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Development of a Xanthene-Based NIR Fluorescent Probe for Accurate and Sensitive Detection of γ-Glutamyl Transpeptidase in Cancer Diagnosis and Treatment

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01841A, Paper
Chia-Kai Lai, KUPPAN MAGESH, Sivan Velmathi, Shu-Pao Wu
γ-Glutamyl transpeptidase (GGT) regulates glutathione (GSH), essential for cell functions and linked to cancer. High GGT levels in tumors make it a valuable cancer biomarker. Current GGT detection methods often...
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Quantum DFT analysis and molecular docking investigation of various potential breast cancer drugs

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01803F, Paper
Ashraf Ayub, Ankit Raj Tyagi, Sunil Kumar Srivastava, Pranveer Singh
Breast cancer is the most often diagnosed and deadliest type of cancer in the world. These days, the world is facing the threat of breast cancer. It is essential to...
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Cuproptosis in cancer therapy: mechanisms, therapeutic application and future prospects

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01877J, Review Article
Jiawei Hu, Junfei Zhu, Tao Chen, Yudie Zhao, Qingwen Xu, Yan Wang
Cuproptosis is a regulated form of cell death induced by the accumulation of metal ions and is closely linked to aspects of cellular drug resistance, cellular metabolism, and signalling pathways.
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Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01883D, Review Article
Liyue Wen, Min Wang
Design and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.
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Fluorescence sensing techniques for quality evaluation of traditional Chinese medicines: a review

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01886A, Review Article
Yanyu Xiao, Hui Wang, Chenxia Gao, Xinyi Ye, Yuting Lai, Meiling Chen, Xiaoliang Ren
We summarized the advantages and advanced applications of fluorescence sensing technology compared with other analytical techniques, as well as the challenges and prospects of current application in the field of TCM quality evaluation.
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Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
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Illuminating cisplatin-induced ferroptosis in non-small-cell lung cancer with biothiol-activatable fluorescent/photoacoustic bimodal probes

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Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01656D, Paper
Li Xu, Hongwen Liu, Yi Kong, Lingyun Li, Jia Li, Kang Li, Shuzhi Liang, Bolin Chen
Using activatable NIR fluorescent/PA bimodal probes, we successfully monitored real-time biothiol changes during ferroptosis in NSCLC cells and tumors, revealing enhanced ferroptosis with the combined use of erastin and cisplatin.
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Bimetallic doped carbon dot nanozymes for enhanced sonodynamic and nanocatalytic therapy

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J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01916D, Paper
Yandong Huang, Lanting Jia, Shiqi Zhang, Lan Yan, Lei Li
The conventional inorganic semiconductors are not suitable for acting as nanozymes or sonosensitizers for in vivo therapeutic nanomedicine owing to the lack of excellent biocompatibility. Biocompatible carbon dots (CDs) exhibit...
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Recent Advances in Polymer-based Thin-film Electrode for ECoG Applications

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J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB02090A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Zhengchen Xiang, Liangtao Yang, Bin Yu, Qi Zeng, Tao Huang, Shuo Shi, Hao Yu, Yi Zhang, Jinglong Wu, Meifang Zhu
Electrocorticography (ECoG) has garnered widespread attention due to its superior signal resolution compared to conventional electroencephalogram (EEG). While ECoG signal acquisition entails invasiveness, the invasive rigid electrode inevitably inflicts damage...
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Dual-functional PCN-242 (Fe2Co) MOF for sensitive bacterial endotoxin detection

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01944J, Paper
Sivasankar Kulandaivel, Yung-Kang Lu, Chia-Her Lin, Yi-Chun Yeh
This work introduces a novel bimetallic MOF with superior endotoxin detection and enhanced catalytic activity for broader diagnostic applications.
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NIR emissive probe for fluorescence turn-on based dead cell sorting and in vivo viscosity mapping in C. elegans

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Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01945H, Paper
Goraksha T. Sapkal, Farhan Anjum, Abdul Salam, Bodhidipra Mukherjee, Shilpa Chandra, Purabi Bala, Richa Garg, Shagun Sharma, Kush Kaushik, Chayan Kanti Nandi
An NIR emissive probe plays a pivotal role for in vitro and in vivo dead cell sorting.
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Princess Devsena, now on television

By www.rediff.com
Published On :: Wed, 07 Jun 2017 08:27:48 +0530

Coming up: Aarambh: 'Biggest Indian TV show ever'


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Masks. PPE. No Romance. The New Normal at Telly Shoots

By www.rediff.com
Published On :: Wed, 08 Jul 2020 12:53:01 +0530

'We have fewer actors in every scene.''We don't have family scenes or scenes that involve a lot of people.''We are not doing scenes which are intimate or require closeness.'


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'Can you imagine dancing with Madhuri Dixit?'

By www.rediff.com
Published On :: Tue, 09 Aug 2022 14:45:32 +0530

Madhuri Dixit, Karan Johar and Nora Fatehi will judge Jhalak Dikhhla Jaa.


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Jhalak's GLAMOROUS Stars Are Ready To Dance!

By www.rediff.com
Published On :: Thu, 25 Aug 2022 15:40:00 +0530

If these celeb sightings are anything to go by, the 10th edition of Jhalak Dikhhla Jaa is going to be a visual delight.


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Bigg Boss 16: Shalin-Nimrat Fight For Captaincy

By www.rediff.com
Published On :: Fri, 07 Oct 2022 12:14:13 +0530

While Nimrat Kaur Ahluwalia retains her captaincy, Gori Nagori wins the entertainment task.


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'Once you do TV, you won't get films'

By www.rediff.com
Published On :: Mon, 01 May 2023 12:59:01 +0530

'You found me eligible and you think I am the perfect cast, then why don't you give me work?''That used to happen only because I have done TV.'


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Nurturing entrepreneurial instincts

By www.thehindu.com
Published On :: Sun, 06 Nov 2016 17:00:50 +0530

How can institutions become eligible for receiving support from the Government of India for setting up technology business incubators?


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A transformative experience

By www.thehindu.com
Published On :: Sun, 13 Nov 2016 17:00:34 +0530

PARAS ARORA’S internship at Teach for India helped him become an activist.


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At K Sureshkumar’s pedagogical laboratory in Thiruvananthapuram students understand basic concepts of Physics by doing experiments on their own

By www.thehindu.com
Published On :: Fri, 07 Oct 2022 14:23:10 +0530

National award-winning science teacher K Sureshkumar’s pedagogical laboratory in Thiruvananthapuram enables students of high school to conduct experiments in Physics and learn the concepts themselves


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Prince Philip on how to ‘get on with it’

By www.thehindubusinessline.com
Published On :: Sun, 25 Jul 2021 08:57:27 +0530

Gyles Brandreth’s biography is an anecdote-filled final portrait of the ever-practical duke


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Loki throws the timelines of the worlds out of sync

By www.thehindubusinessline.com
Published On :: Tue, 27 Jul 2021 10:36:39 +0530

In the latest offering from Marvel Cinematic Universe, Loki goes in search of a variant — one creating nexus events


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Breaking the toxic chain of pretence

By www.thehindubusinessline.com
Published On :: Tue, 10 Aug 2021 13:10:25 +0530

A mother, wife, daughter, friend and a colleague shares her struggle to stop pretending that she is in control and accept that it is okay not to be okay


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Beyonce expecting twins; Twitter explodes!

By www.rediff.com
Published On :: Thu, 02 Feb 2017 14:03:24 +0530

Queen Bey and her rapper husband Jay Z are already parents to daughter Blue Ivy.


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PIX: Beyonce, Adele, Lady Gaga at the Grammys

By www.rediff.com
Published On :: Mon, 13 Feb 2017 13:17:53 +0530

The 59th Grammy Awards was held in Los Angeles, California.


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Oscar Nominations: A Quick Glance

By www.rediff.com
Published On :: Tue, 23 Jan 2024 20:30:10 +0530

The nominations for the 96th annual Academy Awards have been announced.


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Surface-enhanced Raman scattering enhancement using a hybrid gold nanoparticles@carbon nanodot substrate for herbicide detection

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5277-5286
DOI: 10.1039/D4AN00649F, Paper
Open Access
Naghmeh Aboualigaledari, Anitha Jayapalan, Panesun Tukur, Mengxin Liu, Frank Tukur, Yanling Zhang, Gerald Ducatte, Madan Verma, Janet Tarus, Simona E. Hunyadi Murph, Jianjun Wei
Hybrid nanoparticles composed of gold nanoparticles and carbon nanodots provide great signal amplification in SERS detection of herbicide molecules.
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A cerium-doped tungsten trioxide-functionalized sensing platform for photoelectrochemical detection of ascorbic acid with high sensitivity

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5206-5212
DOI: 10.1039/D4AN01165A, Paper
Xueying Zhu, Tikai Liang, Dianping Tang
A highly efficient photoelectrochemical (PEC) strategy was proposed for the determination of ascorbic acid (AA).
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An ultra-sensitive ammonia sensor based on a quartz crystal microbalance using nanofibers overlaid with carboxylic group-functionalized MWCNTs

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5191-5205
DOI: 10.1039/D4AN01061B, Paper
Ahmad Hasan As'ari, Rizky Aflaha, Laila Katriani, Ahmad Kusumaatmaja, Iman Santoso, Rike Yudianti, Kuwat Triyana
Utilizing the specific interaction between carboxylic groups and ammonia gas has led to the development of an ultra-sensitive ammonia sensor based on a quartz crystal microbalance using nanofibers overlaid with carboxylic group-functionalized MWCNTs.
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Reference-free quantitative mass spectrometry in the presence of nonlinear distortion caused by in situ chemical reactions among constituents

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Published On ::

Analyst, 2024, 149,5320-5328
DOI: 10.1039/D4AN00961D, Paper
Yusuke Hibi
Nonlinear reference-free analysis in pyrolysis-MS enables accurate compositional analysis even in reactive and interactive systems.
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Utilizing solid-state nanopore sensing for high-efficiency and precise targeted localization in antiviral drug development

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5313-5319
DOI: 10.1039/D4AN00946K, Paper
Wei Xu, Lichun Zou, Haiyan Wang, Changhui Xu, Qinyang Fan, Jingjie Sha
The efficient identification and validation of drug targets are paramount in drug discovery and development.
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A sulphide resistant Ag|AgCl reference electrode for long-term monitoring

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Published On ::

Analyst, 2024, 149,5225-5231
DOI: 10.1039/D4AN01076K, Paper
Open Access
David S. Macedo, Mikko Vepsäläinen, Theo Rodopoulos, Stephen Peacock, Conor F. Hogan
Solid state reference electrodes (SSREs) with suspended AgCl are resistant to sulphide poisoning. Sulphide species are precipitated as Ag2S, inhibiting their diffusion through the polymer composite.
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Alterations of the chemical profile of cholesterol in cancer tissue as traced with ToF-SIMS

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Published On ::

Analyst, 2024, 149,5344-5352
DOI: 10.1039/D4AN01050G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Auraya Manaprasertsak, Julhash U. Kazi, Catharina Hagerling, Kenneth J. Pienta, Per Malmberg, Emma U. Hammarlund
This study uses Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) to analyze cholesterol alterations in cancer tissue, revealing changes in fragmentation and isotopes that suggest potential diagnostic vulnerabilities.
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A highly sensitive and reproducible fluorescence sensor for continuously measuring hydrogen peroxide at the sub-ppm level

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5353-5359
DOI: 10.1039/D4AN00975D, Paper
Yang Yang, Rui Jiang, En-lai Yang, Jiahao Liang, Ying Xu, Xu-dong Wang
Highly sensitive and reversible fluorescence H2O2 sensor with a limit of detection of 0.02 ppm had been developed. The sensor responded rather fast, had high stability, and can be massively produced with good batch-to-batch consistency.
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Surface-enhanced Raman spectroscopy with single cell manipulation by microfluidic dielectrophoresis

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Published On ::

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00983E, Paper
Kwanhwi Ko, Hajun Yoo, Sangheon Han, Won Seok Chang, Donghyun Kim
The combination of dielectrophoresis and surface-enhanced Raman spectroscopy provides an effective method for analyzing the Raman characteristics and the dielectrophoretic behavior of polystyrene beads and U-87MG cells in a microfluidic environment.
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In situ study of the interactions between metal surfaces and cationic surfactant corrosion inhibitors by surface-enhanced Raman spectroscopy coupled with visible spectroscopy

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5372-5380
DOI: 10.1039/D4AN00861H, Paper
Open Access
Felix Frank, Daniela Tomasetig, Peter Nahringbauer, Wolfgang Ipsmiller, Gerd Mauschitz, Karin Wieland, Bernhard Lendl
Coupling Raman and VIS spectroscopy enables the study of AgNP aggregations induced by surfactants.
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Advancing triage of acute lymphoblastic leukaemia subtypes diagnosis: label-free Raman spectroscopy for precise single-cell phenotyping and subtype classification

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5443-5454
DOI: 10.1039/D4AN00956H, Paper
Patrycja Leszczenko, Anna M. Nowakowska, Patrycja Dawiec, Karolina Czuja, Justyna Jakubowska, Marta Zabczynska, Agata Pastorczak, Kinga Ostrowska, Szymon Tott, Wojciech Mlynarski, Malgorzata Baranska, Katarzyna Majzner
Acute lymphoblastic leukaemia (ALL) is a complex disease in pediatric oncology, necessitating accurate diagnostic strategies for effective treatment planning.
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Advancing cerumen analysis: exploring innovative vibrational spectroscopy techniques with respect to their potential as new point-of-care diagnostic tools

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5381-5393
DOI: 10.1039/D4AN00868E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Edoardo Farnesi, Matteo Calvarese, Chen Liu, Carl Messerschmidt, MohammadSadegh Vafaeinezhad, Tobias Meyer-Zedler, Dana Cialla-May, Christoph Krafft, Jonas Ballmaier, Orlando Guntinas-Lichius, Michael Schmitt, Jürgen Popp
The study demonstrates the potential of advanced vibrational spectroscopy to reveal the complex molecular composition of cerumen, suggesting its promising application as a non-invasive diagnostic tool for identifying disease-related biomarkers.
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A nano-biosensing platform based on CuS-BSA for label-free fluorescence detection of Escherichia coli

By pubs.rsc.org
Published On ::

Analyst, 2024, 149,5394-5400
DOI: 10.1039/D4AN01060D, Paper
Xiaoqing Zhang, Shanglin Li, Mei Liu
A fluorescence biosensing strategy was developed based on CuS-BSA for sensitive and rapid detection of Escherichia coli.
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A gold nanomaterial-integrated distance-based analytical device for uric acid quantification in human urine samples

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Published On ::

Analyst, 2024, 149,5518-5526
DOI: 10.1039/D4AN01139B, Paper
Tapparath Leelasattarathkul, Thithawat Trakoolwilaiwan, Kawin Khachornsakkul
A simple and low-cost distance-based paper analytical device (dPAD) was combined with gold nanomaterials for uric acid quantification.
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An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and a one-dimensional neural network combining ResNet and SENet

By pubs.rsc.org
Published On ::

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00784K, Paper
Liang Ma, Wenqing Gao, Xiangyang Hu, Dongdong Zhou, Chenlu Wang, Jiancheng Yu, Keqi Tang
An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and 1D neural network combining ResNet and SENet is proposed and successfully applied to the diagnosis of ovarian cancer with high accuracy and strong fitting ability.
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Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry

By pubs.rsc.org
Published On ::

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01260G, Paper
Sunil S. Adav, Yan Wen Crystal Tan, Choon Teck Low, Song Wei Loo, Ridhwan Yusoff, Archana Gautam, Yuk Lin Yong, Chiew Yung Yang, Chin Chin Lim, Kee Woei Ng
In firearm forensic investigations, detecting gunshot residue (GSR) is crucial for linking firearms to suspects and determining firing distance for forensic reconstruction.
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