TRB’s Airport Cooperative Research Program (ACRP) Synthesis 34: Subsurface Utility Engineering Information for Airports examines ways in which information on subsurface utilities is collected, maintained, and used by airports, their consultants, and the U.S. Federal Aviation Administration to help increase the effectiveness of, and enhance safety during, infrastructure development programs at airports. The report also compares the current state of technology and effective processes from other industry se...

EPA announced the availability of the Guidelines for Human Exposure Assessment (hereafter "Guidelines"). The Guidelines present the current policies and practices of exposure assessors across the Agency and supersede the 1992 Guidelines for Exposure Assessment Edition.

The September 2015 issue of TRB’s Airport Cooperative Research Program (ACRP) Impacts on Practice explores how Philadelphia International Airport, Fort Lauderdale-Hollywood International Airport, and Changi Airport in Singapore applied guidance from ACRP Report 52 : Wayfinding and Signing Guidelines for Airport Terminals and Landside to help passengers find their way in and around an airport.

The University of Texas at Austin is hosting Bridging Transportation Researchers (BTR) Online Conference  on August 11-12, 2020. TRB is pleased to cosponsor this event. This zero-carbon, zero-cost conference will host multiple Zoom-based tracks to virtually and globally unite transportation engineers, planners, and policymakers to discuss a wide range of transportation research topics and results, including: Multi-modal transportation network and systems Travel demand forecasting, including connecte...

The March-April 2020 issue of TR News (#326) - including a cover feature on TRB's "century of progress and foundation for the future" of transportation research - is available in hard copy and digital copy for subscribers. For those who are not subscribers, the table of contents is available. Other feature articles in the issue include ones on whether research processes can keep up, accessible rail sleeper compartments, drones and lasers for railroad bridges, implications of California wildfires, and muc...

Česko se zastavilo. Vláda kvůli pandemii koronaviru zavedla nouzový stav, který má šířené nemoci zamezit. Jaký je život v nouzovém režimu? Jak se chovají lidé, jak reaguje ekonomika? Hrozí, že vláda současné krize zneužije ke šmírování a omezení práva i po skončení pandemie? V online komentovaném přenosu vážně ale i s nadsázkou odpovidají redaktoři a spolupracovníci Reflexu.

M0rphine ransomware removal instructions

What is M0rphine?

Similar to SatanCryptor ransomware, M0rphine is a malicious program. Credit for its discovery belongs to dnwls0719. Systems infected with this ransomware experience data encryption and receive ransom demands for the decryption tools/software. During the encryption process, all affected files are retitled according to this pattern: original filename, unique ID assigned to the victims, cyber criminals' email address and the ".M0rphine" extension. For example, a file like "1.jpg" would appear as something similar to "1.jpg. [ID-764E0CF4DF4828D6303F40B19514805A] -[EMAIL-M0rphine@cock.li].M0rphine" - following encryption. After this process is complete, a ransom note - "# M0rphine Help #.hta" is dropped into every compromised folder.

Cosappzsearch.online redirect removal instructions

What is cosappzsearch.online?

Cosappzsearch.online is a useless, fake search engine. As a rule, such search engines are promoted through potentially unwanted applications (PUAs), browser hijackers. Apps of this type promote fake search engines by changing certain browser's settings. It is common that they gather browsing data and/or other information as well. Quite often users download and install potentially unwanted apps unknowingly, accidentally.

Ossearch.online redirect removal instructions

What is ossearch.online?

Ossearch.online is one of the many fake search engines that do not generate individual results. As a rule, their addresses are promoted through potentially unwanted applications (PUAs) that are classified as browser hijackers. In most cases apps of this type are designed to promote some fake search engine by changing browser's settings and collect browsing-related (and/or other) information. Browser hijackers are categorized as PUAs because users often download and install them inadvertently.

Kelly Loeffler is, by far, the wealthiest elected official in Congress, with an estimated net worth of half a billion dollars (the second wealthiest is Montana Rep. Greg Gianforte (famous for his body slamming a journalist for asking him a question and then lying to the police about it)). Loeffler may be used to getting away with tearing up the red tape in her previous life, but in Congress, that often looks pretty corrupt. In just the last few months since she was appointed, there were concerns about her stock sales and stock purchases, which seemed oddly matched to information she was getting during briefings regarding the impact of COVID-19. She has since agreed to convert all her stock holdings to managed funds outside of her control (something every elected official should do, frankly).

Now, the NY Times is noting another form of what we've referred to as "soft corruption" -- moves that might technically be legal, but which sure look sketchy as hell to any regular non-multimillionaire elected official. In this case, Senator Loeffler received what was, in effect, a gift worth $9 million from her former employer, Intercontinental Exchange (the company that runs the NY Stock Exchange, and where her husband is the CEO).

The key issue was that since she was leaving the job to go join the Senate, she had a bunch of unvested stock. For normal people, if you leave a job before your stock vests, too bad. That's the deal. The vesting period is there for a reason. But for powerful, rich people, apparently the rules change. Intercontinental Exchange changed the rules to grant her the compensation that she wasn't supposed to get, because why not?

Ms. Loeffler, who was appointed to the Senate in December and is now in a competitive race to hold her seat, appears to have received stock and other awards worth more than $9 million from the company, Intercontinental Exchange, according to a review of securities filings by The New York Times, Ms. Loeffler’s financial disclosure form and interviews with compensation and accounting experts. That was on top of her 2019 salary and bonus of about $3.5 million.

The additional compensation came in the form of shares, stock options and other instruments that Ms. Loeffler had previously been granted but was poised to forfeit by leaving the company. Intercontinental Exchange altered the terms of the awards, allowing her to keep them. The largest component — which the company had previously valued at about $7.8 million — was a stake in an Intercontinental Exchange subsidiary that Ms. Loeffler had been running.

The entitlement factor oozes out of the statement put out from her office in response to this:

“Kelly left millions in equity compensation behind to serve in public office to protect freedom, conservative values and economic opportunity for all Georgians,” said Stephen Lawson, a spokesman for Ms. Loeffler. “The obsession of the liberal media and career politicians with her success shows their bias against private sector opportunity in favor of big government.”

No, Stephen, that's not the issue. The issue is that normal people who haven't vested yet, don't get to have the board change the vesting rules as you're leaving to go legislate in order to give you a $9 million windfall you didn't earn because it hadn't vested. If it had just been a question of compensation, no one would be complaining. If she had played by the rules that everyone else played by, lived up to her end of the contract and vested the equity, then no big deal. The problem is the last minute changing of the rules to get her a pretty massive payout (perhaps not by her standards, but by anyone else's).

Indeed, the details show that this wasn't just a timing thing, like a standard vesting deal, but that Loeffler was supposed to reach certain milestones to be able to get the equity. She didn't, but she still gets it. That's the part that has people concerned.

In February 2019, Intercontinental Exchange gave Ms. Loeffler a stake in a limited liability company that owned a stake in Bakkt, according to a March 2019 securities filing. The company at the time estimated the award was worth $15.6 million. But Ms. Loeffler would be able to cash in on the award only under certain circumstances, including if Bakkt’s value soared or if it became a publicly traded company.

When Ms. Loeffler stepped down from the company less than 10 months later, she was poised to forfeit much of that Bakkt stake. But Intercontinental Exchange sped up the vesting process so that she got half of it immediately.

The company, of course, puts a nice spin on it, saying "We admire Kelly’s decision to serve her country in the U.S. Senate and did not want to discourage that willingness to serve,” but what else are they going to say anyway?

Still waiting for that supposed swamp draining we keep hearing about.

The coronavirus pandemic and its associated lockdown in most countries has forced major changes in the way people live, work and study. Online learning is now routine for many, and is largely unproblematic, not least because it has been used for many years. However, online testing is more tricky, since there is a concern by many teachers that students might use their isolated situation to cheat during exams. One person's problem is another person's opportunity, and there are a number of proctoring services that claim to stop or at least minimize cheating during online tests. One thing they have in common is that they tend to be intrusive, and show little respect for the privacy of the people they monitor.

As an article in The Verge explains, some employ humans to watch over students using Zoom video calls. That's reasonably close to a traditional setup, where a teacher or proctor watches students in an exam hall. But there are also webcam-based automated approaches, as explored by Vox:

For instance, Examity also uses AI to verify students' identities, analyze their keystrokes, and, of course, ensure they're not cheating. Proctorio uses artificial intelligence to conduct gaze detection, which tracks whether a student is looking away from their screens.

It's not just in the US that these extreme surveillance methods are being adopted. In France, the University of Rennes 1 is using a system called Managexam, which adds a few extra features: the ability to detect "inappropriate" Internet searches by the student, the use of a second screen, or the presence of another person in the room (original in French). The Vox articles notes that even when these systems are deployed, students still try to cheat using new tricks, and the anti-cheating services try to stop them doing so:

it's easy to find online tips and tricks for duping remote proctoring services. Some suggest hiding notes underneath the view of the camera or setting up a secret laptop. It's also easy for these remote proctoring services to find out about these cheating methods, so they're constantly coming up with countermeasures. On its website, Proctorio even has a job listing for a "professional cheater" to test its system. The contract position pays between $10,000 and $20,000 a year.

As the arms race between students and proctoring services escalates, it's surely time to ask whether the problem isn't people cheating, but the use of old-style, analog testing formats in a world that has been forced by the coronavirus pandemic to move to a completely digital approach. Rather than spending so much time, effort and money on trying to stop students from cheating, maybe we need to come up with new ways of measuring what they have learnt and understood -- ones that are not immune to cheating, but where cheating has no meaning. Obvious options include "open book" exams, where students can use whatever resources they like, or even abolishing formal exams completely, and opting for continuous assessment. Since the lockdown has forced educational establishments to re-invent teaching, isn't it time they re-invented exams too?

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This seems to be something of a thing. Our last "Tales From the Quarantine" post focused on how television celebrities had taken to offering people help on Twitter with their virtual home decor in the latest Animal Crossing game. This post also involves Animal Crossing, but in a much more direct way. Due to the COVID-19 pandemic, there are enormous numbers of people who have suddenly found themselves without jobs or regular income. And, so, they've turned to irregular sources of income instead.

Ars Technica has an interesting interview with one of many people who have taken to the internet to indirectly sell Animal Crossing's "bells", the currency of the game.

In the midst of COVID-19, some New Horizons players are turning to World of Warcraft-style gold farming methods to make ends meet. In early April, Lexy, a 23-year-old recent college grad, created a Twitter account offering up bells (Animal Crossing’s in-game currency) for real-world cash (she requested we refer to her by a nickname to avoid potential reprisal from Nintendo). “I got laid off due to COVID so I'm farming bells in ACNH,” she wrote. “I really need to make rent this month so I'm selling 2 mil bells per $5, please message me if interested, I'll give you a discount the more you buy.”

Before setting up this unorthodox income stream, Lexy had been working at a supermarket while developing her animation portfolio. She began exploring the idea of turning bells into cash after showing friends just how much in-game income she’d been making. “One of them asked to legitimately buy some for me,” she recalled in a Twitter interview. “I did some research and found some people selling bells on sites such as eBay, but for pretty ridiculous prices.” (Current prices on eBay seem more competitive, with some sellers offering rare gold tools and gold nuggets to sweeten the deal).

The threat from Nintendo is probably real. After all, unlike some other games where people do this sort of thing, Nintendo's game doesn't include any method for selling in-game resources for real currency. Nintendo is also notoriously prudish about things like this. And, finally, to make an effective go at this sort of thing, it takes some manipulation of the console in a way that is somewhat controversial with gamers generally.

Understandably, Lexy adjusts the clock on her Nintendo Switch to speed up the game’s slow, “natural” money-making cycle of harvesting daily fruit, digging up bells from the ground, and planting a daily “money tree” that can yield big profits. This kind of in-game “time traveling” is controversial practice among casual Animal Crossing players, but it's a practical necessity to maximize real-world bell-farming profits.

As for how much money people like Lexy are bringing in, it's in the four figures, but she wasn't any more specific than that. Payments are made through digital apps like PayPal, after which she visits the game islands of others and deposits the bells.

That all of this is going on during a global pandemic that has some folks farming bells to make ends meet and others with apparently enough disposable income to be buyers is all, of course, deeply strange. But it's also just yet another way technology is having an impact on our lives during the COVID-19 pandemic.

In Matthew 7:15-19, Jesus tells His disciples how to tell good teachers from bad teachers. He tells them to look at the fruit. Is Jesus telling people to look at the lives of other teachers to see if they have good works? No! Not at all. Listen to the study to see what Jesus IS teaching and why this is important for properly understanding the gospel.

I recently travelled to Pittsburgh, USA, to present the paper “From Playing Games to Committing Crimes: A Multi-Technique Approach to Predicting Key Actors on an Online Gaming Forum” at eCrime 2019, co-authored with Ben Collier and Alice Hutchings. The accepted version of the paper can be accessed here. The structure and content of various underground … Continue reading From Playing Games to Committing Crimes: A Multi-Technique Approach to Predicting Key Actors on an Online Gaming Forum →

Recent advancements in Machine Learning (ML) have taught us two main lessons: a large proportion of things that humans do can actually be automated, and that a substantial part of this automation can be done with minimal human supervision. One no longer needs to select features for models to use; in many cases people are … Continue reading Three Paper Thursday: Adversarial Machine Learning, Humans and everything in between →

Just as in other types of victimization, victims of cybercrime can experience serious consequences, emotional or not. First of all, a repeat victim of a cyber-attack might face serious financial or emotional hardship. These victims are also more likely to require medical attention as a consequence of online fraud victimization. This means repeat victims have a … Continue reading Three Paper Thursday: Exploring the Impact of Online Crime Victimization →

Try some homestyle Chinese with this easy, healthy, and delicious bean sprout stir fry that takes just minutes to put on your dinner table!

craving more? check out TasteSpotting

ML eggheads, devs get more bang for their buck, say OpenAI duo

Machine-learning algorithms are improving in performance at a rate faster than that of the underlying computer chips, we're told.…

Microsoft, Cisco, Google etc gang up to form Open RAN Policy Coalition

Some of America’s super-corps have remembered how the US became the dominant global technology force it is, and have vowed to use innovation over threats to counter Chinese dominance in 5G markets.…

Lee Jae-yong ends dynastic control and will even let staff join a union

Samsung's heir has said that he will not pass down management of the South Korean conglomerate to his children, ending three generations dynastic rule.…

'B' is for basic controls that up and disappeared

A study of the UK online advertising market, conducted by global accounting firm PwC, has found that publishers get just half of what advertisers spend, with the other half siphoned off by ad-supply chain intermediaries.…

Advertise your open positions here for free, no catch, and find opportunities within

Job Alert This week we've got job openings from all over the globe to tempt you, your friends or your past colleagues back into work, or indeed into new ventures.…

And now to avoid container sprawl costing you plenty

Microsoft has slipped out licensing details for SQL Server running in containers and it will likely encourage developers to be pretty diligent in their use of Redmond’s database.…

Interior decoration is a tremendously crucial element of any kind of dining establishment. If you are in the planning stages of opening up a dining establishment, if you already own one and also are thinking about making adjustments, you will… Continue Reading →

At Let Grow, a wise mom named Kate Sundquist admits that while her kids were already good at playing, they certainly weren’t good at filling hours and hours of free time, playing by themselves. (Read the piece here.) So she her and boys created a schedule. “While these routines might seem restrictive or even the […]

At least for some kids, yes, being flung from the stress of a super-structured, super-supervised existence is having a calming, life-expanding effect. I discuss this amazing phenom in this Big Think article, including six short essays by kids themselves, and also in this interview with Bored Panda,  the  pop culture site, where I note that […]

The incentive to automate will be enormous for $15 per hour minimum wage. Of America’s nearly 16 million retail workers, the biggest group — 4.6 million — are salespeople. Their average wage is $10.47 an hour. After that, the country has another 3.4 million cashiers, and their average wage is $9.28 an hour. Only a quarter of salespeople earn more than $14 — and only 10 percent earn more than $19. The figures are worse for cashiers. But in the race to automate there will be a clear winner: Amazon. Why: Amazon can automate more easily than can physical stores. It is analogous to why long haul trucking can be automated before taxis: Just as highways are simpler places than...

By 2060 Phoenix Arizona will have 132 days a year over 100F. Dallas will 55 and Pecos Texas 101 days. My view about problems: We should solve them. If the Earth really does heat up substantially then we should pull the CO2 back out of the atmosphere while also releasing cooling gases. If its practical we should also raise the albedo (surface reflectivity) of the planet. Right now cities should change their zoning laws and roads policies to make buildings, roads, and other surfaces more reflective. No more dark buildings. Use light colors of concrete, white shingles, and other surfaces that reflect more light. That would be beneficial even if the Earth was not heating up. Hot cities are unpleasant...

In a nutshell: editing offspring DNA at the embryo stage will eventually offer so many advantages that lots of people will cave in on some advantage. Don't want to make your kid smarter? Make him or her better looking? Don't want that? How about a throwing arm competitive in major league baseball? Opposed to that? How about avoiding passing along your terrible allergies, need for braces, terrible eyesight, tendency to get depressed or perhaps anxiety attacks or eating disorders? Lots of ways to be persuaded to step over the line once the tech becomes safe. If asked whether one would genetically engineer one's offspring today many people would answer "No" to the hypothetical question. But today choosing genes for your...

Check out: The FDA Is Cracking Down On Rogue Genetic Engineers. Apparently the US Food and Drug Administration wants to classify genetically altered dogs as drugs. When this is done to humans will they become drugs too? I think Huey Lewis has foreseen this possibility. A substantial part of the population is going to continue to insist on owning highly inbred genetically messed up dog breeds with serious health issues (e.g. bulldogs and pugs). If you do not want to me like them then avoid the unhealthiest dog breeds. But given that these breeds will continue to exist it certainly makes sense to genetically fix the fixable ones (some are, by breed standard, probably not fixable). So genetic engineers who...

La semaine dernière les contes de fées ont été lus dedans 13 langues : Anglais, français, allemand, italien, chinois, danois, espagnol, portugais, coréen, japonais, grec, russe et néerlandais.

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On accorde "The World of Art Award" (WAA) aux artistes, aux galeries et aux musées qui poursuivent les "meilleures pratiques" dans l'art et la culture. Cette concurrence cherche à attirer dies artistes, galeries, les musées qui redéfinissent des normes de l'excellence d'art. Ceux qui défie des trends et des tendances existantes dans l'art et la culture.

Do you have a fear of standing alone at your company party with nobody to talk to and no way to break the ice? Have no fear, F&J is here! Here’s a quick and dirty arsenal of one-liner jokes that are sure to make you the life of the party. Rest assured that nobody will […]

The post 11 Crappy One-Liners Sure To Leave You A Loser appeared first on Funny & Jokes.

Грузия отозвала посла из Украины для консультаций в связи с назначением экс-президента страны Михеила Саакашвили главой исполнительного комитета реформ Украины. Об этом в пятницу, 8 мая, заявил глава МИД Грузии Давид Залкалиани.

Levodopa-induced dyskinesia (LID) poses a significant health care challenge for Parkinson’s disease (PD) patients. Amantadine is currently the only drug proven to alleviate LID. Although its efficacy in treating LID is widely assumed to be mediated by blockade of N-methyl-D-aspartate (NMDA) glutamate receptors, our experiments demonstrate that at therapeutically relevant concentrations, amantadine preferentially blocks inward-rectifying K+ channel type 2 (Kir2) channels in striatal spiny projection neurons (SPNs) — not NMDA receptors. In so doing, amantadine enhances dendritic integration of excitatory synaptic potentials in SPNs and enhances — not antagonizes — the induction of long-term potentiation (LTP) at excitatory, axospinous synapses. Taken together, our studies suggest that the alleviation of LID in PD patients is mediated by diminishing the disparity in the excitability of direct- and indirect-pathway SPNs in the on state, rather than by disrupting LTP induction. This insight points to a pharmacological approach that could be used to effectively ameliorate LID and improve the quality of life for PD patients.

The renaissance of complement diagnostics and therapeutics has introduced precision medicine into a widened field of complement-mediated diseases. In particular, complement-mediated diseases (or complementopathies) with ongoing or published clinical trials of complement inhibitors include paroxysmal nocturnal hemoglobinuria, cold agglutinin disease, hemolytic uremic syndrome, nephropathies, HELLP syndrome, transplant-associated thrombotic microangiopathy, antiphospholipid antibody syndrome, myasthenia gravis, and neuromyelitis optica. Recognizing that this field is rapidly expanding, we aim to provide a state-of-the-art review of (a) current understanding of complement biology for the clinician, (b) novel insights into complement with potential applicability to clinical practice, (c) complement in disease across various disciplines (hematology, nephrology, obstetrics, transplantation, rheumatology, and neurology), and (d) the potential future of precision medicine. Better understanding of complement diagnostics and therapeutics will not only facilitate physicians treating patients in clinical practice but also provide the basis for future research toward precision medicine in this field.

Regenerative pain medicine, which seeks to harness the body’s own reparative capacity, is rapidly emerging as a field within pain medicine and orthopedics. It is increasingly appreciated that common analgesic mechanisms for these treatments depend on neuroimmune modulation. In this Review, we discuss recent progress in mechanistic understanding of nociceptive sensitization in chronic pain with a focus on neuroimmune modulation. We also examine the spectrum of regenerative outcomes, including preclinical and clinical outcomes. We further distinguish the analgesic mechanisms of regenerative therapies from those of cellular replacement, creating a conceptual and mechanistic framework to evaluate future research on regenerative medicine.

The physical integrity of endothelial cells (ECs) lining the blood vessels regulates the inflammatory response. Both innate immunity and inflammatory disorders hinge on the EC-neutrophil interaction. Neutrophil binding, rolling, and migrating along and between ECs is associated with vascular permeability. In this issue of the JCI, Owen-Woods et al. tracked neutrophils in vivo in venules of mouse striated muscle and revealed how endothelial permeability can affect neutrophil trafficking. Strikingly, many neutrophils that migrated between EC junctions were able to rejoin the blood circulation. Further, the chemokine and neutrophil chemoattractant, CXCL1, drove this reverse transendothelial migration (rTEM). This paradigm-shifting study provides a mechanism for distal organ damage as well as an explanation for sepsis-associated acute respiratory distress syndrome.

BACKGROUND The live attenuated BPZE1 vaccine candidate induces protection against B. pertussis and prevents nasal colonization in animal models. Here we report on the responses in humans receiving a single intranasal administration of BPZE1.METHODS We performed multiple assays to dissect the immune responses induced in humans (n = 12) receiving BPZE1, with particular emphasis on the magnitude and characteristics of the antibody responses. Such responses were benchmarked to adolescents (n = 12) receiving the complete vaccination program of the currently used acellular pertussis vaccine (aPV). Using immunoproteomics analysis, potentially novel immunogenic B. pertussis antigens were identified.RESULTS All BPZE1 vaccinees showed robust B. pertussis–specific antibody responses with regard to significant increase in 1 or more of the following parameters: IgG, IgA, and memory B cells to B. pertussis antigens. BPZE1–specific T cells showed a Th1 phenotype, and the IgG exclusively consisted of IgG1 and IgG3. In contrast, all aPV vaccines showed a Th2-biased response. Immunoproteomics profiling revealed that BPZE1 elicited broader and different antibody specificities to B. pertussis antigens as compared with the aPV that primarily induced antibodies to the vaccine antigens. Moreover, BPZE1 was superior at inducing opsonizing antibodies that stimulated ROS production in neutrophils and enhanced bactericidal function, which was in line with the finding that antibodies against adenylate cyclase toxin were only elicited by BPZE1.CONCLUSION The breadth of the antibodies, the Th1-type cellular response, and killing mechanisms elicited by BPZE1 may hold prospects of improving vaccine efficacy and protection against B. pertussis transmission.TRIAL REGISTRATION ClinicalTrials.gov NCT02453048, NCT00870350.FUNDING ILiAD Biotechnologies, Swedish Research Council (Vetenskapsrådet), Swedish Heart-Lung Foundation.