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PIX: Real Madrid back to winning ways; Leverkusen held

Real Madrid have avoided defeat in their last 41 LaLiga games, the second best streak by a team in the competition's history.




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Nadal - The Highs, Lows and everything in between!

Here is a quick glance of all the highs and lows from Nadal's stupendous career:




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PIX: Barca thrash Sevilla; Atletico win

Robert Lewandowski and substitute Pablo Torre each scored twice to help leaders Barcelona thrash visitors Sevilla 5-1 in LaLiga on Sunday in a confidence boost for Hansi Flick's side ahead of key clashes against Bayern Munich and Real Madrid.




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Bundesliga PIX: Bayern win; champions Leverkusen held

Bayern Munich earned a nervous 1-0 win at St Pauli thanks to a sensational 28-metre drive from Jamal Musiala to stay unbeaten.




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13/13:01 EDT Severe Thunderstorm Warning for parts of East Gippsland Forecast District.




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Can microbial communities regenerate? [electronic resource] : uniting ecology and evolutionary biology / S. Andrew Inkpen and W. Ford Doolittle.

Chicago, IL : The University of Chicago Press , 2022.




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Revolutionising data security: IBM introduces Guardium Data Security Centre with GenAI capabilities

The centre incorporates GenAI features for generating risk summaries and improving productivity among security teams.




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Bharti Airtel Q2 preview: Consolidated net profit expected to grow multifold

According to analysts, industry-leading ARPU and support from other businesses bode well for Airtel’s revenue growth during the quarter




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Zebra Technologies aims for double-digit revenue growth from India by next year

Zebra Technologies has expanded its India presence this year, particularly in sales and support functions to serve the growing demand




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GitHub has over 17 million Indian developers on its platform

India also has the second-highest number of GitHub Education users, second-highest number of contributors to public generative AI projects, and the second-highest number of contributions to open source projects—underscoring India’s rise as a global technology leader




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A Telugu novel’s stupendous success revives hopes for book publishing

‘Amma diarylo konni pageelu’ by a techie is sold over one lakh copies, backed by social media posts




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Apple reports record revenue in India; to launch 4 more stores in the country

Tim Cook calls out record India performance




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Progress targets $1 billion revenue with acquisition; expands Bangalore team

The ShareFile business the company is acquiring generates approximately $240 million in revenue




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Satcom spectrum: TRAI sidestepped level field issue with terrestrial services, says Justice Nageswara Rao

His legal opinion, requested by Reliance Jio, highlights TRAI’s failure to invite stakeholder comments on the important issue of creating a level playing field between terrestrial access services and satellite communication networks




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C-DOT, IIT-Roorkee tie-up to develop millimeter wave transceiver for 5G rural connectivity

The project focuses on the development of millimeter wave backhaul technology in which only a small number of small cell-based stations are connected to the gateway through fibre




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Sonata Software optimistic about revenue growth in H2FY25; eyes $1.5 billion revenue by FY27

The company’s international services revenue in the September-ended quarter stood at ₹707.9 crore




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AI adoption: 74% companies struggle to achieve and scale value, says BCG

Report to assess firms’ AI maturity is based on a survey of 1,000 CxOs and senior executives from over 20 sectors, spanning 59 countries




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Good triumphs over evil

July 31 and August 1 are important days for the people living in Zanskar mountains as they celebrate Karsha Gustor.




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Synthesis of Asp-based lactam cyclic peptides using an amide-bonded diaminodiacid to prevent aspartimide formation

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00472H, Communication
Wen-Jie Li, Jun-You Chen, Hui-Xia Zhu, Yi-Ming Li, Yang Xu
A diaminodiacid (DADA) containing an amide bond can be used in Fmoc solid-phase peptide synthesis (SPPS) of an Asp-based lactam cyclic peptide with no aspartimide formation.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Revisiting Biginelli-like Reactions: Solvent Effects, Mechanisms, Biological Applications and Correction of Several Literature Reports

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00272E, Paper
Brenno A. D. Neto, Pedro Beck, Arthur Leitão, Yasmin Santana, Jose R. Correa, Carime Vitória da Silva Rodrigues, Daniel Machado, Guilherme Matos, Luciana Machado Ramos, Claudia Cristina Gatto, Carlos Kleber Z. Andrade, Sarah Caldas
This study critically reevaluates reported Biginelli-like reactions using a Kamlet-Abboud-Taft-based solvent effect model. Surprisingly, structural misassignments were discovered in certain multicomponent reactions, leading to the identification of pseudo three-component derivatives...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design, synthesis, biological evaluation and molecular docking studies of quinoline-anthranilic acid hybrids as potent anti-inflammatory drugs

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00040D, Paper
Sidra Siddique, Khalid Hussain, Naureen Shehzadi, Muhammad Arshad, Muhammad Nadeem Arshad, Sadaf Iftikhar, Farhat Saghir, Ayisha Shaukat, Muhammad Sarfraz, Nisar Ahmed
Despite the high global prevalence, rheumatoid arthritis lacks a satisfactory treatment.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Recent developments in the enzymatic modifications of steroid scaffolds

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00327F, Review Article
Open Access
Huibin Wang, Ikuro Abe
This review highlights the recent advancements in the enzymatic modifications of steroid scaffolds, emphasizing enzymatic hydroxylation, ketoreduction, dehydrogenation, enzymatic cascade reactions, and other modifications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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DevTools Digest - Chrome 35: Updates to the Developer Tools in Chrome 35

Updates to the Chrome Developer Tools: CSS property quick search, memory stats for heap snapshots, CodeMirror upgrade and more.




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Why Mount Everest is a no-fly zone

Hurricane-force winds and frequent snowstorms are obstacles




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Corporate travel is unlikely to reach pre-Covid levels

However, with offices opening up, many airlines are seeing increased demand with an uptick for premium cabins




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First-ever gravity-defying plane swap set for April 24

Two pilots will swap planes mid-air




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Evolution of security in aviation

Data and technology need to be adopted




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Thrust reversal in aircraft

It functions by directing the thrust produced by the plane’s jet engines forward, rather than backwards




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Hope you never get into a ‘coffin corner’ while flying

This situation occurs when the aircraft’s low-speed stall and high-speed buffet meet




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Reviving businesses will benefit from air cargo’s growth

India’s air cargo industry is well positioned to scale up further, thanks to a strong airport cargo infrastructure




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Google to develop AI that takes over computers: Report

Google is developing AI technology that takes over a web browser to complete tasks such as research and shopping, The Information reported




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GitHub unveils multi-model Copilot, Spark for AI developers

Anthropic’s Claude 3.5 Sonnet will be available via GitHub Copilot starting today and Google’s Gemini 1.5 Pro will be available in the coming weeks




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Chinese researchers develop AI model for military use on back of Meta's Llama

ChatBIT was fine-tuned and "optimised for dialogue and question-answering tasks in the military field", the paper said




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Amazon's improving retail sales boost third-quarter profit, revenue beats estimates

Like its tech peers, Amazon said it expected higher capital expenditures for the foreseeable future to help develop artificial intelligence software




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WHO to evacuate 1,000 Gazan women, children for urgent medical care

Last week, U.N. investigators said Israel was deliberately targeting health facilities in Gaza, and killing and torturing medical personnel there, accusing the country of "crimes against humanity".




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Centre eyes ‘presumed consent’ for cornea retrieval in hospital deaths

THOTA may be amended to facilitate retrieval of cornea from all Indians who die in hospitals, without family consent. 




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OpenAI’s Whisper transcription tool used in hospitals invents things no one ever said, researchers claim

Whisper is a popular transcription tool powered by artificial intelligence, but it has a major flaw




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Roll back approval to import used medical devices, med-tech industry urges PM

The group said the move puts at risk patient safety and undermines the domestic med-tech sector. It said that refurbished machines are not subject to stringent quality checks applicable to new devices.




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Doctors stress healthy lifestyle, regular check-up to prevent strokes in young adults

The webinar was held as part of The Hindu’s Wellness Series




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Tuberculosis infected 8 million people last year, the most WHO has ever tracked

The World Health Organization says more than 8 million people were diagnosed with tuberculosis last year




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ICMR invites expression of interest from firms for making anaemia detection device

The council wants to expand the effective screening network of anaemia among different age populations across India




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Telemedicine in India: is the government’s eSanjeevani platform living up to its potential?

While the eSanjeevani numbers are impressive, doctors and experts point out that unless a number of systemic issues -- including low doctor numbers on the platform are fixed -- telemedicine in the country will not be able to move past infancy




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Following WHO guidelines for sodium content in packaged food could prevent 3 lakh deaths in India in 10 years: study

Additionally, about 1.7 million new cardiovascular disease cases and 7,00,000 new chronic kidney disease cases could be prevented compared to current practices, the study said




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How to overcome your device dependency and manage a successful digital detox

There are four key strategies that are key to helping you achieve a healthier digital balance: replacement practices, social bonds, mindfulness and viewing digital well-being as a journey




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Lassa fever: Understanding the risk, response and global threat

The Lassa virus causes Lassa fever, a zoonotic disease; humans usually contract the virus through contact with food or items contaminated by the the Mastomys rat’s urine or faeces.




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Osteoporosis can shorten your life − here’s how to prevent fractures and keep bones healthy

The key to having healthy bones for a lifetime is to take some simple preventive measures – and the earlier, the better




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Can mid-level healthcare providers compensate for physician shortages in rural India?

To make up for doctor shortages, several countries around the world have introduced a cadre of MLHPs into their health systems; however, in India, mainstreaming of MLHPs has time and again been met with resistance from organised medicine 




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Severe staff shortage leaves Tamil Nadu’s obstetricians and gynaecologists overworked

Doctors are forced to take turns doing frequent 24-hour shifts — in some cases two to three 24-hour shifts a week. Inquiries with government OB-GYNs reveal that several health facilities have been short-staffed for years, and vacant posts remain unfilled




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Revealed: YouTube's India Plans

'Two in three creators in India who earn money from YouTube agree that YouTube is their primary source of revenue.'




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'Men, women, everybody, we want love'

'When something like this happens, it's just like all the weight and all the time that there was no work and the auditions were not cracking, you feel it's just worth it.'