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Addressing Social Determinants of Health at Well Child Care Visits: A Cluster RCT

Although pediatric professional guidelines emphasize addressing a child’s social environment in the context of well child care, it remains unclear whether screening for unmet basic needs at visits increases low-income families’ receipt of community-based resources.

This study demonstrates that systematically screening and referring for social determinants of health during primary care can lead to the receipt of more community resources for families. (Read the full article)




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Cognitive-Behavioral Counseling for Exclusive Breastfeeding in Rural Pediatrics: A Cluster RCT

Exclusive breastfeeding until 6 months of an infant’s age is described as the safest, most powerful and cost-effective intervention to reduce infant morbidity and mortality globally. In developing countries, only ~25% of infants are exclusively breastfed for 6 months.

We developed a psycho-educational intervention combining education with techniques of cognitive-behavioral therapy, integrated it into the routine work of community health workers, which increased the rate and duration of exclusive breastfeeding until 6 months of an infant’s age. (Read the full article)




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Adolescents' Perceptions of Light and Intermittent Smoking in the United States

Light and intermittent smoking are harmful, but increasingly common, smoking patterns. It is unknown how adolescents perceive these smoking patterns, and whether these views differ by sociodemographic characteristics, and exposure to and use of tobacco.

US adolescents perceive light and intermittent smoking as significantly less dangerous than heavier smoking. One in 4 adolescents believes intermittent smoking causes little to no harm. Perceptions of relative safety were common among smokers. (Read the full article)




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Cardiovascular Risk Factors in Children After Repeat Doses of Antenatal Glucocorticoids: An RCT

Administration of repeat doses of antenatal glucocorticoids to women at risk for preterm birth after an initial course reduces neonatal morbidity, without affecting rates of neurologic disability in early childhood. However, data on long-term effects on cardiometabolic health are limited.

Exposure to repeat doses of antenatal betamethasone did not increase cardiovascular risk factors at early school age. Clinicians wishing to use repeat antenatal glucocorticoids can be reassured that the risk of future cardiometabolic disease from this therapy is low. (Read the full article)




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Oropharyngeal Colostrum Administration in Extremely Premature Infants: An RCT

Immune-related bioactive proteins are highly concentrated in the colostrum of mothers who deliver preterm infants. Oropharyngeal administration was proposed as a safe and feasible alternative method of providing colostrum to immunocompromised premature infants.

Oropharyngeally administered colostrum during the first few days of life increased urinary secretory immunoglobulin A and lactoferrin, decreased urinary interleukin-1β, reduced salivary transforming growth factor-β1 and interleukin-8, and reduced the occurrence of clinical sepsis in extremely premature infants. (Read the full article)




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Childhood Behavior Problems and Age at First Sexual Intercourse: A Prospective Birth Cohort Study

Early first sexual intercourse (FSI) is a risk factor for unplanned teenage pregnancy, sexually transmitted infection, and adverse health outcomes in adolescence and into adulthood. In girls, externalizing behaviors are more strongly associated with earlier FSI than internalizing behaviors.

Externalizing behavior from as early as 5 in boys and 10 in girls is a significant risk factor for earlier age at FSI. Internalizing behavior at ages 8 and 10 was associated with early FSI for boys but not girls. (Read the full article)




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Strategic Modeling of the Pediatric Nurse Practitioner Workforce

The number of nurse practitioner graduates in the United States has nearly doubled over the past 2 decades. However, the number of pediatric nurse practitioner (PNP) graduates has remained relatively flat, although the demand for PNPs is expected to increase.

This study estimates the best-case shortage of PNPs over the next 25 years. We propose possible policy interventions to address key areas of the PNP workforce system and we compute their impact on the forecasted PNP shortage. (Read the full article)




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Motivational Interviewing With Parents for Obesity: An RCT

Motivational interviewing (MI) has been found to increase the effectiveness of weight loss programs in obese children and adolescents. Although parental involvement seems to be linked to its effectiveness, strong conclusions cannot be drawn.

The present study found that MI with parental involvement is an effective strategy in changing obesity-related outcomes and has additional effects beyond MI with adolescents only. These findings are important when administering MI interventions in school settings. (Read the full article)




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Noninvasive Ventilation Strategies for Early Treatment of RDS in Preterm Infants: An RCT

Noninvasive ventilation (NIV) reduced the need of intubation in preterm infants with RDS. However, randomized studies comparing nasal synchronized intermittent positive pressure ventilation and bilevel continuous positive airway pressure are still lacking.

The present study shows no differences in short-term outcomes between 2 different NIV strategies, nasal synchronized intermittent positive pressure ventilation and bilevel continuous positive airway pressure, in preterm infants for the initial treatment of RDS. (Read the full article)




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Diet, Exercise, and Endothelial Function in Obese Adolescents

Adolescent obesity is characterized by endothelial dysfunction at the macrovascular and microvascular level; high endothelial microparticle (EMP) and low endothelial progenitor cell (EPC) counts contribute to these processes. Although reversal of macrovascular endothelial dysfunction is feasible, clinical evidence regarding microvascular endothelial dysfunction is scarce.

Ten months of diet and exercise training improves microvascular endothelial function (peak response) in obese adolescents. EPC and EMP displayed a biphasic response, with an increase in EPC at 5 months and a decrease in EMP at the end of the treatment. (Read the full article)




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Sucrose and Warmth for Analgesia in Healthy Newborns: An RCT

Increasing data suggest that neonatal pain has long-term consequences. Pharmacologic interventions for minor pain are ineffective, and nonpharmacologic techniques (sucrose taste, pacifier suckling, breastfeeding) are effective and now widely used.

The taste of sucrose has been shown to be an effective and widely used analgesic for infants, and this study demonstrates that combining brief exposure to natural radiant warmth with the taste of sucrose improves the analgesic effect for the infant. (Read the full article)




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Parent-Reported Outcomes of a Shared Decision-Making Portal in Asthma: A Practice-Based RCT

Strategies are needed to engage families of chronically ill children at home in an ongoing process of shared decision-making regarding treatment that is responsive to families’ concerns and goals and children’s evolving symptoms.

This study evaluated a novel patient portal that facilitates shared decision-making in asthma. The portal was feasible and acceptable to families, improved outcomes, and provides a model for improving care through an electronic health record portal. (Read the full article)




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Continuous Positive Airway Pressure With Helmet Versus Mask in Infants With Bronchiolitis: An RCT

In a previous short-term physiologic randomized controlled trial, continuous positive airway pressure by helmet was feasible and efficient in improving gas exchange in pediatric acute respiratory failure due to bronchiolitis.

Continuous positive airway pressure administered by helmet reduces the rate of noninvasive respiratory support failure and provides longer application time with less sedation than a facial mask. In addition, it is safe to use and free from adverse events. (Read the full article)




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Motivational Interviewing and Dietary Counseling for Obesity in Primary Care: An RCT

Childhood obesity rates in the United States remain at historic highs. The pediatric primary care office represents an important, underutilized source of intervention. There is a need to test the efficacy of motivational interviewing for pediatric obesity in primary care.

This is among the first large-scale randomized trials to show significant reductions in BMI and that motivational interviewing, delivered by trained providers in the primary care setting, can be an important and feasible part of addressing childhood obesity. (Read the full article)




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Cow's Milk Contamination of Human Milk Purchased via the Internet

Sharing human milk between those with an abundant supply and those seeking milk for their child is growing in popularity, including that facilitated by Web sites established to link buyers and sellers.

This study documents that human milk purchased via the Internet can be contaminated with cow’s milk, which poses a potential risk to infants with allergy or intolerance to cow’s milk. (Read the full article)




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Parenting Skills and Emotional Availability: An RCT

Early parenting programs benefit children’s development in low- and middle-income countries. However, the extent to which these interventions have a positive impact on parenting skills and their emotional availability is less studied.

An early child development intervention using play and communication activities to promote caregivers’ responsiveness can improve mother–child interactions, caregiving environment, caregiving practices pertaining to development and feeding, and, in combination with a nutrition intervention, support maternal emotional well-being. (Read the full article)




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Long-Chain Polyunsaturated Fatty Acids and Cognition in VLBW Infants at 8 years: an RCT

Suboptimal brain development and increased risk of cognitive deficits are well documented in very low birth weight children. Supplementation with docosahexaenoic acid and arachidonic acid has been associated with positive cognitive effects.

This follow-up study of a randomized controlled trial of supplementation with docosahexaenoic acid and arachidonic acid to very low birth weight infants is the first report on both cognition and brain macrostructure measured with MRI. No cognitive or neuroanatomical effects were detected at 8 years. (Read the full article)




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Global and Regional Burden of Isoniazid-Resistant Tuberculosis

Fifteen percent of tuberculosis cases globally are resistant to the drug isoniazid. Isoniazid resistance puts patients with tuberculosis at risk for poor treatment outcomes and threatens the effectiveness of isoniazid preventive therapy in people with latent tuberculosis infection.

We present the first global and regional estimates of the proportion of children with tuberculosis who have isoniazid-resistant disease, showing large geographic variations in risk of resistance. We estimate the number of annual incident cases of isoniazid-resistant tuberculosis in children. (Read the full article)




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Public Perceptions of the Benefits and Risks of Newborn Screening

Infant screening is valued by members of the lay public, but how different benefits are independently valued, and whether harms are disvalued, is not known. Public expectations of screening can inform decisions about what diseases to screen for.

The public values clinical benefits of screening and disvalues harms, with tolerance for harm proportional to clinical benefit. These findings support newborn screening policies prioritizing clinical benefits over solely informational benefits, coupled with concerted efforts to avoid or minimize harms. (Read the full article)




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Late Diagnosis of Coarctation Despite Prenatal Ultrasound and Postnatal Pulse Oximetry

Neonatal coarctation of the aorta (CoA) is a life-threatening cardiac defect, but because symptoms may be lacking initially, newborns with this defect are frequently discharged from the hospital undiagnosed. Delayed diagnosis of CoA is associated with increased morbidity and mortality.

This population-based study analyzes the contribution of prenatal ultrasound and postnatal pulse oximetry screening to the timely diagnosis of neonatal CoA. Both screening methods had low sensitivity for CoA. Nearly half of all newborns with isolated CoA were discharged undiagnosed. (Read the full article)




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Inappropriate Use of Ultrasound in Management of Pediatric Cryptorchidism

The value of ultrasound imaging for the diagnosis, prognosis, and surgical planning of cryptorchidism is limited at best.

Ultrasound remains grossly overused by referring physicians throughout Ontario, Canada, which resulted in a 3-month delay to definitive surgery and unnecessary expenditures. (Read the full article)




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Two-Year Outcomes of a Population-Based Intervention for Preschool Language Delay: An RCT

Preschool language delay predicts poorer academic performance, employment opportunities, and social relationships. Language for Learning, a systematic, population-based intervention for 4-year-olds with low language, is feasible, acceptable and has short-term benefits, but long-term benefits are unknown.

Population ascertainment at age 4 followed by a yearlong, one-on-one home program benefited phonological skills (an important literacy determinant) at age 6, but not the primary language outcomes. To be cost-effective, future follow-up would need to demonstrate lasting academic benefits. (Read the full article)




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Sources of Infant Pertussis Infection in the United States

The source of infant pertussis infection is typically identified ~50% of the time. Historically, mothers have been identified as the most common source of pertussis transmission to infants.

This analysis of 8 years of enhanced pertussis surveillance data has uncovered a shift in the most common source of infant pertussis infection in the United States from mothers to siblings. (Read the full article)




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Risk Factors for Central Nervous System Tuberculosis

Central nervous system (CNS) tuberculosis has high morbidity and mortality, and it frequently affects children aged <5 years.

In California, children who were US-born, Hispanic, and aged <5 years were at increased risk of CNS tuberculosis. Children with CNS tuberculosis were more likely to die. Specific populations of US-born infants might benefit from additional prevention measures. (Read the full article)




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Long-term Effects of Pediatric Burns on the Circulatory System

Systemic responses occur after burn injury that lead to widespread changes to the body, including the heart. Elevated levels of catecholamines and stress hormones have been found up to 3 years after severe burns. Little is known about the longer-term effects.

Children with burns had 1.3 times as many admissions and 2.3 times the number of days in hospital for circulatory diseases compared with uninjured children. Children with minor burns had an increased risk of incident admissions for circulatory diseases. (Read the full article)




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Apple Enables iOS In-App Purchase Gifting

Before now, you could gift a paid iOS app, but not paid in-app purchases. An update to the review guidelines changes this, most likely as a reaction to more paid content only being available through in-app purchases.




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March 24 Open House




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Two Great Valley professors awarded seed grants for COVID-19 research

Ashkan Negahban, assistant professor of engineering management, and Satish Srinivasan, assistant professor of information science, will lead projects that help address the COVID-19 crisis, thanks to seed grants from the Huck Institutes of the Life Sciences.




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Researchers Probe Connections Between Math, Reading Difficulties

Students with dyslexia often struggle with math fluency as well, and scholars at a recent conference put a spotlight on some of the possible connections.




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Half-Life: Alyx to Launch in March, But Requires VR Headset

On Thursday, Valve showed off footage for Half-Life: Alyx, which will be set before the events of Half-Life 2. Instead of using a mouse and keyboard, you'll need a VR headset to play it.




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Arcade1Up Adds Wi-Fi to 4-Player NBA Jam Cabinet

The new Arcade1Up NBA Jam cabinet is the first to feature Wi-Fi internet connectivity, enabling multiplayer with other cabinet owners.




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Nvidia GeForce Now

Nvidia's GeForce Now streaming service lets you play many games from your Steam library on nearly any device.




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Researchers explore quantum computing to discover possible COVID-19 treatments

Quantum machine learning, an emerging field that combines machine learning and quantum physics, is the focus of research to discover possible treatments for COVID-19, according to Penn State researchers, who believe that this method could be faster and more economical than the current methods used for drug discovery.




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Barcelona in sight of unique double

Barcelona made the UEFA Women's Champions League final and could reach the men's decider too, setting up an unprecedented feat.




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Lyon v Barcelona: #UWCL final – all you need to know

Lyon will play their eighth final in a decade while Barcelona are there for the first time when they meet in Budapest on Saturday.




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The Teaching Force Is Mostly Female. Is That Bad for Boys?

A new brief from the Brookings Institution poses the question: Is overrepresentation of women in the teaching force negatively affecting boys' achievement?




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Explore, discover and define your future at March 28 open house

From 9 a.m. to 3 p.m. Saturday, March 28, members of the Penn College community will welcome thousands of potential enrollees and their families, opening wide the doors to a landmark institution that has helped tomorrow makers fulfill their destinies for more than a century.




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Fierce Debate as DeVos Weighs Schools' Obligations to Students With Disabilities

Amid coronavirus-related school closures, advocates worry Education Secretary Betsy DeVos may waive requirements of special education law if Congress signs off. Schools say it's difficult to meet some requirements during the pandemic.




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Today's Deals: Get 35 Percent Off SanDisk Storage

You won't want to miss these great deals.




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Circle football drill II

A drill focused on improving movement, teamwork and making the most of scoring chances.




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Pearce on full-backs

England U21 coach Stuart Pearce discusses a position he used to master.




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Barcelona's Lionel Messi

FC Barcelona's talisman tells us about his appetite for goals.




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Latvia's tactical masterclass

We analyse how Latvia secured a point against Germany at UEFA EURO 2004.




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Pleat on Barcelona's 4-3-3

Former Tottenham Hotspur FC manager David Pleat analyses FC Barcelona's winning formation from 2009.




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Research Center's Leadership Professional-Development Program Had No Impact. Why?

A recent study found that one organization's instructional-leadership professional development had no impact. Could it be because the topic of instructional leadership needs to be expanded?




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When Teaching Media Literacy, Which News Sources Are Credible? Even Teachers Don't Agree

Like other Americans, liberal and conservative teachers perceive news sources' credibility differently. How does that affect their teaching of media literacy?




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Teachers Share Resources for Teaching Online During Coronavirus School Closures

To help ease the transition to remote instruction, educators have launched virtual professional learning communities to share resources, ask questions, and give advice.




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High Stakes for Schools If 2020 Census Undercounts Latino Families

For communities with significant numbers of Latino and immigrant residents, the barriers to an accurate 2020 Census count are high—and so are the stakes for their schools, which could lose hundreds of millions of dollars if counts are inaccurate.




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FCCC/ARR/2017/GRC

Greece. Report on the individual review of the annual submission of Greece submitted in 2017. Note by the expert review team.




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'Feed the Future' grant to support women's empowerment research project in Ghana

A $450,000 grant from the U.S. Agency for International Development’s Feed the Future Innovation Lab for Peanut Research will aid researchers in Penn State’s College of Agricultural Sciences as they explore the potential to empower women farmers in northern Ghana through peanut production.