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Pronounced Electronic Modulation of Geometrically-Regulated Metalloenediyne Cyclization

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05396F, Edge Article
Open Access
Sarah E. Lindahl, Erin M. Metzger, Chun-Hsing Chen, Maren Pink, Jeff Zaleski
Using a diverse array of thermally robust phosphine enediyne ligands (dxpeb, X = Ph, Ph-pOCH3, Ph-pCF3, Ph-m2CH3, Ph-m2CF3, iPr, Cy, and tBu) a novel suite of cisplatin-like Pt(II) metalloenediynes (3,...
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Discovery of penicillic acid as a chemical probe against tau aggregation in Alzheimer’s Disease

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05469E, Edge Article
Open Access
Jennifer Shyong, Jinliang Wang, Tran Quoc Dung Huynh, Marina Fayzullina, Bo Yuan, Ching-Kuo Lee, Thomas Minehan, Paul M. Seidler, Clay Wang
Alzheimer’s Disease (AD) is a neurodegenerative disorder proven to be caused by the aggregation of protein tau into fibrils, resulting in neuronal death. The irreparable neuronal damage leads to irreversible...
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Sequence-dependent Conformational Transitions of Disordered Proteins During Condensation

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05004E, Edge Article
Open Access
Jiahui Wang, Dinesh Devarajan, Keerthivasan Muthukumar, Youngchan Kim, Arash Nikoubashman, Jeetain Mittal
Intrinsically disordered proteins (IDPs) can form biomolecular condensates through phase separation. It is recognized that the conformation of IDPs in the dense and dilute phases, as well as at the...
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Spin State Modulation and Kinetic Control of Thermal Contraction in a [Fe2Co2] Discrete Prussian Blue Analogue

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05792A, Edge Article
Open Access
Jyoti Yadav, Sanjit Konar
Stimuli-responsive switchable molecules represent an important category of magnetic materials with significant potential for functional devices. However, engineering complexes with controlled switchability remains challenging due to their sensitivity to lattice...
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Standing apart: Shivam Pradhan




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Warrior prince and talking heads

The playfulness to the writing around Ravana and his ten perennially bickering heads could have made the film oddly amusing. But alas, the humour remains just a flash




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Progressive forces to unite at Goa meet




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In praise of playful banter

Manav Kaul writes, directs and acts opposite Sugandha Garg in a theatrical production about two small towners who might be in love




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In a Judas Priest state of mind

Kryptos describe their new album as traditional heavy metal laced with a bit of psychedelic rock




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Share Market Highlights 18 April 2024: Sensex falls 330 pts, Nifty at 22,000; media, metal stocks shine, FMCG, healthcare drag

Sensex, Nifty updates on 18th April 2024: Equity benchmarks BSE Sensex and NSE Nifty extended losses on Thursday. As per provisional figures, BSE Sensex fell 332.23 pts or 0.46 per cent to trade at 72,611.45 as of 3.35 pm and Nifty 50 declined 103.70 pts or 0.47 per cent to trade at 22,044.20., Bharti Airtel, Power Grid Corp, M&M, BPCL, and Tata Steel were the top gainers, while Nestle, Apollo Hospitals, Axis Bank, HCL Technologies, and ONGC were the major laggards. The stocks that hit a 52-week high on the NSE include AAA Tech (19.33 per cent), Just Dial (12.95 per cent), Indo Tech (10 per cent) and Hi-Tech Gear (10 per cent).




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Should you invest in ICICI Prudential Credit Risk Fund?

Credit risk funds, which invest at least 65 per cent of their portfolio in corporate bonds rated AA or below, offer a shot at high accrual returns




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North prefers equity, South less of it, East and West a mix

Pan-India, the diversity ties in with the fact that B30 cities are aggressive on equity compared to T30




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Prudent crosses ₹1 lakh crore in MF Assets Under Management

Prudent became the second non-banking mutual fund distributor to achieve this milestone last Friday




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ICICI Prudential Flexicap Fund: A steady outperformer for the long term

ICICI Prudential Flexicap’s performance over the past three years places it in the top-quartile of its category




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ICICI Pru Equity & Debt Fund review: A slight tilt to safety

Broad portfolio of holdings in equity and debt to limit portfolio downside during corrections from the peaks




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PM Modi a 'demanding' boss, have to be 'fully prepared' to hold discussions with him: EAM Jaishankar




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'Namo buddhaya': Kiren Rijiju expresses gratitude on visit to Buddha memorial in Maharashtra's Nashik




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Global leader PM Modi deserves Nobel Peace prize: Ace investor Mark Mobius




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President Obama Election 2008 Named Best Seller

The New York Times Book Review of January 18, 2009 features President Obama Election 2008: A Collection of Newspaper Front Pages Selected by the Poynter Institute at #28 on the Paperback NonFiction Best Seller List

The election of Barack Obama as the first African-American president of the United States was a worldwide historic event resulting in perhaps some of the most important front pages in US history. President Obama Election 2008 is a collection of over seventy November 5th, 2008 newspaper front pages from around the world. There is no better statement of the emotion, excitement, and significance of this moment in history.

During his campaign for the White House, Barack Obama garnered an almost frenzied following. President Obama Election 2008 will be a cherished keepsake or gift for any of the millions of Americans who cast their vote for the 44th President of the United States. Here is the must-have commemorative book on this historic event.

  • Features over 70 historic newspaper front-pages from the day after the election, including international, campus, and ethnic publications.
  • Includes an introduction by Doonesbury creator Garry Trudeau.
  • Compiled by The Poynter Institute, a non-profit, non-partisan school of journalism.

About The Poynter Institute

Founded in 1975, The Poynter Institute is a school dedicated to teaching and inspiring journalists and media leaders. It promotes excellence and integrity in the practice of craft and in the practical leadership of successful businesses. It stands for a journalism that informs citizens and enlightens public discourse. It carries forward Nelson Poynter's belief in the value of independent journalism in the public interest. As a financially independent, nonprofit organization, The Poynter Institute is beholden to no interest except its own mission: to help journalists seek and achieve excellence.

To purchase: http://www.andrewsmcmeel.com/products/?isbn=0740784803



  • President Obama Election 2008
  • The New York Times Book Review
  • The Poynter Institute

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President Obama Reviewed by Philadephia Inquirer

The Philadelphia Inquirer’s review of President Obama Election 2008: A Collection of Newspaper Front Pages Selected by the Poynter Institute on Sunday (1/19/09) includes the following:

Everyone should probably grab one as a momento, but for sheer fun, the best of the commemoratives is President Obama/Election 2008: A Collection of Newspaper Front Pages from the Poynter Institute (Andrews McMeel). It gathers dull headlines (“Historic Victory”), witty ones (the Tulsa World’s, “Yes He Did”), and lovingly local riffs (The Jakarta Post’s “Barry’s Done It!”).


President Obama
(ISBN-13: 978-0-7407-8480-4)




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Placental microphysiological systems: new advances on promising platforms that mimic the microenvironment of the human placenta

Lab Chip, 2025, Advance Article
DOI: 10.1039/D4LC00500G, Critical Review
Inês M. Gonçalves, Muhammad Afzal, Nithil Kennedy, Ana Moita, Rui Lima, Serge Ostrovidov, Takeshi Hori, Yuji Nashimoto, Hirokazu Kaji
This review presents new advancements in placental MPS models for toxicological screening, preeclampsia assessment, and embryo uterine implantation and an overview of bioprinting technology and current advances in endometrial MPSs.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Rapid miRNA detection in skin interstitial fluid using a hydrogel microneedle patch integrated with DNA probes and graphene oxide

Lab Chip, 2024, 24,4989-4997
DOI: 10.1039/D4LC00715H, Paper
Hanjia Zheng, Fatemeh Keyvani, Sadegh Sadeghzadeh, Dragos F. Mantaila, Fasih A. Rahman, Joe Quadrilatero, Mahla Poudineh
A simple and rapid fluorescence-based sensor sensors using DNA functionalized graphene oxide for miRNA detection from skin interstitial fluid.
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Compact lens-free imager using a thin-film transistor for long-term quantitative monitoring of stem cell culture and cardiomyocyte production

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00528G, Paper
Open Access
Taishi Kakizuka, Tohru Natsume, Takeharu Nagai
A novel compact lens-free imager achieved high-throughput long-term monitoring within an incubator, demonstrating the quantification of the confluency of human iPS cells, epithelial-to-mesenchymal transition, and cardiomyocyte beating dynamics.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A microfluidic hanging droplet as a programmable platform for mammalian egg vitrification

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00428K, Paper
Open Access
Haidong Feng, Georgios Katsikis, India D. Napier, Gong Du, Josh Lim, Joseph O. Doyle, Scott R. Manalis, Linda G. Griffith
Programmable microfluidic hanging drop system for motorized, contactless cryoprotectant loading and egg vitrification.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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3D-printed microfluidic–microwave device for droplet network formation and characterisation

Lab Chip, 2024, 24,5101-5112
DOI: 10.1039/D4LC00387J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kai Silver, Jin Li, Adrian Porch, William David Jamieson, Oliver Castell, Pantelitsa Dimitriou, Colin Kallnik, David Barrow
A 3D-printed microwave–microfluidic device using a liquid metal resonator for droplet network formation and characterisation.
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Effect of base methylation on binding and mobility of bacterial protein Hfq on double-stranded DNA

Lab Chip, 2024, 24,5137-5144
DOI: 10.1039/D4LC00628C, Paper
Jijo Easo George, Rajib Basak, Indresh Yadav, Chuan Jie Tan, Jeroen A. van Kan, Frank Wien, Véronique Arluison, Johan R. C. van der Maarel
Using nanofluidics to probe protein mobility on DNA reveals how DNA base methylation impacts protein–DNA interactions.
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An imaging scheme to study the flow dynamics of co-flow regimes in microfluidics: implications for nanoprecipitation

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00652F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Wali Inam, Anton Vladyka, Joanna W. Pylvänäinen, Junel Solis, Dado Tokic, Pasi Kankaanpää, Hongbo Zhang
Herein, by presenting a novel imaging-based scheme for analyzing fluid interactions in co-flow regimes, we identify oscillatory and chaotic flow behaviors to optimize nanoprecipitation through controlled fluid manipulation.
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RTO to probe operator’s failure to provide accommodation to students




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Hema Committee report: Preliminary inquiry in cases to be completed by December-end, Kerala govt tells HC

Submission made in a progress report filed by Kerala govt in response to public interest litigation in High Court filed in connection with Hema Committee report




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CKCL, private players help fill gaps in non-biodegradable waste management in Ernakulam




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Syro-Malabar Church affirms solidarity with Munambam protesters

State government must urgently intervene in the issue, since hundreds of families are facing threat of displacement from the land they had purchased and had been staying in for decades, says Church spokesperson




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Hurdles abound for SilverLine as Railways seek revised DPR for project




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Not afraid of any probe, says Mamkootathil




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Seaplanes have potential to woo high-budget tourists to Kerala: Biju Prabhakar

Aviation Secretary says these amphibious aircraft can link tourism locales in the State. A seaplane will operate a trial service from Kochi International Marina to the Mattupetty dam in Munnar on Monday




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CM owes Oommen Chandy an apology for sabotaging seaplane project: Sudhakaran 




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Centre, State must intervene in Munambam Waqf property issue, says Thattil




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HC allows medical termination of pregnancy of minor rape survivor

Division Bench passed the order while allowing an appeal filed against a single judge’s order declining permission. Medical board said that termination of pregnancy was most appropriate




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Catholic Church to intensify Munambam protests

Protest gatherings were held in over 1,500 parishes of the Syro-Malabar Church across the State




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HC asks Wayanad DLSA to formulate action plan to prevent child marriages among tribal communities




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HC tells authorities to prevent anti-social activities by other methods before resorting to KAAPA




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Detailed probe launched into fire at commercial unit near Aluva




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Pre-paid taxi counters for Sabarimala pilgrims: HC seeks Railways response




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Kerala HC quashes criminal case against former postal officials for taking possession of Waqf property

The post office was functioning from 1999, even before the insertion of section 52A in Waqf Act, which makes purchase or possession of Waqf property without Waqf Board nod punishable




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Migrant's progress



  • R K Nair

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Primitive blame game

The latest controversy gives rise to a nagging suspicion: Were the utterances of the Kerala Chief Minister and his Cabinet colleague aimed at deflecting attention from the raging solar scam?



  • R K Nair

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Isnt She Beautiful for the Mysore Dasara Sprint Championship




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Mescalito impresses




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Tom Cruiser wins Mysore Dasara Sprint Championship-2024




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Mojito and Waikiki impress




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Rains curtails Thursday’s race programme