Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer’s pathology  Nature.com

Plasma proteomic and polygenic profiling improve risk stratification and personalized screening for colorectal cancer  Nature.com

Highly sensitive site-specific SUMOylation proteomics in Arabidopsis  Nature.com

Proteomics identifies potential immunological drivers of postinfection brain atrophy and cognitive decline  Nature.com

Enhanced feature matching in single-cell proteomics characterizes IFN-γ response and co-existence of cell states  Nature.com

Plasma proteomics identify biomarkers predicting Parkinson’s disease up to 7 years before symptom onset  Nature.com

Multiplex cerebrospinal fluid proteomics identifies biomarkers for diagnosis and prediction of Alzheimer’s disease  Nature.com

Identifying proteomic risk factors for cancer using prospective and exome analyses of 1463 circulating proteins and risk of 19 cancers in the UK Biobank  Nature.com

Optimizing differential expression analysis for proteomics data via high-performing rules and ensemble inference  Nature.com

Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications  Nature.com

Spatial proteomics identifies JAKi as treatment for a lethal skin disease  Nature.com

Seer Showcases Deep Proteomics Capabilities, Announces Co-Marketing Deal with Thermo Fisher Scientific  Genetic Engineering & Biotechnology News

Extended Parking Lane Closures & Traffic Shifts at W. Lawrence Avenue between N. Broadway and N. Winthrop Avenue for Street Reconstruction & Final Asphalt.

Updated Dates & Impacts with Extended Parking Lane Closures & Traffic Shifts at W. Foster Avenue between N. Broadway and N. Winthrop Avenue for Street Reconstruction & Shoring Tower Construction & Staging.

W Argyle will have traffic lane shifts and a single-day closure to build new track strucutre over the street.

The Chicago Transit Authority (CTA) announced today the kickoff of a search for artists and/or artist teams interested in creating new, one-of-a-kind artwork for four locations throughout the system, as part of its continued expansion of public art to all CTA locations.

New Dates, Parking Lane Closure and Traffic Shifts at W. Foster Avenue between N. Broadway and N. Winthrop Avenue for Asphalt Placement

N Clifton will be closed to auto traffic between N Broadway and W Lawrence to allow crews to dissemble the construction gantry system.

Parking Lane Closure and Daily Lane Shift at W. Newport Avenue between N. Clark Street and 927 W. Newport Avenue for Asphalt Placement.

The post Fertility at work: Employers can make all the difference appeared first on Personnel Today.

The 40 hour work week has been the standard for 80 years. What will it take to lower that? | Subscribe to our weekly newsletter here.

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In 2016, thieves tried to steal nearly a billion dollars from the Bank of Bangladesh's reserves without ever entering the building. And six years later, justice hasn't been so SWIFT. | Subscribe to our weekly newsletter here.

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International trade is the web of cross-border relationships that binds economies together. Because of trade we have access to cheaper, higher-quality goods, and we get to benefit from other countries' cultures. Economics tells us trade makes society, overall on average, better off, but that doesn't mean everyone wins. Today, the good and bad of trade through the eyes of workers in developing economies who make the things sold around the world. We follow them as they navigate the ever-shifting international trade environment. |At this Summer School, phones ARE allowed during class... Check out this week's PM TikTok! | Listen to past seasons of Summer School here.

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Cold economic reasoning says, supposedly, that gifts are inefficient transfers of wealth. But Planet Money host Jeff Guo believes in the economic virtues of gift giving. On today's show, Jeff tries to win over Planet Money's resident Scrooge, Kenny Malone, by going on a quest to find him the perfect gift. Along the way, they're visited by the spirits of three Nobel prize-winning economic theories that can explain why gift-giving is actually good. And by the end, Kenny's heart may just grow three sizes larger. Subscribe to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney

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Welcome to the Planet Money Movie Club, a regular series from Planet Money+ in which we watch an economics-related movie and discuss! On today's episode, Kenny Malone, Wailin Wong, and Willa Rubin talk about Frank Capra's 1946 classic 'It's A Wonderful Life.' They discuss CPI adjustments, how a copyright lapse helped make the film more popular, and what exactly a 'Building and Loan' is.

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Right now, the economy is running hot. Inflation is high, and central banks are pushing up interest rates to fight it. But before the pandemic, economies around the world were stuck in a different rut: low inflation, low interest rates, low growth.

In 2013, Larry Summers unearthed an old term from the Great Depression to explain why the economy was in this rut: secular stagnation. The theory resonated with Olivier Blanchard, another leading scholar, because he had made similar observations himself. Larry and Olivier would go on to build a case for why secular stagnation was a defining theory of the economy and why government policies needed to respond to it. They helped reshape many people's understanding of the economy, and suggested that this period of slow growth and low interest rates was here to stay for a long time.

But today, Larry and Olivier are no longer the duo they used to be. As inflation has spiked worldwide, interest rates have followed suit. Earlier this year, Larry announced that he was no longer on the secular stagnation train. Olivier, meanwhile, believes we're just going through a minor blip and will return to a period of low interest rates within the near future. He doesn't see the deep forces that led to a long-run decline in interest rates as just vanishing. Who's right? The future of the global economy could depend on the answer.

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There's an estimated $195 billion of medical debt in America. But just because a medical bill comes in the mail doesn't mean you have to pay that exact price. In this special episode from our friends at Life Kit, you'll learn how to eliminate, reduce or negotiate a medical bill.

If you liked this episode, you can check out more Life Kit here. They have episodes on how to choose a bank, and how to save money at the grocery store.

This episode of Life Kit was produced by Sylvie Douglis. Their visuals editor is Beck Harlan, and their digital editor is Danielle Nett. Meghan Keane is their supervising editor, and Beth Donovan is their executive producer.

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Karen McDonough of Quincy, Mass., was enjoying her tea one morning in the dining room when she saw something odd outside her window: a group of people gathering on her lawn. A man with a clipboard told her that her home no longer belonged to her. It didn't matter that she'd been paying her mortgage for 17 years and was current on it. She was a nurse with a good job and had raised her kids there. But this was a foreclosure sale, and she was going to lose her house.

McDonough had fallen victim to what's called a zombie second mortgage. Homeowners think these loans are long dead. But then the loans come back to life because they get bought up, sometimes for pennies on the dollar, by debt collectors that then move to collect and foreclose on people's homes.

On today's episode: An NPR investigation reveals the practice to be widespread. Also, what are zombie mortgages? Is all this legal? And is there any way for homeowners to fight the zombies?

You can read more about zombie second mortgages online at: npr.org/zombie

Correction: An earlier version of this episode description misspelled Karen McDonough's last name as MacDonough.

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Graphite is sort of the one-hit wonder of minerals. And that hit? Pencils. Everyone loves to talk about pencils when it comes to graphite. If graphite were to perform a concert, they'd close out the show with "pencils," and everyone would clap and cheer. But true fans of graphite would be shouting out "batteries!" Because graphite is a key ingredient in another important thing that we all use in our everyday lives: lithium ion batteries.

Almost all of the battery-ready graphite in the world comes from one place: China. That's actually true of lots of the materials that go into batteries, like processed lithium and processed cobalt. Which is why it was such a big deal when, earlier this year, President Biden announced a tariff package that will make a bunch of Chinese imports more expensive. Included in this package are some tariffs on Chinese graphite. He wants to create a new battery future—one that doesn't rely so much on China.

In this episode, we get down on the ground to look at this big supply chain story through the lens of one critical mineral. And we visit a small town that realizes that it might be the perfect place to create an American graphite industry. And we find that declaring a new battery future is one thing, but making it happen is another thing entirely.

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Episodes each Wednesday through labor day. Find all the episodes from this season here. And past seasons here. And follow along on TikTok here for video Summer School.

Once upon a time, every business was a small business. It was run by the owner, maybe the spouse and the kids. Maybe they borrowed money from friends and relatives, but there was only so big it could get. Then came what can only be described as the big bang of economics. Over the span of a few decades, people figured out a way for businesses to sell ownership shares – otherwise known as stocks – and let people trade those shares. There was suddenly money to buy machines and expand.

Today, we head to the Netherlands around the year 1600. First, we'll visit the bridge in Amsterdam where some of the first stock trading took place. Then we track down the Dutch water company that's the source of the oldest "living" bond. It's the origin of stocks and bonds and the stock market and it leads directly to many of the financial innovations that we still have today.

This series is hosted by Robert Smith and produced by Audrey Dilling. Our project manager is Devin Mellor. This episode was edited by Planet Money Executive Producer Alex Goldmark and fact-checked by Sofia Shchukina.

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Take the 2024 Planet Money Summer School Quiz here to earn your personalized diploma!

Find all the episodes from this season of Summer School here. And past seasons here. And follow along on TikTok here for video Summer School.

We are assembled here on the lawn of Planet Money University for the greatest graduation in history – because it features the greatest economic minds in history. We'll hear from Adam Smith, Karl Marx, John Maynard Keynes, and some surprising guests as they teach us a little bit more economics, and offer a lot of life advice.

But first, we have to wrap up our (somewhat) complete economic history of the world. We'll catch up on the last fifty years or so of human achievement and ask ourselves, has economics made life better for us all?

This series is hosted by Robert Smith and produced by Audrey Dilling. Our project manager is Devin Mellor. This episode was edited by Planet Money Executive Producer Alex Goldmark and fact-checked by Sofia Shchukina.

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In the early 90s, teenagers LeAlan Jones and Lloyd Newman recorded a week of their lives on Chicago's South Side. Working with StoryCorps founder Dave Isay, LeAlan and Lloyd produced a documentary they called Ghetto Life 101, one of the most acclaimed programs in public radio history. In remembrance of Lloyd, who died this week, we bring you a special presentation of Ghetto Life 101.

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On this short Memorial Day episode, we'll hear from Marine Lance Cpl. Travis Williams, an Iraq War veteran who lost every other member of his 12-man squad.

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When a train ride to work veers into a life or death situation, two strangers become an important part of each other's lives.

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The Los Angeles-based musician was inspired by the dark side of state's mythology in the making of her fourth studio album.

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On The Past is Still Alive, folk songwriter Alynda Segarra reignites visions from a past life and the people they've met along the way.

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Find out which songs the English musician chose to perform for World Cafe's new feature called Backtracking.

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Right now, many kids aren't in their classrooms — but there is so much to learn outside of school as well. This hour, TED speakers explore life lessons that teach us far more than any textbook. Guests on the show include poltician Stacey Abrams, sailor Tracy Edwards, educator Alvin Irby, and LGBTQ rights advocate Ash Beckham.

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Cities are never static; they can transform in months, years, or centuries. This hour, TED speakers explore how today's cities are informed by the past, and how they'll need to evolve for the future. Guests include archaeologist Alyssa Loorya, architects Marwa Al-Sabouni and Rahul Mehrotra, and landscape architect Kotchakorn Voraakhom.

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Original broadcast date: October 20, 2020. Right now, many kids aren't in their classrooms — but there is so much to learn outside of school as well. This hour, TED speakers explore life lessons that teach us far more than any textbook. Guests on the show include politician Stacey Abrams, sailor Tracy Edwards, educator Alvin Irby, and LGBTQ rights advocate Ash Beckham

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In each stage of life, our brains morph and change. This hour, TED speakers explore pivotal chapters where the brain can either flourish or decline – and what control we might have over brain health. Guests include neuroscientists Kimberly Noble, Adriana Galván, Sandrine Thuret, and Lisa Mosconi.

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Original broadcast date: November 13, 2020. Cities are never static; they can transform in months, years, or centuries. This hour, TED speakers explore how today's cities are informed by the past, and how they'll need to evolve for the future. Guests include archaeologist Alyssa Loorya, architects Marwa Al-Sabouni and Rahul Mehrotra, and landscape architect Kotchakorn Voraakhom.

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When experiencing grief or hardship, how can we move forward? This hour, writer Nora McInerny shares ideas on navigating the most difficult parts of life ... and living life fully in the face of loss.

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Original broadcast date: October 2, 2020. Millions of kids returned to school this month. But if there's one thing we've learned from the past two years, it's that there's so much to learn outside the classroom as well. This hour, TED speakers explore life lessons that teach us far more than any textbook. Guests on the show include politician Stacey Abrams, sailor Tracy Edwards, educator Alvin Irby, and LGBTQ rights advocate Ash Beckham.

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Original broadcast date: March 5, 2021. In each stage of life, our brains morph and change. This hour, TED speakers explore pivotal chapters where the brain can either flourish or decline – and what control we might have over brain health. Guests include neuroscientists Kimberly Noble, Adriana Galván, Sandrine Thuret, and Lisa Mosconi.

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When experiencing grief or hardship, how can we move forward? This hour, writer Nora McInerny shares ideas on navigating the most difficult parts of life... and living life fully in the face of loss.

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Original broadcast date: November 15, 2020. Cities are never static; they can transform in months, years, or centuries. This hour, TED speakers explore how today's cities are informed by the past, and how they'll need to evolve for the future. Guests include archaeologist Alyssa Loorya, architects Marwa Al-Sabouni and Rahul Mehrotra, and landscape architect Kotchakorn Voraakhom.

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Are we alone in the universe? Are we one of a crowd? This hour, we travel the cosmos with TED science curator David Biello, exploring where we are in the search for alien life.

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Original broadcast date: March 5, 2021. In each stage of life, our brains morph and change. This hour, TED speakers explore pivotal chapters where the brain can either flourish or decline – and what control we might have over brain health. Guests include neuroscientists Kimberly Noble, Adriana Galván, Sandrine Thuret, and Lisa Mosconi.

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Original broadcast date: March 5, 2021. In each stage of life, our brains morph and change. This hour, TED speakers explore pivotal chapters where the brain can either flourish or decline – and what control we might have over brain health. Guests include neuroscientists Kimberly Noble, Adriana Galván, Sandrine Thuret, and Lisa Mosconi.

TED Radio Hour+ subscribers now get access to bonus episodes, with more ideas from TED speakers and a behind the scenes look with our producers. A Plus subscription also lets you listen to regular episodes (like this one!) without sponsors. Sign-up at: plus.npr.org/ted

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