Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00323A, Paper

Bunty Sharma, Gurpreet Kaur, Ganga Ram Chaudhary, Santosh L. Gawali, P. A. Hassan
Developments in the field of photodynamic therapy (PDT) are being made by investigating appropriate photosensitizers (PSs) and enhancing the penetration effect of light by developing new metallocatanionic vesicles.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02056J, Paper

Yadu N. Vakkipurath Kodakkadan, Kristyna Idzakovicova, Josef Sepitka, Daniël ten Napel, Eric Safai, Petr Cigler, Frantisek Štěpánek, Ivan Rehor
We introduce a method for photolithographic synthesis of arbitrarily shaped microgels composed purely of a biopolymer of choice.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00187B, Paper

Yuping Hu, Xuechun Wang, Peng Zhao, Hao Wang, Wei Gu, Ling Ye
The accelerated O₂ release from CaO₂ catalyzed by MnO₂ nanozyme leads to a rapid and efficient hypoxia relief, an increased yield of ¹O₂, a down-regulated HIF-1α and VEGF, and eventually a super-efficient PDT.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00083C, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Irene Anton-Sales, Justin Christopher D'Antin, Jorge Fernández-Engroba, Victor Charoenrook, Anna Laromaine, Anna Roig, Ralph Michael
Bacterial nanocellulose exhibits valuable properties to act as a corneal bandage material in terms of conformability, suturability, durability and ease of manipulation in ophthalmological environments.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00175A, Paper

Mohamed F. Attia, Meenakshi Ranasinghe, Roman Akasov, Jeffrey N. Anker, Daniel C. Whitehead, Frank Alexis
Hybrid gold-polyester nanoparticles were synthesized by UV irradiation of a gold salt and photoinitiator encapsulated in a polyester nanoparticle. The resulting materials exhibit excellent cellular imaging and surface plasmon resonance properties.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00015A, Paper

Manisha Ahir, Priyanka Upadhyay, Avijit Ghosh, Sushmita Sarker, Saurav Bhattacharya, Payal Gupta, Swatilekha Ghosh, Sreya Chattopadhyay, Arghya Adhikary
Cationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual miRNA loading, efficient delivery and significantly inhibited tumor growth as well as retarded metastasis in triple-negative breast cancer.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01809C, Review Article

Jiajun Zhong, Yuexiong Yang, Liqiong Liao, Chao Zhang
The microenvironments that cells encounter with in vitro.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00331J, Communication

Yihang Wu, Yue Xiong, Ling Wang, Quanming Zhou, Linxian Li, Pavel A. Levkin, Gary Davidson, Liqian Gao, Wenbin Deng
A library of lipidoids self-assembling to liposomes exhibits excellent transfection efficiency in HEK 293T cells and mESCs with low cytotoxicity.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00372G, Paper

Yongbin Cao, Boshu Ouyang, Xiaowei Yang, Qin Jiang, Lin Yu, Shun Shen, Jiandong Ding, Wuli Yang
Tumors were effectively destroyed by a mild photothermal effect and the subsequent gas mechanical damage triggered by NIR-II light.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM90037K, Correction

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Zhilin Liu, Na Shen, Zhaohui Tang, Dawei Zhang, Lili Ma, Chenguang Yang, Xuesi Chen
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01990A, Paper

Taufiq Ahmad, Hayeon Byun, Hyeok Jun Shin, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Young Min Shin, Heungsoo Shin
Adenosine and its receptors have emerged as alternative targets to control cellular functions for bone healing.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00318B, Communication

Pengyuan Qi, Qianyuan Chen, Dong Tu, Songhuan Yao, Yupeng Zhang, Jike Wang, Conghua Xie, Chunxu Pan, Hao Peng
The potential role of borophene as a radiosensitizer in PT and BNCT was investigated.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00427H, Paper

Yangyang Ye, Xiang Zhang, Fei Xie, Bin Xu, Ping Xie, Ting Yang, Qian Shi, Chen-Yu Zhang, Yujing Zhang, Jiangning Chen, Xiaohong Jiang, Jing Li
CRISPR-Cas9 components delivered by engineered exosomes achieve genome editing in recipient cells.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00155D, Paper

Sergio Acosta, Arturo Ibañez-Fonseca, Conrado Aparicio, J. Carlos Rodríguez-Cabello
Protein-engineered polymers can be used as multivalent platforms for AMP tethering on implant surfaces as cytocompatible coatings with strong antibiofilm properties.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00466A, Paper

Peng Zhang, Yu Zhang, Xiaoya Ding, Chunsheng Xiao, Xuesi Chen
An efficient strategy to selectively promote nanoparticle accumulation in solid tumors was developed by encapsulating sildenafil in cisplatin-incorporated polymeric micelles.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00063A, Paper

Yuyang Xia, Hongying Bao, Jie Huang, Xiaodi Li, Chenggong Yu, Zhijun Zhang, Haishui Wang
A dual-labeling strategy integrating near-infrared-persistent luminescence and RfLuc-based bioluminescence imaging techniques has been developed to track the transplanted stem cells, deepening the understanding of the role played by stem cells in PF treatment.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00076K, Paper

Jungju Oh, Sang-Mi Kim, Eun-Hye Lee, Minkyung Kim, Youngki Lee, Seung Hwan Ko, Ji Hoon Jeong, Chang-Hwan Park, Minhyung Lee
Heme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00395F, Communication

Yue Hu, Yuyin Tang, Xiao-Jing Zhang, Xiao-Tong Yang, Ying-Ying Tang, Su Li, Linyu Hu, Peng Chen, Dong Zhu
Multi-functional and hierarchically structured silica nanospheres are rationally designed and fabricated, which encapsulate quantum dots to permit near infrared deep tissue imaging and are loaded with carcinoembryonic antigen messenger RNA (CEAmRNA) to enable stable and abundant antigen expression in DCs.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02017A, Paper

Teresa Dean, Nancy T. Li, Jose L. Cadavid, Laurie Ailles, Alison P. McGuigan
A novel 3D in vitro co-culture platform to explore the interactions between cancer-associated fibroblasts and tumour cells that drive increased tumour cell invasion and the impact of matrix density.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00003E, Paper

Jia Qu, Dengke Teng, Guoqing Sui, Shihui Guan, Yang Wang, Qimeihui Wang, Yuanqiang Lin, Haitao Ran, Zhigang Wang, Hui Wang
The advantages of PCM@Lip/IT NPs include mitochondrial-targeting, on-demand drug release, and prodrug activation by hypoxia with guidance/monitoring by PA and FL imaging.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00376J, Paper

Dawei Li, Jin Zhou, Mingming Zhang, Yuanzheng Ma, Yanyu Yang, Xue Han, Xing Wang
An alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy and bone regeneration.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00159G, Minireview

Nicole F. Steinmetz, Sierin Lim, Frank Sainsbury
Protein cages found in nature have evolved for a variety of purposes and this review focuses on how they are being co-opted for use in immunotherapy and therapeutic delivery.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01872G, Review Article

Ratchapol Jenjob, Treethip Phakkeeree, Daniel Crespy
Core–shell particles offer significant advantages in their use for bioimaging and biosensors.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01968E, Paper

Teng Zhang, Qingguang Wei, Hua Zhou, Wenhao Zhou, Daoyang Fan, Xinhong Lin, Zehao Jing, Hong Cai, Yan Cheng, Xiaoguang Liu, Weishi Li, Chunli Song, Yun Tian, Nanfang Xu, Yufeng Zheng, Zhongjun Liu
Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6A14V for treating MRSA bone infection and enhancing osteogenesis.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00134A, Paper

Kiheon Baek, Alexander David Noblett, Pengyu Ren, Laura J. Suggs
Doxorubicin is intercalated within the nanofibril structure of self-assembled nucleo-peptide hydrogels and injection leads to decrease in tumor volume and greater concentration of chemotherapeutic relative to soluble form.
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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00204F, Paper

Yongju He, Linjie Shao, Ibrahim Usman, Yao Hu, Anqiang Pan, Shuquan Liang, Hui Xu
The dilemma between tumor accumulation and renal clearance has severely limited the efficacy of mesoporous silica-based drug nanocarrier in cancer therapy. Herein, a pH-responsive dissociable mesoporous silica-based nanoplatform with efficient...
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00222D, Review Article

Natanael Fernandes, Carolina F. Rodrigues, André F. Moreira, Ilídio J. Correia
Cancer photothermal therapy (PTT) has captured the attention of researchers worldwide due to its localized and trigger-activated therapeutic effect.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00549E, Paper

Tianhong Teng, Ronggui Lin, Ziguo Lin, Kun Ke, Xianchao Lin, Maoen Pan, Da Zhang, Heguang Huang
Preparation of Abraxane@MoSe₂ and its PTT effect augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00278J, Paper

Qinghua Li, Zujian Feng, Huijuan Song, Jianhua Zhang, Anjie Dong, Deling Kong, Weiwei Wang, Pingsheng Huang
¹⁹ F MRI is able to precisely monitor the localization and quantify the degradation rate of implantable/injectable hydrogels in real-time and noninvasive manner, with no interference of endogenous background signals and limitation of penetration depth.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00188K, Paper

Ning Han, Ziyang Xu, Chunyan Cui, Yuan Li, Dongfei Zhang, Meng Xiao, Chuanchuan Fan, Tengling Wu, Jianhai Yang, Wenguang Liu
A tunicate-inspired gelatin-based hydrogel prepared by a simple mixing method, exhibits strong adhesion and antibacterial capacity, and facilitates wound healing.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00147C, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Junxiong Qiu, Peng Peng, Min Xin, Zhenkang Wen, Zhong Chen, Sipeng Lin, Manyuan Kuang, Yuan Fu, Guibin Fang, Shixun Li, Changchuan Li, Jiaji Mao, Ling Qin, Yue Ding
Aseptic loosening (AL) caused by wear particles released from implant surfaces is one of the main causes for the failure of artificial joints, which is initiated by macrophage inflammatory responses.
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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00062K, Paper

Chaoli Xu, Ting Zhang, Guangming Lu, Kun Chen, Jun Tao, Yunlei Zhang, Zhaogang Teng, Bin Yang
Herein, we successfully constructed a combined therapeutic nanoplatform with high tumor targeting for cancer treatment by integrating gold nanorods with disulfiram (denoted Au-DSF). The Au-DSF integrates possess a uniform length...
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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00249F, Paper

Di Wu, zheng zhao, nan wang, xinrui zhang, honghong yan, xiaoqi chen, yunyun fan, weiwei liu, xuekui liu
Reliable diagnosed and efficient targeted therapy regime is important and may in turn lead to more effective laryngeal carcinoma treatments. Multifunctional nano-theranostic agents demonstrate great potential in tumor theranostic applications....
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00508H, Paper

Nitin D. Bansode, Kotagudda Ranganath Sindhu, Chloe Morel, Murielle Rémy, Julien Verget, Claudine Boiziau, Philippe Barthélémy
Constructing biocompatible soft materials via supramolecular approaches remains an important challenge for in vivo applications.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02012H, Paper

Boguang Yang, Fanglian Yao, Lei Ye, Tong Hao, Yabin Zhang, Lei Zhang, Dianyu Dong, Wancai Fang, Yan Wang, Xiaoyang Zhang, Changyong Wang, Junjie Li
The development of three-dimensional conductive scaffolds is vital to support the adhesion, proliferation and myocardial differentiation of stem cells in cardiac tissue engineering.
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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00370K, Paper

Maria Salem Ibrahim, Isadora Martini Garcia, Taissa Vila, Abdulrahman A. Balhaddad, Fabricio Mezzomo Collares, Michael D Weir, Huakun Xu, Mary Anne Melo
Dental caries in children is a leading worldwide concern for oral health. Combining antibacterial and remineralizing additives within dental sealants is a promising approach for caries prevention. Saliva contains oral...
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Biomater. Sci., 2020, 8,2404-2419
DOI: 10.1039/C9BM01904A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Y. Li, P. Pavanram, J. Zhou, K. Lietaert, F. S. L. Bobbert, Yusuke Kubo, M. A. Leeflang, H. Jahr, A. A. Zadpoor
First report on the effect of topology design on the biodegradation, mechanical properties, and cell responses of additively manufactured Zn.
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Biomater. Sci., 2020, 8,2447-2458
DOI: 10.1039/C9BM01889A, Paper

Yanqiu Wang, Xinyu Shen, Shang Ma, Qianqian Guo, Wei Zhang, Lu Cheng, Liming Ding, Zhuobin Xu, Jing Jiang, Lizeng Gao
Combining nanozymes and bacteria to eliminate dental biofilms in a mixed-species model.
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Biomater. Sci., 2020, 8,2481-2487
DOI: 10.1039/D0BM00021C, Paper

Zhen Ke, Aize Xie, Jianjiao Chen, Zhenyuan Zou, Lei Shen, Yansong Dai, Dengfeng Zou
Hypericin undergoing electron transfer can be used for type I PDT and PTT.
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Biomater. Sci., 2020, 8,2526-2536
DOI: 10.1039/C9BM02046B, Paper

Rui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan Wang
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
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Biomater. Sci., 2020, 8,2549-2563
DOI: 10.1039/C9BM01956A, Paper

Chungeng Liu, Weihua Qiao, Hong Cao, Jinchi Dai, Fei Li, Jiawei Shi, Nianguo Dong
Riboflavin–ultraviolet light A could effectively crosslink a decellularized heart valve to improve its biomechanical properties, stability and biocompatibility.
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Biomater. Sci., 2020, 8,2472-2480
DOI: 10.1039/D0BM00172D, Paper

Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.
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Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper

Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
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Biomater. Sci., 2020, 8,2590-2599
DOI: 10.1039/D0BM00314J, Paper

Julie Tzu-Wen Wang, Umberto Martino, Rehan Khan, Maasoomeh Bazzar, Paul Southern, Dönüş Tuncel, Khuloud T. Al-Jamal
Self-red-emitting magnetic PLGA-PEG nanocapsules for optical imaging and magnetic tumour targeting.
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Biomater. Sci., 2020, 8,2366-2375
DOI: 10.1039/C9BM02098E, Review Article

Jie Wu, Guanghui Ma
The design strategies of particle adjuvants by mimicking natural pathogens to strengthen their interaction with antigen-presenting cells.
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Biomater. Sci., 2020, 8,2507-2513
DOI: 10.1039/D0BM00078G, Paper

Rong Jin, Jing Sun, Liefu Zhou, Xuelian Guo, Aoneng Cao
Core-crosslinked dual-responsive micelles can be readily constructed from a pair of clickable copolymers and applied for controlled release of anticancer drugs in cancer therapy.
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Biomater. Sci., 2020, 8,2459-2471
DOI: 10.1039/D0BM00102C, Paper

Tian Ding, Jianhua Li, Xingshuang Zhang, Lingqian Du, Yang Li, Dengwang Li, Biao Kong, Shaohua Ge
In this work, a super-assembled framework (SAF) was fabricated to achieve sequential delivery of bFGF and BMP-2 for in situ cementum–ligament–bone complex regeneration.
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Biomater. Sci., 2020, 8,2488-2506
DOI: 10.1039/C9BM02081K, Paper

Hai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao Ran
A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.
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Biomater. Sci., 2020, 8,2420-2433
DOI: 10.1039/C9BM01905G, Paper

Vera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-Jamal
Cu(TPZ)₂ complex as a promising hypoxia selective cytotoxin in prostate cancer.
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Biomater. Sci., 2020, 8,2627-2637
DOI: 10.1039/D0BM00041H, Paper

Hwan D. Kim, Jungha Park, Sivashanmugam Amirthalingam, R. Jayakumar, Nathaniel S. Hwang
VEGF-overexpressing human tonsil-derived stem cells (VEGF-hTMSCs) and a whitlockite microenvironment induce vascularized bone tissue formation in biodegradable polymeric scaffolds.
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