Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics  Nature.com

Optimizing differential expression analysis for proteomics data via high-performing rules and ensemble inference  Nature.com

Deep Plasma Proteomics with Data-Independent Acquisition: Clinical Study Protocol Optimization with a COVID-19 Cohort  ACS Publications

Over the past two decades, there's been a sort of tectonic economic shift happening under our feet. More and more companies have switched from selling goods one by one to selling services, available as a subscription. These days everything from razor blades to meal kits to car washes have become subscriptions. But all that convenience has also come with a dark side – some companies have designed their offerings to be as easy as possible to sign up for and also as difficult as possible to cancel. Many consumers are now paying for way more subscriptions than they even know about.

On today's show, we discover how we all fell into this subscription trap – who is winning and who is losing in this brave new subscription based world – and what both the government and the free market are doing to try and fix it.

This episode was hosted by Alexi Horowitz-Ghazi and Jeff Guo. It was produced by James Sneed. It was edited by Jess Jiang, fact-checked by Sierra Juarez, and engineered by Valentina Rodriguez Sanchez. Alex Goldmark is Planet Money's executive producer.

Help support Planet Money and hear our bonus episodes by subscribing to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.

Learn more about sponsor message choices: podcastchoices.com/adchoices

NPR Privacy Policy

Toronto, ON — Inspired by the plight of Syrian refugees, and by the ongoing displacement of peoples in Toronto and abroad,  ART x BISSELL, in partnership with SKETCH and The Remix Project, is pleased to present Common Ground, the 2nd annual contemporary art exhibition at the University of Toronto’s Faculty of Information (iSchool). Curated by Master of Museum Studies students […]

The following is a link to the high school course description guide for 2024-25. It contains all of the classes and graduation requirements for high school students. Students should see their high school counselor with any questions regarding graduation requirements. Click here to access the Google document of the high school course description guide for […]

The post 2024-25 High School Course Description Guide appeared first on Forest Hills Public Schools.

TORONTO, ON-   The global paralysis on the Syrian crisis has led to the largest refugee crisis ever witnessed by the international community, with millions of Syrians being uprooted and displaced. The Canadian government has announced a plan to welcome 25,000 refugees by the end of February in 2016 but much work needs to be done […]

Ed Bastian, CEO of Delta Air Lines, leads a company that has been on the front lines of pandemic challenges.

Hybrid industrial cloud adoption will more than double over the next five years at 21.1% CAGR.

Many companies are looking ahead for ways to reskill their current workforce and retain their top talent.

Digital twins replicate real-world environments digitally, aiding manufacturers in optimizing processes and improving safety and performance.

The standardization of screw threads has been a historical endeavor involving several organizations. However, the ASME B1 Screw Thread Committee has emerged as the primary organization responsible for holding, updating, and curating these standards.

No robot can replace a person, but they can handle dull, dangerous, or repetitive tasks, freeing up employees for more fulfilling work. Businesses need to embrace robotics to efficiently adapt to production cycles and address supply chain backlogs and labor shortages.

Fatigue testing has made significant progress in recent years, especially in test and environmental conditions. Remote monitoring has advanced with the use of AI-enabled camera systems, making it easier to integrate legacy instruments.

Mahr Federal has introduced a new addition to their growing family of optical shaft measurement systems.

Today’s manufacturing environment demands greater product variety, shorter lead times, and higher customer expectations. To meet these challenges, manufacturers need agile and efficient intralogistics solutions, specifically scalable, modular systems that adapt to production changes and optimize resources while ensuring high quality.

Orders of manufacturing technology, measured by the U.S. Manufacturing Technology Orders (USMTO) report published by AMT – The Association For Manufacturing Technology, totaled $360.8 million in August 2024.

3D optical profiling, developed in the early 1990s, is crucial for high-resolution measurement of optics, semiconductors, medical devices, and precision machining. Recent developments have expanded its capabilities, allowing high-resolution surface texture measurements over many square millimeters in minutes.

TWO MEN IN CONVERSATION ATTEMPTING TO PUT THINGS LE CANVAS by James Christensen is a(n) Limited Edition. The Edition is Limited to Limited Edition of 475 pcs

Captivating Cattleya by Brian Davis is a(n) Limited Edition. The Edition is Limited to Limited Edition of 95 pcs

Source Energy Optimization, a Source Refrigeration & HVAC business unit, has launched a new website as part of a strategic expansion to meet the growing demand for energy optimization services among high-energy usage businesses.  

While implementing new technology may seem like a daunting task, seasoned technicians could find it’s not all that different than the work they are already doing.

A question I’m frequently asked is, where do you start when improving a poorly performing duct system? Do you tear it out and start over again, or is there an easier way? The good news is, there is a simple, logical pattern you can follow to optimize a duct system.

The use of UV-C in HVAC systems has proven to be an effective way to minimize the threat of volatile organic compounds (VOCs), small particles, and other airborne pathogens commonly found in health care environments.

Condensing boilers save space and time on installation, as installing a condensing boiler is a pretty seamless process for a few reasons.

As the industry continues to evolve, it’s essential for HVACR contractors to embrace comprehensive training programs that address both foundational knowledge and hands-on experience with CO₂ systems.

HVAC contractors have an underutilized tool available to help optimize their businesses: customer data.

EPA recently reported an increase in the total volume of HFCs reclaimed in 2023 compared to 2022.

Optimizing HVAC systems with new technology can result in a domino effect of benefits. One great example is the HVLS fan, which can boost HVAC system performance, efficiency, and sustainability.

Emerson spent more than three years researching and designing its 2018 Dealer Design Award gold-winning product in the Refrigeration and Ice Machines category.

Properly sealing and maintaining heating and cooling ducts is a low-cost measure that can improve energy efficiency.

AI promises to revolutionize IAQ, but first, it needs to overcome several challenges, like unreliable data, incomplete automation, and gimmicky solutions that fail to deliver real value.

Read this eBook to find out more on software solutions that help contractors reduce wasted time and cost.

While new technology can certainly help streamline certain aspects of HVAC business operations, like accounting and inventory management, it still needs to be viewed as a tool to augment the capabilities of employees, not replace them entirely.

By splitting the absorption process into two steps, lithium bromide solution concentrations are lower in the system, enabling lower hot water temperatures within the generator, lower hot water flow rates, and the elimination of crystallization risk within the chiller.

Troubleshooting refrigeration systems can be complex and frustrating, so put aside any assumptions and inspect the system thoroughly before making any diagnosis.

Efficient refrigeration and HVAC systems are essential to energy management and operational cost of residential, commercial, or industrial buildings.

Musk confirmed that his company could make use of their current heat pump technology to develop a smart HVAC system for home use.

A variable speed drive (VSD) controls the speed of the high-torque, direct-drive motor for optimal fan operation.

The growing electricity demands being placed on the country’s century-old grid are resulting in an increased number of unexpected power outages across the U.S.

AC drives are an essential part of the HVAC marketplace, and the growth of the market looks to be exceptional over the next few years. According to MarketsandMarkets, the market is expected to grow from an estimated $15.72 billion in 2016 to $22.07 billion by 2021.

Honeywell announced the launch of Honeywell Forge Energy Optimization, a cloud-based, closed-loop, machine learning solution.

The benefits of portables, including speedy implementation, reduced downtime, and cost-effectiveness, are continuing to gain recognition from end users. And, as end users experience these benefits and the resulting uptime, industry experts expect the portable market to continue to heat up.

When it comes to comfort, not much beats zoning. In fact, many industry experts tout that once homeowners have experienced the comfort zoning has to offer, they will never own another house without it.

Zoning technology has experienced success in both residential and commercial applications of hot water and hydronic systems.

Scandinavian green energy startup Aira plans to offer a 10-year service guarantee and a monthly fee that includes installation, maintenance.

Despite the arguments regarding the practicality of heat pumps in cold climates, residents of Maine have fully embraced them.

In this Episode, Alexander and Markus talk about scripting languages. Topics include the definition of what a scripting language is, typical usage scenarios, performance issues, programming styles and IDE support. In later Episodes we will talk about more specific topics, such as dynamic typing, reflection, functional programming as well as specific languages such as Ruby.

Felienne interviews Zachary Burt about freelancing as a career option. How does freelancing differ from employment? How to do personal marketing and sales? How to find a work-life balance when you are self-employed? We also cover practical tips like deciding on an hourly rate and managing demanding customers.

Kirk Pepperdine talks with Diomidis Spinellis about performance optimization. Topics include development practices, tools, as well as the role of software architecture, programming languages, algorithms, and hardware advances.