These are the FE editorial picks from the past year that best exemplify advances in the alternative protein space, from facilities to flavor.

The University of Kentucky Sanders-Brown Center on Aging Director Linda Van Eldik, Ph.D., hopes to shed light on how specific brain cells may contribute to the progression of Alzheimer's disease, paving the way for potential new therapeutic approaches.Van Eldik recently received a three-year, $300,000 award from the BrightFocus Foundation to support her research project, "Relationship between astrocyte p38 MAPK, neuroinflammation, and Alzheimer pathology.

Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to a New England Journal of Medicine editorial published by Matthew Milowsky, MD, FASCO, a bladder cancer expert at UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center.

Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to a New England Journal of Medicine editorial published by Matthew Milowsky, MD, FASCO, a bladder cancer expert at UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center.

In an age where academic degrees may be literally printed from home, some experts are calling for the development of minimum requirements to accredit academic programs in the occupational safety and health (OSH) profession. 

6 different treatment options to help ease and manage symptoms of vertigo from medications to natural remedies.

Medical science in the 21st century is making strides in areas that once seemed like science fiction. As technology rapidly advances, we’re seeing new possibilities for improving health and longevity. From potential treatments for tooth loss to progress in curing genetic disorders, these innovations aim to address some of the significant health challenges we face […]

The post 10 Major Recent Advances in Medicine appeared first on Listverse.

Welcome back to another episode of the Niche Pursuits News Podcast! This week Jared and guest host Brooks talk about what’s happening in the SEO, Google, and AI world, they share the projects they’re working on, and they discuss some…

The post AI Advances! A Look at August Core Update Data appeared first on Niche Pursuits.

Coco Gauff confirms her semi-final spot at the WTA Finals with a rare win over defending champion Iga Swiatek.

This paper explores innovative ideas and strategies for promoting environmental sustainability within the hotel industry, with the goal of streamlining these concepts for practical application in the industry and facilitating future academic research. The research methodology encompassed extensive online desk research, yielding a collection of 87 articles that were subject to thorough analysis. Additionally, personal consultations were conducted with industry experts to align their insights with the identified innovative ideas. To facilitate comprehension, appropriate terminology was assigned to these concepts. Subsequently, a post-discussion phase was conducted, engaging in one-on-one sessions with five industry experts to distil these insights into four distinct directions. This paper holds potential value for both industry stakeholders and academics, serving as a structured compendium of ideas and innovations crucial for advancing sustainability in the hotel sector. Moreover, it provides a solid foundation for further academic research.

Using information criteria is a common method for making a decision about which model to use for forecasting. There are many different methods for evaluating forecasting models, such as MAE, RMSE, MAPE, and Theil-U, among others. After the creation of AIC, AICc, HQ, BIC, and BICc, the two criteria that have become the most popular and commonly utilised are Bayesian IC and Akaike's IC. In this investigation, we are innovative in our use of exponential weighting to get the log-likelihood of the information criteria for model selection, which means that we propose assigning greater weight to more recent data in order to reflect their increased precision. All research data is from the major stock markets' daily observations, which include the USA (GSPC, DJI), Europe (FTSE 100, AEX, and FCHI), and Asia (Nikkei).

China's military is advancing the development of high-technology arms, including sound weapons to wage cognitive warfare -- the use of unconventional tools and capabilities to alter enemy thinking and decision-making, according to a new open-source intelligence report.

Katie Boulter has overcome a series of mediocre results on the WTA Tour's Asian swing to advance to the Pan Pacific Open semifinals with a 6-2, 6-1 win over Bianca Andreescu on Friday.

Former Australian Open champion Sofia Kenin has advanced to the final of the Pan Pacific Open with a 6-4, 6-4 win over ninth-seeded Katie Boulter on Saturday.

Alexei Popyrin upset fourth-seeded Daniil Medvedev 6-4, 2-6, 7-6 (4) in the second round of the Paris Masters on Wednesday in a tense match with many ups and downs.

Home management solutions continue to see significant advancements, offering consumers enhanced convenience, security and energy efficiency.

Olivet, Mich., has 1,250 students enrolled in its three Olivet Community Schools.

Olympia, WA — Legislation that would restore Washington state regulations requiring employers to establish practices intended to prevent work-related musculoskeletal disorders was approved by the state House on Feb. 15.

Providence, RI — The Rhode Island Senate recently passed legislation aimed at protecting workers from psychological abuse – such as bullying – on the job.

Washington — The House Appropriations Committee has approved legislation that would prohibit funding for a Federal Motor Carrier Safety Administration proposal to require the installation of speed-limiting devices on heavy trucks.

Tallahassee, FL — A bill that would roll back restrictions on the number of hours 16- and 17-year-olds can work, and when, is advancing in the Florida Legislature.

Frankfort, KY — A bill that would allow 16- and 17-year-olds to work longer and later hours, among other child labor law rollbacks, is advancing in the Kentucky Legislature.

In this interview with Prepared Foods, Eyal Rosenthal, CEO of Ever After Foods, Ltd., discusses the company’s advancements in cell-based meat production. Learn how Ever After's technology eschewed the industry standard and is able to produce a high volume, so-far comparatively low cost product.

Food and beverage intelligence company Datassential enhanced its limited-time offer (LTO) and item launches solution, allowing users to seamlessly track new menu items and LTOs at nearly 300 top chains through an easy-to-use user interface (UI), enhanced analytics, and ability to overlay consumer ratings.

Building materials manufacturer LX Hausys has released its 2024 ESG Report, highlighting significant environmental progress at its Georgia facilities. 

Non Destructive Testing (NDT) of materials and structures is one of the most common forms of quality control. The Nigerian infrastructure systems continue to deteriorate due to lack of integrity checks on some identified projects in both public and private sector. Analysis of various sectors in Nigeria revealed that there are abandon projects in building and constructions industry while majo...

Source: Streetwise Reports 11/08/2024

Vertex Pharmaceuticals Inc. (VRTX:NASDAQ) has reported a robust financial performance for the third quarter of 2024. The report has demonstrated the company's continued revenue growth and the strengthening of its innovative pipeline. For Q3 2024, Vertex's product revenue reached US$2.77 billion, a 12% increase from the previous year. This was primarily driven by strong demand for its TRIKAFTA®/KAFTRIO® therapies. Based on this momentum, Vertex raised its full-year product revenue guidance to a range of US$10.8 billion to US$10.9 billion, citing a solid trajectory in its cystic fibrosis (CF) portfolio and expected future launches.

In Q3, the company made notable advancements in its pipeline. Three programs have begun moving into Phase 3 clinical development: suzetrigine in diabetic peripheral neuropathy (DPN), povetacicept in IgA nephropathy (IgAN), and VX-880 in type 1 diabetes (T1D). Vertex is also preparing for the launch of two potential treatments in early 2025, with PDUFA dates set for January 2 for the vanzacaftor triple therapy for CF and January 30 for suzetrigine, the latter being a pain medication in a new therapeutic class aimed at reducing reliance on opioids.

GAAP and Non-GAAP net income both reached US$1.0 billion, largely driven by increased product revenue, which offset rising R&D and SG&A expense. This was s due to investments in global commercialization and late-stage clinical development. For Q3, Vertex's combined R&D and SG&A expenses were US$1.2 billion and US$1.1 billion, respectively, an increase from last year attributed to new global program advancements and upcoming launch support.

Vertex's cash position remained strong, with US$11.2 billion in cash, cash equivalents, and marketable securities as of September 30. The decline from US$13.7 billion at the end of 2023 primarily reflects the acquisition of Alpine Immune Sciences and share repurchases under the company's buyback program.

A Look At Biotechnology and Pharma

The U.S. Pharmaceuticals Report for 2024 by Nova One Advisor detailed the size and growth trajectory of the U.S. pharmaceutical market. Valued at US$602.19 billion in 2023, the sector is projected to exceed US$1 trillion by 2033. The report pointed to a "high healthcare expenditure provided by government bodies" as a primary growth driver, further bolstered by the aging population's demand for advanced treatments.

In an October 24 article, The Investing News Network reported on a dynamic landscape within the biotechnology sector. The report highlighted advancements in AI-powered drug discovery. Despite a cautious investment climate, interest remained strong in AI's potential to reshape healthcare, with venture capital investment reaching US$6.59 billion. At the HealthTech Ignite conference, Susie Roberts from Relay Therapeutics expressed confidence, noting, "We will definitely see AI design drugs in the next 10 years."

On November 4, Yahoo! Finance shared insights from MIT professors Andrew Lo and Dennis Whyte. They emphasized that biotechnology's rapid advancement over the past five decades offers valuable lessons for future innovation. In their research paper, Lo and Whyte proposed initiatives to accelerate biotechnology's growth, underscoring the importance of "reducing risk and uncertainty" to foster a robust investment ecosystem that supports groundbreaking discoveries.

Catalysts Driving Vertex Pharma

According to Vertex's November 2024 investor presentation, the company sees multiple growth catalysts over the next few years. Vertex aims to meet its goal of achieving "five launches in five years," focusing on expanding the treatable patient base in CF with vanzacaftor triple, addressing critical needs in sickle cell disease (SCD) and beta thalassemia (TDT) with CASGEVY, and launching suzetrigine for acute pain management.

Additionally, Vertex expects its expansive R&D pipeline to support long-term growth. This includes pivotal clinical trials for VX-880 in T1D, povetacicept in IgAN, and NaV1.8 pain inhibitors like suzetrigine, indicating a commitment to treating a range of chronic and life-threatening conditions with limited therapeutic options.

By driving advancements in CF therapies, diversifying its portfolio with novel pain treatments, and pursuing accelerated approvals for renal and blood-related disorders, Vertex is strategically positioning itself to sustain growth and achieve several near-term milestones.

What Are Experts Saying About Vertex?

In a November 5, 2024, H.C. Wainwright & Co. update, the analysts highlighted promising data from Vertex's recent Phase 2 trial for suzetrigine, which showed encouraging reductions in pain intensity. [OWNERSHIP_CHART-4085]

The analysts noted that suzetrigine's peripheral nervous system-specific mechanism could potentially address "a significant, unmet medical need worldwide" in non-opioid pain management. They set a price target of US$600.00, projecting Vertex's continued growth from its strong cystic fibrosis franchise and pipeline expansion.

From the November 7 Kingswood Capital Partners report, analysts noted Vertex Pharmaceuticals' "sustained execution" in advancing product development programs and achieving robust operating margins, enabling "continued, significant investments" in both its pipeline and commercial capabilities. The firm maintained a "Buy" rating with a 12-month target price of US$550.00, attributing this outlook to Vertex's deep cash resources and historical successes in clinical trials.

Ownership and Share Structure

According to Refinitiv, 95.44% of Vertex Pharmaceuticals is held by Institutions. The top among them are Capital World Investors at 10.37%, The Vanguard Group at 8.88%, BlackRock Institutional Trust with 5.49%, State Street Global Advisors (US) with 4.55%, and Fidelity Management and Research with 4.11%. Strategic Investors hold .12%. The rest is retail.

The company's market cap is US$129,395.59 million with 257.07 million free float shares. The 52 week range is US$341.90–$510.64.

Sign up for our FREE newsletter at: www.streetwisereports.com/get-news

Important Disclosures:

1) James Guttman wrote this article for Streetwise Reports LLC and provides services to Streetwise Reports as an employee.

2) This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company.

For additional disclosures, please click here.

( Companies Mentioned: VRTX:NASDAQ, )

Recent strides in biotechnology offer the promise of new and innovative applications -- from edible vaccines to protein-based electronics components.

Synthetic biology expands the possibilities for creating new weapons — including making existing bacteria and viruses more harmful — while decreasing the time required to engineer such organisms, concludes a new report by the National Academies of Sciences, Engineering, and Medicine.

Using nuclear propulsion technologies to support a human mission to Mars in 2039 will require NASA to pursue an aggressive and urgent technology development program, says a new report from the National Academies of Sciences, Engineering, and Medicine.

To maintain U.S. global leadership and meet societal challenges — including generating medical advances, furthering the energy transition, and making food and water safer and more sustainable — new investments, collaborations, and educational practices in the chemical engineering field are needed.

PITTSBURGH (September 2, 2016) ... The potential to develop "materials that compute" has taken another leap at the University of Pittsburgh's Swanson School of Engineering, where researchers for the first time have demonstrated that the material can be designed to recognize simple patterns. This responsive, hybrid material, powered by its own chemical reactions, could one day be integrated into clothing and used to monitor the human body, or developed as a skin for "squishy" robots.

read more

"Promising" and "remarkable" are two words U.S. Department of Energy's Ames Laboratory scientist Javier Vela uses to describe recent research results on organolead mixed-halide perovskites.

read more

The Peanut and Tree Nut Processors Association met with leaders in the Ivory Coast.

When shopping for packaging materials and technology, a snack or bakery pro can’t just drive down to the nearest mall or log onto Amazon to have something delivered to their front door. 

PACK EXPO 2024 offers snack and bakery pros the chance to dive into the latest packaging and processing solutions

Dough comes in many styles, and today's laminators and sheeters need to accommodate an increasing range of requirements.

Companies that make pans for the baking industry, whether for breads, baguettes, muffins, cookies, cakes, pies, etc., are focused on issues like larger sizes, a desire for energy and material efficiency, stick resistance, and the ability to help produce specialty and artisanal products.

Research highlights growing body of prune evidence connected to favorable bone health.

The facility at the Danmark Protein site will be able to convert 2.8MW of electricity into 8MW of heat.

How is the aging population changing product design? Builders and designers have been hearing from clients that homeowners now want to age-in-place, and they also want to renovate their existing homes to accommodate various generations living under one roof. The lack of housing stock and current mortgage and interest rates have contributed to this phenomenon. This shift in living has been a boon to the renovation industry, and it has given rise to innovations and building processes that elegantly combine technology and health benefits in the service of independence for elderly or anyone with physical challenges.

In an industry vastly dominated by men, construction is an area of our labor force that is slowly seeing change.

Fusing technological solutions, BZBGEAR and NDI transcend the boundaries of live streaming and broadcasting.

Sena Cinema's Advances Digital Cinema Remote Monitoring & Distribution with LYNX Technik yellobrik Technology

Discovery may propel advances in regenerative medicineTORONTO, ON – Consider the relationship between an air traffic controller and a pilot. The pilot gets the passengers to their destination, but the air traffic controller decides when the plane can take off and when it must wait. The same relationship plays out at the cellular level in […]

Toronto, ON – A team of students from the Evening MBA program at the University of Toronto’s Rotman School of Management have won the UofT quarterfinal qualifying round to advance to the regional finals of the Hult Prize, the world’s largest student competition for social entrepreneurs. Purifire, consisting of Daniel Weng, Andrea Lo, Nirusan Rajakulendran, […]