Ajay Devgn will also play a pivotal role in RRR.

Has RRR made Rs 1,000 crore at the box office? The makers certainly think so, and they held a grand event to celebrate the big feat.

'The moments of laughter you've gifted us will always remain.'

From Bollywood actors to designer Manish Malhotra, many took to social media to pay their respects to Rohit Bal, affectionately known as 'Gudda' by his admirers

A long-time fashion editor on the designer’s crowd-pulling persona that glossed over the empath he was 

Surely in the thousands of spectators across the country, there is someone with a sense of humour, someone who can raise a heckle without raising a hackle.

According to a copper plate of the Muthukumara Vijayaragunatha Sethupathi Kaathathevar, one will incur the sin of killing a Kaaram Pasu, if one misappropriates the proceeds from Pakkiri Puthukulam village donated to the Habil and Qabil Dargah, which is a few yards away from the house of late President A.P.J. Abdul Kalam

Sony  launched a new series of AI-driven smart 4K OLED televisions with studio calibrated mode in India.

A man who took in an orphaned squirrel and made it a social media star says New York state’s decision to seize and euthanize the animal won’t go without a response

The domain was previously owned by Dharmesh Shah, the co-founder and CTO of HubSpot who bought it last year for $15.5 million

Satellite Internet service Starlink’s parent SpaceX battled telcos’ anxieties on satellite internet encroaching on their market at a contentious discussion by the Telecom Regulatory Authority of India on Friday

Smart, flexible skins measure and adapt to ambient temperatures

Smart, flexible skins measure and adapt to ambient temperatures

Iron oxide particles and hydrogen peroxide bust biofilms on teeth in rat study

Fancy your chops are a designer? Skoda Auto India has a challenge for you. Rajesh Karkera/Rediff.com brings us the lowdown.

Deployment of autonomy will depend on legal understanding of liability, accountability

'The great singer Shardaji took Bhojpuri music and singing to the national and international level with her singing!'

The structure was produced by Turkish software company Etisan and is one of the club's main new hygiene measures to prevent the spread of the coronavirus at the training facilities.

Rabindranath Tagore, a popular Bengali-poet, artist, musician, Ayurveda researcher and polymath was born on 7 May 1861. He is often referred to as Gurudev, Kabiguru and Biswakabi by his admirers. During the late 19th century and early 20th century, he extensively

Each and every minute detail of Allu Arjun's Pushpa has left the fans super excited, ever since the inception. The movie is said to be an action thriller, wherein Allu Arjun will be seen doing some high-octane action sequences. Well, if

Before this, David and his wife Candice were seen grooving to recent Telugu hit track Butta Bomma from Allu Arjun starrer Ala Vaikuntapuramlo.

This has never happened to me before: I enjoyed the sequel more than the original! Be assured, though, My Side of the Mountain

is very good. Young Sam Gribley goes off to live in the wilderness quite comfortably in a huge hollow tree. He trains a young falcon he named Frightful:

"Every day I worked to train Frightful. It was a long process, I would put her on her stump with a long leash and step back a few feet with some meat in my hand. Then I would whistle. The whistle was supposed eventually to mean food to her. So I would whistle, show her the meat, and after many false flaps she would finally fly to my hand. I would pet her and feed her. She could fly fairly well, so now I made sure that she never ate unless he flew to my fist.

"One day at breakfast I whistled for Frightful. I had no food, she wasn't even hungry, but she came to me anyway. I was thrilled. She had learned a whistle meant 'come.'

"I looked into her steely eyes that morning and thought I saw a gentle recognition. She puffed up her feathers as she sat on my hand. I call this a 'feather word.' It means she is content."

I also enjoyed this, from near the end of the book: "I returned to my patch on the mountain, talking to myself all the way. I talk to myself a lot, but everyone does. The human being, even in the midst of people, spends nine-tenths of his time alone with the private voices of his own head. Living alone on a mountain is not much different, except that your speaking voice gets rusty, I talked inside my head all the way home, thinking up schemes, holding conversations with Bando and Dad and Matt Spell...
"I cooked supper, and then sat down by my little fire and called a forum. It is very sociable inside my head, and I have perfected the art of getting a lot of people arguing together in silence or in a forum, as I prefer to call it. I can get four people all talking at once, and a fifth can be present, but generally I can't get him to talk. Usually these forums discuss such things as a storm and whether or not it is coming, how to make a spring suit, and how to enlarge my house without destroying the life in the tree. Tonight, however, they discussed what to do about Matt Spell. Dad kept telling me to go right down to the city and make sure he published nothing, not even a made-up story. Bando said, no, it's all right, he still doesn't know where you live, and then Matt walked into the conversation and said that he wanted to spend his spring vacation with me, and that he promised not to do anything untoward. Matt kept using 'untoward' - I don't know where he got that expression, but he liked it and kept using it - that's how I knew Matt was speaking; everything was 'untoward.'"

What I liked there was that it seemed that author Jean Craighead George described how her stories got generated. Characters in her head interacted, and she transcribed what took place onto paper. I could be wrong, but maybe.

The sequel that I liked even more is called On the Far Side of the Mountain. There's a third book, Frightful's Mountain, but I have not read it yet. It's here at my desk, so it won't be long.

If pet owners often resemble their pets, then by proxy does that mean squee babies often resemble their pillows?

Although a robust inflammatory response is needed to combat infection, this response must ultimately be terminated to prevent chronic inflammation. One mechanism that terminates inflammatory signaling is the production of alternative mRNA splice forms in the Toll-like receptor (TLR) signaling pathway. Whereas most genes in the TLR pathway encode positive mediators of inflammatory signaling, several, including that encoding the MyD88 signaling adaptor, also produce alternative spliced mRNA isoforms that encode dominant-negative inhibitors of the response. Production of these negatively acting alternatively spliced isoforms is induced by stimulation with the TLR4 agonist lipopolysaccharide (LPS); thus, this alternative pre-mRNA splicing represents a negative feedback loop that terminates TLR signaling and prevents chronic inflammation. In the current study, we investigated the mechanisms regulating the LPS-induced alternative pre-mRNA splicing of the MyD88 transcript in murine macrophages. We found that 1) the induction of the alternatively spliced MyD88 form is due to alternative pre-mRNA splicing and not caused by another RNA regulatory mechanism, 2) MyD88 splicing is regulated by both the MyD88- and TRIF-dependent arms of the TLR signaling pathway, 3) MyD88 splicing is regulated by the NF-κB transcription factor, and 4) NF-κB likely regulates MyD88 alternative pre-mRNA splicing per se rather than regulating splicing indirectly by altering MyD88 transcription. We conclude that alternative splicing of MyD88 may provide a sensitive mechanism that ensures robust termination of inflammation for tissue repair and restoration of normal tissue homeostasis once an infection is controlled.

Musician Bono turns 60 and race car driver Helio Castroneves turns 45, among the famous birthdays for May 10.

Testimony of Marc R. Rosenblum, Deputy Director, U.S. Immigration Program, before the House Committee on Homeland Security Subcommittee on Oversight and Management Efficiency.

Norwegian Bible school students on mission trip to South Africa, shares the Gospel at the garbage dump outside Pretoria

IT should really be remembered as one of Danny McGrain’s finest hours, not Scottish football’s darkest days.

Scores of nature lovers from dozens of states crowded trails, blocked-off areas.

David Warner, dressed in his SRH kit with a bat in hand, delivered the dialogue with much gusto and asked his fans to guess the movie.

Yamaha, Suzuki and TVS are away from this segment while Bajaj's portfolio has shrunk to only bike in the 125cc space.

A horrific video of a Royal Enfield falling from a trailer has surfaced on the web. Watch what exactly happened!

In a statement, GSTN said this new functionality on the GST portal is aimed at providing a major relief to taxpayers, especially at the time of the COVID-19 crisis when there is limited access to cash resources.

Hong Kong and Federal Republic of Germany have signed a Memorandum of Understanding (MOU) concerned with the automated clearance service usage on a shared basis. The MOU is considered as a new milestone in the collaboration between the countries in immigration…