10.1039/D0RA02150D, Paper
Open Access
Guolian Ren, Pei Chen, Jiaqi Tang, Wenju Guo, Rongrong Wang, Ning Li, Yujie Li, Guoshun Zhang, Ruili Wang, Shuqiu Zhang
To develop new, more effective and lower toxicity antitumor dihydroartemisinin (DHA) nanocomplexes, a DHA prodrug synthesized in this study was used to prepare DHA prodrug self-assembled nanocomplexes (DHANPs) by molecular self-assembly technology.
The content of this RSS Feed (c) The Royal Society of Chemistry




artemis

[ASAP] Bioactive <italic toggle="yes">seco</italic>-Sativene Sesquiterpenoids from an <italic toggle="yes">Artemisia desertorum</italic> Endophytic Fungus, <italic toggle="yes">Cochliobolus sativ

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01148




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[ASAP] Crystallization-Induced Diastereoisomer Transformation of Dihydroartemisinic Aldehyde with the Betti Base

Organic Process Research & Development
DOI: 10.1021/acs.oprd.9b00481




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Artemisinin-based combination therapy (ACTs) drug resistance trends in Plasmodium falciparum isolates in Southeast Asia




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Chemical investigation of the antarctic marine invertebrates _synoicum adareanum_ and _artemisina plumosa_




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Artemisia gentileschi :




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Colossal Head of Artemis




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Ares, Aphrodite, Artemis, Apollo and Zeus Watching the Trojan War




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Ares, Aphrodite, Artemis, Apollo and Zeus Watching the Trojan War




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Poseidon, Apollo and Artemis. from E Frieze of Parthenon




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Poseidon, Apollo and Artemis. from E Frieze of Parthenon




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Poseidon, Apollo and Artemis. from E Frieze of Parthenon




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Artemis




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Artemis




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Torso of Artemis




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Torso of Artemis